Citation: Li-Hong Xiong, Liang Chen, Zhi-Tao He. Stereoselective in situ assembled hydrofunctionalization and cascade[J]. Chinese Chemical Letters, ;2026, 37(3): 111921. doi: 10.1016/j.cclet.2025.111921 shu

Stereoselective in situ assembled hydrofunctionalization and cascade

Li-Hong Xiong ^{a, b, 1} ,
Liang Chen ^{b, c, 1} ,
Zhi-Tao He ^{a, b, c, d, *,}

a.
College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China
b.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai 200032, China
c.
School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China
d.
Ningbo Zhongke Creation Center of New Materials, Ningbo 315899, China

hezt@sioc.ac.cn

Received Date: 27 May 2025
Revised Date: 17 September 2025
Accepted Date: 29 September 2025
Available Online: 29 September 2025

Figures(5)

Hydrofunctionalization of unsaturated hydrocarbons via transition metal catalysis is a powerful route to prepare allyl skeletons, but is limited to mono- and two-component transformation models. Here we describe a novel protocol for the unprecedented three-component hydrofunctionalization via in situ formed diene species. Both amines and stabilized carbon nucleophiles undergo the assembled hydrofunctionalization with various olefins and alkenyl bromides through Pd-catalyzed tandem Heck coupling and outer-sphere allylation, generating allylic C–N and C–C bonds in reasonable yields and with excellent regioselectivities. In particular, the combination of assembled hydrofunctionalization and following derivatizations enables new access to a series of valuable substituted cyclic skeletons. Preliminary mechanistic studies support the in situ formation of critical conjugated diene intermediate for sequential hydrofunctionalization
- Hydrofunctionalization,
- Three-component,
- Stereoselective,
- Cascade,
- Diene species
1. [1]
  P. Koschker, B. Brei, Acc. Chem. Res. 49 (2016) 1524–1536. doi: 10.1021/acs.accounts.6b00252
2. [2]
  Y. Zheng, W. Zi, Tetrahedron Lett. 59 (2018) 2205–2213. doi: 10.1016/j.tetlet.2018.04.057
3. [3]
  G. Li, X. Huo, X. Jiang, et al., Chem. Soc. Rev. 49 (2020) 2060–2118. doi: 10.1039/c9cs00400a
4. [4]
  N.J. Adamson, S.J. Malcolmson, ACS Catal. 10 (2020) 1060–1076. doi: 10.1021/acscatal.9b04712
5. [5]
  R. Blieck, M. Taillefer, F. Monnier, Chem. Rev. 120 (2020) 13545–13598. doi: 10.1021/acs.chemrev.0c00803
6. [6]
  A. Flaget, C. Zhang, C. Mazet, ACS Catal. 12 (2022) 15638–15647. doi: 10.1021/acscatal.2c05251
7. [7]
  G. Cera, G. Maestri, ChemCatChem 14 (2022) e202200295. doi: 10.1002/cctc.202200295
8. [8]
  C. Ma, Y.W. Chen, Z.T. He, Sci. Sin. Chim. 53 (2023) 474–484. doi: 10.1360/ssc-2022-0196
9. [9]
  Y.C. Wang, J.B. Liu, Z.T. He, Chin. J. Org. Chem. 43 (2023) 2614–2627. doi: 10.6023/cjoc202302010
10. [10]
  F. Panahi, F. Bauer, B. Breit, Acc. Chem. Res. 56 (2023) 3676–3693. doi: 10.1021/acs.accounts.3c00322
11. [11]
  L. Li, S. Wang, A. Jakhar, et al., Green Synth. Catal. 4 (2023) 124–134. doi: 10.1117/12.2660370
12. [12]
  J.M. Zhang, Z.T. He, Chin. J. Org. Chem. 45 (2025) 592–601. doi: 10.6023/cjoc202406047
13. [13]
  K. Takahashi, A. Miyake, G. Hata, Bull. Chem. Soc. Jpn. 45 (1972) 1183–1191. doi: 10.1246/bcsj.45.1183
14. [14]
  R.W. Armbruster, M.M. Morgan, J.L. Schmidt, et al., Organometallics 5 (1986) 234–237. doi: 10.1021/om00133a011
15. [15]
  P.W. Jolly, N. Kokel, Synthesis 1990 (1990) 771–773. doi: 10.1055/s-1990-27010
16. [16]
  B.M. Trost, L. Zhi, Tetrahedron Lett. 33 (1992) 1831–1834. doi: 10.1016/S0040-4039(00)74154-2
17. [17]
  O. Löber, M. Kawatsura, J.F. Hartwig, J. Am. Chem. Soc. 123 (2001) 4366–4367. doi: 10.1021/ja005881o
18. [18]
  B.M. Trost, C. Jäkel, B. Plietker, J. Am. Chem. Soc. 125 (2003) 4438–4439. doi: 10.1021/ja029190z
19. [19]
  L.M. Lutete, I. Kadota, Y. Yamamoto, J. Am. Chem. Soc. 126 (2004) 1622–1623. doi: 10.1021/ja039774g
20. [20]
  B.M. Trost, J. Xie, J.D. Sieber, J. Am. Chem. Soc. 133 (2011) 20611–20622. doi: 10.1021/ja209244m
21. [21]
  N.J. Adamson, E. Hull, S.J. Malcolmson, J. Am. Chem. Soc. 139 (2017) 7180–7183. doi: 10.1021/jacs.7b03480
22. [22]
  N.J. Adamson, K.C.E. Wilbur, S.J. Malcolmson, J. Am. Chem. Soc. 140 (2018) 2761–2764. doi: 10.1021/jacs.7b13300
23. [23]
  S.Z. Nie, R.T. Davison, V.M. Dong, J. Am. Chem. Soc. 140 (2018) 16450–16454. doi: 10.1021/jacs.8b11150
24. [24]
  Q. Zhang, H. Yu, L. Shen, et al., J. Am. Chem. Soc. 141 (2019) 14554–14559. doi: 10.1021/jacs.9b07600
25. [25]
  Z. Zhang, F. Xiao, H.M. Wu, et al., Org. Lett. 22 (2020) 569–574. doi: 10.1021/acs.orglett.9b04341
26. [26]
  C.I. Onyeagusi, X. Shao, S.J. Malcolmson, Org. Lett. 22 (2020) 1681–1685. doi: 10.1021/acs.orglett.0c00342
27. [27]
  H. Yang, D. Xing, Chem. Commun. 56 (2020) 3721–3724. doi: 10.1039/d0cc00265h
28. [28]
  Q. Zhang, D. Dong, W.W. Zi, J. Am. Chem. Soc. 142 (2020) 15860–15869. doi: 10.1021/jacs.0c05976
29. [29]
  M.M. Li, L. Cheng, L.J. Xiao, et al., Angew. Chem. Int. Ed. 60 (2021) 2948–2951. doi: 10.1002/anie.202012485
30. [30]
  A.Y. Jiu, H.S. Slocumb, C.S. Yeung, et al., Angew. Chem. Int. Ed. 60 (2021) 19660–19664. doi: 10.1002/anie.202105679
31. [31]
  Q. Zhang, M. Zhu, W.W. Zi, Chem 8 (2022) 2784–2796. doi: 10.1016/j.chempr.2022.07.014
32. [32]
  Y.C. Wang, Z.X. Xiao, M. Wang, et al., Angew. Chem. Int. Ed. 62 (2023) e202215568. doi: 10.1002/anie.202215568
33. [33]
  S.Q. Yang, A.J. Han, Y. Liu, et al., J. Am. Chem. Soc. 145 (2023) 3915–3925. doi: 10.1021/jacs.2c11843
34. [34]
  J.M. Zhang, Y.C. Wang, L. Chen, et al., Chem. Eur. J. 30 (2024) e202401350. doi: 10.1002/chem.202401350
35. [35]
  L.M. Lutete, I. Kadota, Y. Yamamoto, J. Am. Chem. Soc. 126 (2004) 1622–1623. doi: 10.1021/ja039774g
36. [36]
  J.T.D. Lee, Y. Zhao, Chem. Eur. J. 24 (2018) 9520–9524. doi: 10.1002/chem.201802273
37. [37]
  M.S. Wu, Z.Y. Han, L.Z. Gong, Org. Lett. 23 (2021) 636–641. doi: 10.1021/acs.orglett.0c03466
38. [38]
  J. Zhang, Y.N. Wang, C. You, et al., Org. Lett. 24 (2022) 1186–1189. doi: 10.1021/acs.orglett.1c04334
39. [39]
  M.Q. Tang, Z.J. Yang, Z.T. He, Nat. Commun. 14 (2023) 6303. doi: 10.1038/s41467-023-42160-2
40. [40]
  Y. Lin, W. Wen, J.H. Liu, et al., Org. Lett. 26 (2024) 7908–7913. doi: 10.1021/acs.orglett.4c02840
41. [41]
  Y. Liu, H. Chen, X. Wang, J. Am. Chem. Soc. 146 (2024) 28427–28436. doi: 10.1021/jacs.4c09983
42. [42]
  Y. Yamamoto, M. Al-Masum, N. Asao, J. Am. Chem. Soc. 116 (1994) 6019–6020. doi: 10.1021/ja00092a083
43. [43]
  B.M. Trost, V.J. Gerusz, J. Am. Chem. Soc. 117 (1995) 5156–5157. doi: 10.1021/ja00123a020
44. [44]
  Y. Yamamoto, M. Al-Masum, Synlett 1995 (1995) 969–970. doi: 10.1055/s-1995-5148
45. [45]
  M. Li, S. Datta, D.M. Barber, et al., Org. Lett. 14 (2012) 6350–6353. doi: 10.1021/ol303128s
46. [46]
  H. Zhou, Y. Wang, L. Zhang, et al., J. Am. Chem. Soc. 139 (2017) 3631–3634. doi: 10.1021/jacs.7b00437
47. [47]
  Z. Wu, M. Zhang, Y. Shi, et al., Org. Chem. Front. 7 (2020) 1502–1511. doi: 10.1039/d0qo00174k
48. [48]
  M. Zhu, Q. Zhang, W.W. Zi, Angew. Chem. Int. Ed. 60 (2021) 6545–6552. doi: 10.1002/anie.202014510
49. [49]
  H.C. Lin, G.J. Knox, C.M. Pearson, et al., Angew. Chem. Int. Ed. 61 (2022) e202201753. doi: 10.1002/anie.202201753
50. [50]
  M. Zhu, P. Wang, Q. Zhang, et al., Angew. Chem. Int. Ed. 61 (2022) e202207621. doi: 10.1002/anie.202207621
51. [51]
  J.H. Liu, Q. Zhou, Y. Lin, et al., ACS Catal. 13 (2023) 6013–6022. doi: 10.1021/acscatal.3c00790
52. [52]
  M.Q. Tang, Z.J. Yang, A.J. Han, et al., Angew. Chem. Int. Ed. 64 (2025) e202413428. doi: 10.1002/anie.202413428
53. [53]
  M.M. Salter, V. Gevorgyan, S. Saito, et al., Chem. Commun. 32 (1996) 17–18.
54. [54]
  V. Gevorgyan, C. Kadowaki, M.M. Salter, et al., Tetrahedron 53 (1997) 9097–9106. doi: 10.1016/S0040-4020(97)00602-9
55. [55]
  U. Radhakrishnan, M. Al-Masum, Y. Yamamoto, Tetrahedron Lett. 39 (1998) 1037–1040. doi: 10.1016/S0040-4039(97)10697-9
56. [56]
  N.J. Adamson, H. Jeddi, S.J. Malcolmson, J. Am. Chem. Soc. 141 (2019) 8574–8583. doi: 10.1021/jacs.9b02637
57. [57]
  H. Tsukamoto, T. Konno, K. Ito, et al., Org. Lett. 21 (2019) 6811–6814. doi: 10.1021/acs.orglett.9b02439
58. [58]
  S.Q. Yang, Y.F. Wang, W.C. Zhao, et al., J. Am. Chem. Soc. 143 (2021) 7285–7291. doi: 10.1021/jacs.1c03157
59. [59]
  L. Li, S. Wang, P. Luo, et al., Nat. Commun. 12 (2021) 5667. doi: 10.1038/s41467-021-25981-x
60. [60]
  Q. Li, X. Fang, R. Pan, et al., J. Am. Chem. Soc. 144 (2022) 11364–11376. doi: 10.1021/jacs.2c03620
61. [61]
  C. You, M. Shi, X. Mi, et al., Nat. Commun. 14 (2023) 2911. doi: 10.1038/s41467-023-38488-4
62. [62]
  M. Eaton, Y. Dai, Z. Wang, et al., J. Am. Chem. Soc. 145 (2023) 21638–21645. doi: 10.1021/jacs.3c08151
63. [63]
  B.Y. Xie, Z.T. He, ACS Catal. 14 (2024) 9742–9751. doi: 10.1021/acscatal.4c02377
64. [64]
  R.C. Larock, Y.D. Lu, A.C. Bain, et al., J. Org. Chem. 56 (1991) 4589–4590. doi: 10.1021/jo00015a002
65. [65]
  R.C. Larock, Y. Wang, Y. Lu, et al., J. Org. Chem. 59 (1994) 8107–8114. doi: 10.1021/jo00105a030
66. [66]
  Y. Wang, X. Dong, R.C. Larock, J. Org. Chem. 68 (2003) 3090–3098. doi: 10.1021/jo026716p
67. [67]
  H. Pang, D. Wu, H. Cong, et al., ACS Catal. 9 (2019) 8555–8560. doi: 10.1021/acscatal.9b02747
68. [68]
  Y. Zhang, H.C. Shen, Y.Y. Li, et al., Chem. Commun. 55 (2019) 3769–3772. doi: 10.1039/c9cc01379b
69. [69]
  D. Zhu, Z. Jiao, Y.R. Chi, et al., Angew. Chem. Int. Ed. 59 (2020) 5341–5345. doi: 10.1002/anie.201915864
70. [70]
  Y.W. Chen, Y. Liu, H.Y. Lu, et al., Nat. Commun. 12 (2021) 5626. doi: 10.1038/s41467-021-25978-6
71. [71]
  Q.Y. Liao, C. Ma, Y.C. Wang, et al., Chin. Chem. Lett. 34 (2023) 108371. doi: 10.1016/j.cclet.2023.108371
72. [72]
  H.Z. Miao, Y. Liu, Y.W. Chen, et al., Synlett 34 (2023) 451–456. doi: 10.1055/a-1916-2937
73. [73]
  X. Wang, H.Z. Miao, G.Q. Lin, Z.T. He, Angew. Chem. Int. Ed. 62 (2023) e202301556. doi: 10.1002/anie.202301556
74. [74]
  X.X. Chen, H. Luo, Y.W. Chen, et al., Angew. Chem. Int. Ed. 62 (2023) e202307628. doi: 10.1002/anie.202307628
75. [75]
  Y.L. Su, L.L. Li, X.L. Zhou, et al., Org. Lett. 20 (2018) 2403–2406. doi: 10.1021/acs.orglett.8b00740
76. [76]
  X. Fang, Q. Li, R. Shi, et al., Org. Lett. 20 (2018) 6084–6088. doi: 10.1021/acs.orglett.8b02481
77. [77]
  L. Liao, R. Jana, K.B. Urkalan, et al., J. Am. Chem. Soc. 133 (2011) 5784–5787. doi: 10.1021/ja201358b
78. [78]
  V. Saini, M.S. Sigman, J. Am. Chem. Soc. 134 (2012) 11372–11375. doi: 10.1021/ja304344h
79. [79]
  M.S. McCammant, T. Shigeta, M.S. Sigman, Org. Lett. 18 (2016) 1792–1795. doi: 10.1021/acs.orglett.6b00517
80. [80]
  D. Wu, H. Pang, G. Yin, Chin. Chem. Lett. 34 (2023) 108087. doi: 10.1016/j.cclet.2022.108087
81. [81]
  R.X. Liang, Y.X. Jia, Acc. Chem. Res. 55 (2022) 734–745. doi: 10.1021/acs.accounts.1c00781
82. [82]
  X.S. Zhang, Y.P. Han, Y. Zhang, et al., Adv. Synth. Catal. 365 (2023) 2436–2466. doi: 10.1002/adsc.202300476
83. [83]
  A.V. Narsaiah, P. Narsimha, Med. Chem. Res. 21 (2012) 538–541. doi: 10.1007/s00044-011-9556-x
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