Citation: Qin Ting, Mo Li, Chen Pingping, An Xuejie, Chen Zhiming. Syntheses of 1, 4-Dihydropyridine Derivatives Catalyzed by BINOL Multi-Hydrogen Bonded Thiourea[J]. Chemistry, ;2020, 83(7): 665-671. shu

Syntheses of 1, 4-Dihydropyridine Derivatives Catalyzed by BINOL Multi-Hydrogen Bonded Thiourea

Key Laboratory of Functional Materials Chemistry of Guizhou Province, School of Chemistry and Materials Science, Guizhou Normal University, Guiyang, 550001

Corresponding author: Chen Zhiming, czm000219@163.com
Received Date: 12 January 2020
Accepted Date: 25 February 2020

Figures(1)

Three kinds of structure-symmetric thiourea catalysts containing multi-hydrogen bond with binol axial chiral were synthesized and successfully applied to the syntheses of 1, 4-dihydropyridine derivatives. The results showed that the synthesized polyhydrogen-bonded thioureas have better catalytic activity, which can effectively improve the yield and enantioselectivity of the 1, 4-dihydropyridine derivatives. All new compounds were characterized by ¹H NMR、¹³C NMR、IR、melting point and so on.
- Catalyst,
- 1, 4-Dihydropyridine,
- Thiourea,
- Synthesis
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