Citation: Ting Zhang, Yi-Ting Shao, Bin Wang, Zhang-Bin Pan, Yu-Ping Li, Hong-Bin Cao, Li-An Hou. Innovative research progress of antibiotic wastewater treatment technologies based on the whole-chain approach[J]. Chinese Chemical Letters, ;2026, 37(7): 112160. doi: 10.1016/j.cclet.2025.112160 shu

Innovative research progress of antibiotic wastewater treatment technologies based on the whole-chain approach

Ting Zhang ^a ,
Yi-Ting Shao ^b ,
Bin Wang ^c ,
Zhang-Bin Pan ^d ,
Yu-Ping Li ^a ,
Hong-Bin Cao ^{a, *,} ,
Li-An Hou ^{e, *,}

a.
Key Laboratory of Green Process and Engineering, Beijing Engineering Research Center of Process Pollution Control, Chemistry & Chemical Engineering Data Center, CAS, National Engineering Research Center of green recycling for strategic metal resources, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
b.
School of Life and Environmental Sciences, Minzu University of China, Beijing 100081 China
c.
College of Civil Engineering, Guizhou University, Guiyang 550025, China
d.
Shandong Province Water Supply and Drainage Monitoring Center, Ji’nan 250101, China
e.
School of Environment, Beijing Normal University, Beijing 100875, China

hbcao@ipe.ac.cn

h20091957@126.com

Received Date: 10 April 2025
Revised Date: 13 September 2025
Accepted Date: 21 November 2025
Available Online: 22 November 2025

Figures(6)

The wastewater produced in the antibiotic manufacturing process is a significant source of antibiotic pollution in the aquatic environment, posing a severe threat to ecological health and human well-being. Researchers have explored various methods, including source reduction technologies such as enzymatic engineering and green process control, to enhance antibiotic extraction efficiency. In addition, high-efficiency end-of-line processing technology has also been widely developed. This review first provides a detailed introduction to the characteristics of various antibiotics and their distribution levels in the environment. Then we systematically summarize and analyze the full-chain antibiotic end-of-pipe treatment processes, including conventional treatment processes and typical advanced treatment processes. Especially compares and analyzes the removal efficiency and carbon emissions of different conventional treatment processes, aiming to select efficient and low-carbon treatment processes. We intend to provide effective solutions to tackle the issue of antibiotic pollution while ensuring public health and ecological security.
- Antibiotic,
- Wastewater,
- Source reduction,
- End-of-pipe treatment,
- Carbon emission
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沈阳化工大学材料科学与工程学院沈阳 110142