Citation: Chaofan Zhang, Hongyu Dong, Xueyang Zhao, Cheng Fang, Yanbin Tong, Junfeng Niu. Research progress on the evolution of antidepressant-type pollutants during biological treatment of municipal wastewater[J]. Chinese Chemical Letters, ;2026, 37(6): 112038. doi: 10.1016/j.cclet.2025.112038 shu

Research progress on the evolution of antidepressant-type pollutants during biological treatment of municipal wastewater

Chaofan Zhang ^a ,
Hongyu Dong ^a ,
Xueyang Zhao ^b ,
Cheng Fang ^c ,
Yanbin Tong ^{a, *,} ,
Junfeng Niu ^{a, d, *,}

a.
School of Chemistry and Chemical Engineering/Key Laboratory of Environmental Monitoring and Pollutant Control, Shihezi University, Shihezi 832003, China
b.
School of Environmental Science and Engineering, Southwest Jiaotong University, Chengdu 611756, China
c.
Global Centre for Environmental Remediation (GCER), University of Newcastle, Callaghan, NSW 2308, Australia
d.
College of Environmental Science and Engineering, North China Electric Power University, Beijing 102206, China

tongyanbin@sina.com

niujf@ncepu.edu.cn

Received Date: 12 March 2025
Revised Date: 28 October 2025
Accepted Date: 29 October 2025
Available Online: 30 October 2025

Figures(8)

Antidepressants (ATDs) have negative impacts on the ecosystem and have been detected globally in concentrations ranging from approximately 0.17 ng/L to 4237 ng/L in municipal wastewater treatment plant influent. However, the removal of ATDs by biological methods is still unsatisfactory at present, due to the extremely complex removal pathway and various removal processes for different ATDs. Therefore, there is an urgent need for a systematic compendium to help people understand the biodegradation process of ATDs. This work provides an overview of the classification, physicochemical properties, and environmental sources of ATDs; systematically reviews the adsorption behaviors and transformation processes of various ATDs during biological treatment; examines the removal efficiency, degradation mechanisms, and critical operating conditions of bioreactors; and discusses the mechanism of ATD adsorption and removal by extracellular polymers secreted by microbial cells during the biological treatment of municipal wastewater. This work clarifies the evolution of different types of ATDs during municipal wastewater biological treatment and proposes future research avenues for the more efficient removal of ATDs.
- Antidepressants,
- Biological treatment,
- Biotransformation pathway,
- Ecotoxicity,
- Environmental concentrations
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沈阳化工大学材料科学与工程学院沈阳 110142