2003 Volume 14 Issue 6

First Enantioselective Synthesis of Daphneticin
Xin Feng REN , Kun PENG , Xiao Chuan CHEN , Xin Gang XIE , Ya Mu XIA , Xin Fu PAN
2003, 14(6): 551-554
[Abstract](169) [FullText HTML] [PDF 1385KB](1)
An enantioselective total synthesis ofchiral daphneticin is reported firstly.
Regioselective Oxidation of Phenols to o-Quinones with Dess-Martin Periodinane(DMP)
Hui Bing LUO , Yu Yuan XIE
2003, 14(6): 555-556
[Abstract](199) [FullText HTML] [PDF 589KB](9)
Regioselective oxidation of phenols to o-quinones with Dess-Martin periodinane isreported.
The Reaction of Tanshinones with Amines
Lin Kun AN , Xian Zhang BU , Hai Qiang WU , Xin Dong GUO , Lin MA , Lian Quan GU
2003, 14(6): 557-560
[Abstract](243) [FullText HTML] [PDF 1867KB](1)
The reaction of cryptotanshinone and tanshinone ⅡA with several biogenic aminemetabolites involved in the pathogenic pathways of HE were investigated and eight 1,2,3,4-tetrahydrophenanthrene derivatives, 2-6 and 8-10, were obtained. The probable mechanism onreaction was discussed.
Study on the Reaction of Benzimidazolium Salt with Amine Compounds
Yun Xia WANG , Lin JIA , Zhen SHI
2003, 14(6): 561-564
[Abstract](159) [FullText HTML] [PDF 1279KB](0)
The addition-hydrolysis reaction of benzimidazolium salt with some mono- andbifunctional amine nucleophiles is reported, and a novel method of biomimetic synthesis forformamides and heterocycle compounds is provided.
Synthesis of 5-Aryl-1, 2-dihydro-1-pyrrolizinones
Hong YU , Fei WANG , Shou Fang ZHANG
2003, 14(6): 565-568
[Abstract](771) [FullText HTML] [PDF 1514KB](3)
In order to search for new potent anti-inflammatory and analgesic agents inpyrrolizinones, the title compounds were designed and synthesized. A series of the compoundswere prepared with two different synthetic schemes. Some of the compounds showed remarkableanti-inflammatory and/or analgesic activities on mice.
Synthesis of 3-Biaryl-1-ferrocenyl-2-propene-1-ones
Qing Bao SONG , Shang Dong YANG , Tian Hua SHEN , Yong Qiang WANG , Yong Xiang MA , Xiao Li WU
2003, 14(6): 569-571
[Abstract](741) [FullText HTML] [PDF 994KB](0)
The novel structures of organometallic compounds 3-biaryl-1-ferrocenyl-2-propene-1-ones 5 were synthesized for nonlinear optical chromophores by Suzuki cross-coupling reaction.Their structures were determined with elemental analyses, 1H NMR spectra and 13C NMR spectra.
Synthesis of 2, 6-(substituded) pyridine Derivatives Using Amide and Imine Groups
Mei Ying LI , Pei Zhi HU , Wan Ren ZHU , Kuo Xi XU
2003, 14(6): 572-574
[Abstract](165) [FullText HTML] [PDF 1244KB](0)
A new 'two-armed' acyclic diamide a 2, 6-bis(1-ethanecarbozamido-2-amino)pyridine,and a new series of aromatic aldehyde schiff bases containing pyridine ring and amide bridge, a-f,were prepared. The compounds were characterized by elemental analysis, IR, 1HNMR and MS.The bioactivity half inhibitory concentration C1/2is given.
Photopromoted Carbonylation of Alkyl Halides Under Ambient Conditions
Yan SUN , Jing Mei YIN , Da Bin GAO , Guang Yun ZHOU , Ying Ping JIA
2003, 14(6): 575-578
[Abstract](281) [FullText HTML] [PDF 1488KB](1)
Photopromoted carbonylation of alkyl halides with carbon monoxide can be carried outunder ambient conditions with non-precious transition metal complexes (such as cobalt complexes) catalysts. Our preliminary work showed that alkyl halides can be transformed into alkene andalkane directly under irradiation, but the esters can not be transformed. It is assumed that thecarbonylation of alkyl halides may be proceeded in two ways.
Synthesis of a New Ligand Containing 1, 7-Diaza-12-crown-4 and the Application in Asymmetric Cyclopropanation Reaction
Cheng Yun WANG , Zhi Cai SHANG , Jiang Hua MEI , Qing Sen YU
2003, 14(6): 579-580
[Abstract](176) [FullText HTML] [PDF 757KB](0)
A new chiral multidenate ligand (S, S)-1,7-bis(4-benzyloxazolin-2-yl-methyl)-1,7-diaza- 12-crown-41 has been synthesized and used as ligand in the copper catalyzed asymmetriccyclopropanation of 1, 1-diphenylethylene.
Design and Synthesis of New Arylsulfonamide and Arylamide Derivatives for the Platelet Aggression Inhibitor
Song Qing WANG , Xiu Jie LIU , Zhi Ming YI , Kang ZHAO
2003, 14(6): 581-584
[Abstract](162) [FullText HTML] [PDF 1274KB](0)
A series of arylsulfonamide and arylamide derivatives have been prepared from anisolein good yields. The structures of those compounds were confirmed by 1H-NMR and MS analysis.Their activities against platelet aggregation were tested in vitro by using the Born test on rabbits.
A New Disulfated Triterpene Glycoside from the Sea Cucumber Mensamaria intercedens Lampert
Zheng Rong ZOU , Yang Hua YI , Qiang Zhi XU , Hou Ming WU , Hou Wen LIN
2003, 14(6): 585-587
[Abstract](227) [FullText HTML] [PDF 925KB](0)
A new disulfated triterpene glycoside named intercedenside B was isolated from the seacucumber Mensamaria intercedens Lampert. The structure was deduced from the spectral data.
A New Cytotoxic Acetogenin from the Seeds of Annona squamosa
Hai Hui XIE , Xiao Yi WEI , Ji Dong WANG , Mei Fang LIU , Ren Zhou YANG
2003, 14(6): 588-590
[Abstract](175) [FullText HTML] [PDF 1060KB](0)
new Annonaceous acetogenin, squamostolide (1), was isolated from the seeds of Annona squamosa. Its structure was elucidated based on spectroscopic methods and comparisonwith known compounds. It is the first example of Annonaceous acetogenin with each of the twoends of the aliphatic chain bearing a γ-lactone. The new compound exhibited cytotoxic activity invitro against bel-7402 and CNE2 human tumor cell lines.
Two New Abietane Quinones from Isodon lophanthoides var. Micranthus
Ai Hua ZHAO , Sheng Hong LI , Yong Wei LI , Quan Bin HUAN , Qin Shi ZHAO , Zhong Wen LIN , Han Dong SUN
2003, 14(6): 591-593
[Abstract](161) [FullText HTML] [PDF 1028KB](0)
The structures of two new abietane quinones, named micranthins A and B, weredetermined to be 7α-methoxy-14, 16-epoxy-8, 13-abietadiene-11, 12-dione (1) and 16-acetoxy-6,7-dehydroroyleanone (2) respectively, which were isolated from Isodon lophanthoides var.micranthus.
A New Cycloartane from Sphaerophysa salsula
Zhong Jun MA , Xian LI , Yang LU , Cheng WANG , Qi Tai ZHENG
2003, 14(6): 594-596
[Abstract](172) [FullText HTML] [PDF 1021KB](0)
A novel cycloartane, named sphaerophysone A, 9, 19-cycloart-7β, 24β, 25-triol-1-en-3-one, was isolated from the ethanol extract of Sphaerophysa salsula DC. The structure waselucidated on the basis of spectral evidences and confirmed by X-ray analysis, the stereochemistryof the compound was also defined by X-ray analysis.
A Morphinane Alkaloid from Meconopsis quintuplinervia
Xiao Ya SHANG , Hai Sheng JIAO , Yong Chun YANG , Jian Gong SHI
2003, 14(6): 597-598
[Abstract](184) [FullText HTML] [PDF 788KB](0)
A new morphinane alkaloid named as mecoquitupline was isolated from Meconopsis quintuplinervia Regel. Its structure was elucidated to be 6-methoxy-17-methyl-2,3-[methylenebis(oxy)]-morphinan-5-en-7-one by spectroscopic techniques.
An On-line Galvanic Cell Generated Electrochemiluminescence and Flow Injection Determination of Calcium in Milk and Vegetable
Li Rong LUO , Jia Gen LÜ , Zhu Jun ZHANG
2003, 14(6): 599-602
[Abstract](309) [FullText HTML] [PDF 1262KB](0)
An on-line Ag/Al galvanic cell is investigated and employed to generateelectrochemiluminescence (ECL). The potential of the galvanic cell could be adjusted by varyingthe components of flow reagent. The cell performed perfect capability of supplying a stablepotential for ECL generation. Based on the weak ECL ofcalcein blue could be greatly sensitizedby the presence of calcium in alkaline solution, calcium contents in milk samples and in cabbagewere assayed and the results were compared with those from ICP-AES method.
Separation of Ephedrines Using 1-Butyl-3-methylimidazolium-tetrafluoroborate Ionic Liquids as Eluent in High-performance Liquid Chromatography (HPLC)
Li Jun HE , Wen Zhu ZHANG , Bo WEN , Xia LIU , Sheng Xiang JIANG
2003, 14(6): 603-604
[Abstract](175) [FullText HTML] [PDF 674KB](1)
A simple, effective HPLC method for separation of ephedrines was achieved by using1-butyl-3-methylimidazolium-tetrafluoroborate ionic liquid solution (0.1% v/v) as eluent at pH 3.0.The involved mechanism may be due to that the imidazolium cations can effectively shield thesilanol groups of alkylsilica surface, thereby decreasing band tailing and increasing the separationefficiency.
Coordination Structure of Aluminum in Magnesium Aluminum Hydroxide Studied by 27Al NMR
Shu Hua HAN , Wan Guo HOU , Wen Xiu DANG , Jun XU
2003, 14(6): 605-608
[Abstract](178) [FullText HTML] [PDF 1287KB](2)
The coordination structure of aluminum in magnesium aluminum hydroxide was studiedby 27Al NMR. The result showed that tetrahedral aluminum (Al) existed in magnesiumaluminum hydroxide, and the contents of Al increased with the increase of the ratio of Al/Mg andwith the peptizing temperature. Al originated from the so-called Al13 polymer with the structureof one Al tetrahedron surrounded by twelve Al octahedrons.
The Application of Polytetrafluoroethylene (PTFE) Fiber Grafted Acrylic Acid as a Cation Exchanger for Removing Cu2+
Zheng Pu ZHANG , Zhi Peng WANG , Bao Gui ZHANG , Yan Geng ZHANG
2003, 14(6): 609-610
[Abstract](174) [FullText HTML] [PDF 650KB](0)
The polytetrafluoroethylene fiber grafted acrylic acid was used as a cation exchanger.The exchange capacity of the cation fiber is 3.06 mmol/g. The maximum Cu2+ adsorptioncapacity is 107.48 mg/g. It could be desorbed completely by 1 mol/L HCl.
Separation of Peptides by Pressurized Capillary Electrochromatography
Kai ZHANG , Chao YAN , Zhi Chao ZHANG , Qin Sun WANG , Ru Yu GAO
2003, 14(6): 611-614
[Abstract](209) [FullText HTML] [PDF 1352KB](0)
A novel gradient pressurized capillary electrochromatography (pCEC) instrument wasdeveloped to separate peptides. Two gradient elution modes, hydrophobic and hydrophilicinteraction mode in pCEC, were performed on this instrument. Baseline separation of sixpeptides was obtained on two gradient modes with C18 column and strong cationic exchangecolumn respectively. The effects of mixer volume and total flow rate of pumps on resolutionwere also discussed.
Highly Efficient, Green Oxidation of Alcohols Using Novel Heterogeneous Ruthenium Catalyst
Hong Bing JI , Yu QIAN
2003, 14(6): 615-618
[Abstract](257) [FullText HTML] [PDF 1532KB](0)
MnFe1.4Ru0.45Cu0.15O4 was an effective heterogeneous catalyst for the oxidation ofvarious types of alcohols to the corresponding carbonyl compounds using atmospheric pressure ofoxygen under mild conditions. Furthermore, this catalyst was also effective towards alcoholoxidation using water as solvent instead of toluene.
Microcalorimetric Study on Tyrosine Oxidation Catalyzed by Tyrosinase
Jun YAO , Yi LIU , Tian Zhi WANG , Jian Ben LIU , Peng LIU , Zi Niu YU
2003, 14(6): 619-622
[Abstract](180) [FullText HTML] [PDF 1341KB](0)
Through the method of initial heat release rate, the kinetic property of tyrosine oxidationcatalyzed by tyrosinase from Pseudomonas maltophilia was investigated using a LKB-2107 batchmicrocalorimeter. Tyrosine was catalyzed and oxidized into L-dopa, then into melanin catalyzed bytyrosinase. We found that the tyrosinase reaction obeyed the Michaelis-Menten kinetics, and at298.15K and pH 7.0, the initial exothermic rate (Ω0) are in the range of0.1567~0.5704 mJ·s-1, the maximum exothermic rate (Ωmax) are in 0.4152~0.8143mol·L-1, and mean value of the Michaelisconstant (Km) is 2.199±0.105×104 mol·L-1.
The Performance of Rhodium Complex-diphosphine Systems in the Hydroformylation of 1-Dodecene
Xue Yuan HUANG , Rui Xiang LI , Hua CHEN , Xian Jun LI
2003, 14(6): 623-626
[Abstract](170) [FullText HTML] [PDF 1297KB](0)
The catalytic performances of four HRh(CO)(PPh3)3-diphosphine (BISBI, BDPX,BDNA and BINAP) systems in 1-dodecene hydroformylation were investigated and comparedwith HRh(CO)(PPh3)3-PPh3system. The catalyst system HRh(CO)(PPh3)3- BISBI exhibited veryhigh regioselectivity for the formation of linear aldehyde.
Dioxygen Affinities and Catalytic Oxidation Performance of Cobalt (Ⅱ) Complexes with N-Aryl Hydroxamic Acid
Chun Chun ZHANG , Wei ZENG , Jian Zhang LI , Sheng Ying QIN
2003, 14(6): 627-630
[Abstract](175) [FullText HTML] [PDF 1524KB](0)
The oxygenation of cobalt (Ⅱ) hydroxamates (CoL2) and its catalytic performance inoxidation of p-xylene to p-toluic acid (PTA) were examined. The effects of X and Y bonded tohydroxamate group on dioxygen affinities and catalytic oxidation performance were alsoinvestigated.
Hydrogen Production from Methanol Using Corona Discharges
Xi Zhen LIU , Chang Jun LIU , Baldur ELIASSON
2003, 14(6): 631-633
[Abstract](169) [FullText HTML] [PDF 1127KB](1)
Hydrogen production at room temperature from liquid methanol has been conductedusing corona discharge. The content of water in methanol solution has a significant effect on thisproduction. When water concentration increases from 1.0% to 16.7%, the methanol conversionrate changes from 0.196 to 0.284 mol/h. An important finding in this investigation is theformation of ethylene glycol as a major by-product. The yield of ethylene glycol is ranged from0.0045 to 0.0075 mol/h based on the water content.
First Binary Mixture Ionic Liquids Containing EMIMBr and IM
Li Yi DAI , Chun Yan HUA , Sheng Rong YE , Yong Kui SHAN , Ming Yuan HE
2003, 14(6): 634-636
[Abstract](175) [FullText HTML] [PDF 984KB](5)
A new series of binary mixture ionic liquids comprising 1-ethyl-3-methylimidozaliumbromide (EMIMBr) and imidazole (IM) have been synthesized. The melting points of the ionicliquids vary with the different content of IM while they still keep satisfactory conductivity andviscosity. According to the analysis of its phase diagram, the eutectic point is about 16.5℃ withthe mass percentage of IM 29%.
Cubic Mesoporous Aluminosilicate with Primary Structure Units of Zeolite Beta in the Pore Wall
Gong LI , Qiu Bin KAN , Tong Hao WU , Jia Hui HUANG
2003, 14(6): 637-640
[Abstract](169) [FullText HTML] [PDF 1548KB](0)
Mesoporous aluminosilicate with cubic ordered structure was synthesized by two-stepcrystallization, which showed stronger acid sites and more effective activity for catalytic alkylationof 2, 4-ditert-butylphenol with tert-butanol than conventional H-AlMCM-48 materials.
Enhancement of Photocurrent Generation of a Novel Stilbazolium Dye Dimer in LB Monolayer Films
Fu You LI , Xiao Rong ZOU , Chun Hui HUANG
2003, 14(6): 641-644
[Abstract](164) [FullText HTML] [PDF 1415KB](0)
A novel dye dimer, bis-{[1-(N-hexadecyl-4-pyridinium)-2-(4-N, N-dimethylamino-phenyl)] ethenyl}methane diiodide (C16BP) was synthesized, and the photoelectrochemistry of thedye Langmuir-Blodgett monolayer modified ITO electrode was investigated. For comparison, thephotoelectrochemistry of the monomer (E)-N-hexadecyl-4-[2-(4-N, N-dimethylaminophenyl)ethenyl] pyridinium iodide (C16P) was also measured. The results show that the photocurrentgeneration property of the dimer is enhanced. The photocurrent generation quantum yield is0.38% for C16BP, while that for C16P is 0.23%.
Synthesis of Various Types of Silver Nanoparticles Used as Physical Developing Nuclei in Photographic Science
Jun Ping ZHANG , Li Qi SHENG , Ping CHEN
2003, 14(6): 645-648
[Abstract](179) [FullText HTML] [PDF 1314KB](0)
Ag nanoparticles used as physical developing nuclei in photographic science wereprepared by reduction method. The as-formed Ag nanoparticle colloid was characterized byUV-Vis absorption spectrum, Atomic Force Microscopy(AFM) and Charge Coupled Device (CCD)technique. It is found that the source of Ag ions, the addition of surfactant and polymer, all havegreat influence on the size, topography and catalytic activity of Ag nanoparticles.
The Photocatalyzed Reduction of Aqueous Sodium Carbonate Using Nano SrFeO3
Qiu Hua YANG , Xi Xian FU
2003, 14(6): 649-652
[Abstract](171) [FullText HTML] [PDF 1281KB](0)
Heterogenous photocatalyzed reduction of aqueous Na2CO3 has been carried out byusing nano SrFeO3 semiconductor powders. Formic acid, formaldehyde and methyl alcoholwere identified as photoproducts, and were measured spectrophotometrically. The effect of thevariation of different parameters such as sodium carbonate concentration, amount of photocatalystand different light sources on the yield of photoproducts was also investigated. It shows thatnano SrFeO3 has photocatalytic activity. Irradiation leads to the production of electrons in theconduction band of the SrFeO3 semiconductor. It is likely that the photoproduced electronsreduce CO32- initially to HCOO-, and then to HCHO and CH3OH.
Synthesis and Surface Activity of Novel Triazole-based Cationic Gemini Surfactants
Ling Guang QIU , An Jian XIE , Yu Hua SHEN
2003, 14(6): 653-656
[Abstract](157) [FullText HTML] [PDF 1306KB](0)
The synthesis and surfactant activities of two new cationic gemini surfactants containingtriazole compound as spacer were described. Their critical micelle concentrations (CMC), whichare 1.8×l0-4 mol/L and 3.9×10-4 mol/L respectively, are much lower than that of conventionalsurfactant cetyltrimethyl ammonium chloride (CTAC). In addition, compared with some geminisurfactants containing phenylene, xylylene and stilbenyl as spacer, this new kind of surfactants hasgood solubility in water at room temperature because of containing more hydrophilic groups oratoms in molecules.
Two-photon Excited Fluorescence of Bithiophene Derivatives
Guang Ming XIA , Qi FANG , Xin Guang XU , Gui Bao XU , Wei WANG , Zhi Qiang LIU , Gui Lan SONG , Yong Jie WU
2003, 14(6): 657-660
[Abstract](166) [FullText HTML] [PDF 1440KB](0)
Two new bithiophene derivatives named as 5, 5'-bis(p-N,N-dimethylaminostyryl)-2, 2'-bithiophene (BMSBT), and 5, 5'-bis(p-N,N-diethylaminostyryl)-2, 2'-bithiophene (BESBT) havebeen synthesized. Both compounds can emit strong single-photon excited fluorescence (SPEF)and two-photon excited fluorescence (TPEF) with the emission peaks around ~560 nm and withthe lifetime of~lns.
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