Citation: Li Jun HE, Wen Zhu ZHANG, Bo WEN, Xia LIU, Sheng Xiang JIANG. Separation of Ephedrines Using 1-Butyl-3-methylimidazolium-tetrafluoroborate Ionic Liquids as Eluent in High-performance Liquid Chromatography (HPLC)[J]. Chinese Chemical Letters, ;2003, 14(6): 603-604. shu

Separation of Ephedrines Using 1-Butyl-3-methylimidazolium-tetrafluoroborate Ionic Liquids as Eluent in High-performance Liquid Chromatography (HPLC)

Lanzhou Institute of Chemical Physics, Chinese Academy of Science, Lanzhou 730000

Received Date: 22 July 2002

A simple, effective HPLC method for separation of ephedrines was achieved by using1-butyl-3-methylimidazolium-tetrafluoroborate ionic liquid solution (0.1% v/v) as eluent at pH 3.0.The involved mechanism may be due to that the imidazolium cations can effectively shield thesilanol groups of alkylsilica surface, thereby decreasing band tailing and increasing the separationefficiency.
- Ionic liquid,
- ephedrine,
- HPLC
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