Citation: Shipeng WANG, Shangyu XIE, Luxian LIANG, Xuehong WANG, Jie WEI, Deqiang WANG. Piezoelectric effect of Mn, Bi co-doped sodium niobate for promoting cell proliferation and bacteriostasis[J]. Chinese Journal of Inorganic Chemistry, ;2024, 40(10): 1919-1931. doi: 10.11862/CJIC.20240094 shu

Piezoelectric effect of Mn, Bi co-doped sodium niobate for promoting cell proliferation and bacteriostasis

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  • A bone repair material of Mn, Bi co-doped sodium niobate with piezoelectricity was prepared using the hydrothermal method. The microscopic morphology, composition, piezoelectricity, sonodynamic and enzyme-like activity of the material was characterized by scanning electron microscope, X-ray diffractometer, X-ray photoelectron spectrometer, piezoelectric force microscope, electrochemical workstation, ultraviolet-visible-near-infrared spectrometer, and electron paramagnetic resonance spectrometer. The results demonstrate that the material possesses both piezoelectric properties and enzyme-like activity; the ultrasound-triggered piezoelectric effect not only promotes cell proliferation but also enhances sonodynamic and enzyme-like activity, which generates reactive oxygen species for synergistic killing of bacteria/removal of biofilm.
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