Citation: Pengwei Tan, Shuyang Shen, Yuanyuan Luo, Guotao Duan. In-situ growth of high-crystallinity M₃(hexaaminotriphenylene)₂ (M = Co, Ni) thin film for field-effect transistor-based glucose biosensor[J]. Chinese Chemical Letters, ;2026, 37(4): 111636. doi: 10.1016/j.cclet.2025.111636 shu

In-situ growth of high-crystallinity M₃(hexaaminotriphenylene)₂ (M = Co, Ni) thin film for field-effect transistor-based glucose biosensor

Pengwei Tan ^{a, 1} ,
Shuyang Shen ^{b, 1} ,
Yuanyuan Luo ^{b, *,} ,
Guotao Duan ^{a, *,}

a.
School of Integrated Circuits, Huazhong University of Science and Technology, Wuhan 430074, China
b.
Key Laboratory of Materials Physics, Institute of Solid State Physics, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China

yyluo@issp.ac.cn

duangt@hust.edu.cn

Received Date: 6 February 2025
Revised Date: 15 July 2025
Accepted Date: 24 July 2025
Available Online: 25 July 2025

Figures(5)

The integration of advanced sensing materials as channel layers in devices is essential for constructing field-effect transistor (FET) biosensors. In this study, we synthesized high-crystallinity bimetallic M₃(hexaaminotriphenylene)₂ (M = Co, Ni) thin films as FET channel materials via an in-situ growth method using a mixed solvent system of water and N,N-dimethylformamide (DMF). This bimetallic metal-organic framework (MOF)-based FET then served as a glucose biosensor, achieving a high sensitivity and an ultra-wide detection range from 10 nmol/L to 10 mmol/L. Further studies reveal that the success of in-situ growth of the high-crystalline bimetallic MOF film can be attributed to the coordination solvent exchange reaction between the metal atomic center, DMF, and water. Furthermore, the introduction of bimetallic centers enhances the number of active sites within the MOF, thereby achieving an ultra-low detection limit and an ultra-wide detection range. This work presents a versatile approach for constructing high performance FET biosensors.
- M₃(hexaaminotriphenylene)₂ (M = Co, Ni) thin film,
- Metal-organic framework (MOF),
- Field-effect transistor (FET),
- Glucose biosensors,
- In-situ growth
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In-situ growth of high-crystallinity M3(hexaaminotriphenylene)2 (M = Co, Ni) thin film for field-effect transistor-based glucose biosensor

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通讯作者: 陈斌, bchen63@163.com

In-situ growth of high-crystallinity M₃(hexaaminotriphenylene)₂ (M = Co, Ni) thin film for field-effect transistor-based glucose biosensor