Citation: Giulia Brufani, Edoardo Bazzica, Yanlong Gu, Francesco Mauriello, Luigi Vaccaro. Csp²–H functionalization as an efficient catalytic route to carbazoles[J]. Chinese Chemical Letters, ;2026, 37(1): 111545. doi: 10.1016/j.cclet.2025.111545 shu

Csp²–H functionalization as an efficient catalytic route to carbazoles

Giulia Brufani ^{a, b, 1} ,
Edoardo Bazzica ^{a, 1} ,
Yanlong Gu ^c ,
Francesco Mauriello ^b ,
Luigi Vaccaro ^{a, *,}

a.
Laboratory of Green S.O.C. – Dipartimento di Chimica, Biologia e Biotecnologie, Università degli Studi di Perugia, Via Elce di Sotto 8, 06123, Perugia, Italy
b.
Department of Civil, Energy, Environmental and Material Engineering (DICEAM), Università degli Studi Mediterranea di Reggio Calabria, via Graziella, Feo di Vito, 89122 Reggio Calabria, Italy
c.
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, Hubei Key Laboratory of Material Chemistry and Service Failure, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China

luigi.vaccaro@unipg.it

Received Date: 21 April 2025
Revised Date: 17 June 2025
Accepted Date: 3 July 2025
Available Online: 11 July 2025

Figures(40)

Given the broad applicability of carbazole structural moieties in materials science and medicinal chemistry, significant efforts have been devoted to developing efficient synthetic catalytic methodologies to access this valuable scaffold. Catalyzed direct Csp²–H functionalization provides an effective and cost-efficient approach to synthesizing carbazoles from simple and readily available starting materials, ensuring a promising path characterized by excellent atom and step economy. This review highlights the substantial progress made in the last 10 years in advancing catalytic Csp²–H functionalization techniques for synthesizing carbazoles.
- C–H functionalization,
- Carbazoles,
- Synthetic methodologies,
- Catalysis
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

Csp2–H functionalization as an efficient catalytic route to carbazoles

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通讯作者: 陈斌, bchen63@163.com

Csp²–H functionalization as an efficient catalytic route to carbazoles