Citation: Xin Zhang, Shuo Li, Chenghao Zhu, Xu-Lang Chen, Lijun Mao, Da Ma. Synergistic regulation of rate of the dissipative molecular switches via host-guest design and fuel engineering[J]. Chinese Chemical Letters, ;2026, 37(12): 112483. doi: 10.1016/j.cclet.2026.112483 shu

Synergistic regulation of rate of the dissipative molecular switches via host-guest design and fuel engineering

Xin Zhang ^{a, *,} ,
Shuo Li ^a ,
Chenghao Zhu ^a ,
Xu-Lang Chen ^b ,
Lijun Mao ^{a, *,} ,
Da Ma ^{a, *,}

a.
Zhejiang Key Laboratory of New Drug Development for Central Nervous System Diseases & Institute for Advanced Studies, Taizhou University, Taizhou 318000, China
b.
Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, College of Chemistry and Chemical Engineering, Hubei Normal University, Huangshi 435002, China

zx91318@163.com

lucienmlj@163.com

dama@tzc.edu.cn

Received Date: 22 October 2025
Revised Date: 22 January 2026
Accepted Date: 30 January 2026
Available Online: 31 January 2026

Figures(4)

Guest substituent electronic effects and chemical fuel selection govern the kinetics of anion-responsive dissipative molecular switches. Using Texas-sized macrocycles (Na-TxSB/An-TxSB) and 17 para-phthalic acid dianion guests, time-resolved UV–vis spectroscopy reveals substituent-dependent the half reaction time (t_1/2) and fuel-driven rate modulation ((2-cyano-2-(p-tolyl)propanoic acid (ACA2) accelerated switching up to 6-fold vs. trichloroacetic acid (ACA1)). DFT calculations established a proportional relationship between guest Mulliken charge and t_1/2, rationalizing kinetic trends confirmed with both hosts. This provides design principles for tailoring dissipative switches via host-guest and fuel engineering.
- Macrocycle,
- Dynamics study,
- Tetra-imidazolium salt,
- Dissipative molecular switches,
- Host-guest interaction
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沈阳化工大学材料科学与工程学院沈阳 110142