PELSA: A novel method for highly sensitive identification of protein targets and binding regions
-
*Corresponding author.
E-mail address: bfyuan@whu.edu.cn (B.-F. Yuan).
Citation:
Jun Xiong, Bi-Feng Yuan. PELSA: A novel method for highly sensitive identification of protein targets and binding regions[J]. Chinese Chemical Letters,
;2025, 36(12): 111527.
doi:
10.1016/j.cclet.2025.111527
J. Zhu, Y. Xiong, X. Bai, et al., Chin. Chem. Lett. 36 (2025) 110799.
doi: 10.1016/j.cclet.2024.110799
J. Lyu, K. Wang, M. Ye, TrAC Trends Anal. Chem. 124 (2020) 115574.
K. Li, S. Chen, K. Wang, et al., Nat. Methods 22 (2025) 278–282.
doi: 10.1038/s41592-024-02553-7
Y. Ma, Y. Wang, F. Wang, et al., Chin. Chem. Lett. 36 (2025) 110546.
I. Piazza, N. Beaton, R. Bruderer, et al., Nat. Commun. 11 (2020) 4200.
Chunhui Zhang , Jie Wang , Jieyang Zhan , Runmin Yang , Guanggang Gao , Jiayuan Zhang , Linlin Fan , Mengqi Wang , Hong Liu . Highly sensitive hydrazine detection through a novel Raman scattering quenching mechanism enabled by a crystalline and noble metal–free polyoxometalate substrate. Chinese Chemical Letters, 2025, 36(3): 109719-. doi: 10.1016/j.cclet.2024.109719
Xingyu Ma , Yi-Xin Chen , Zi Ye , Chong-Jing Zhang . Isotope-labeled click-free probes to identify protein targets of lysine-targeting covalent reversible molecules. Chinese Chemical Letters, 2025, 36(5): 110203-. doi: 10.1016/j.cclet.2024.110203
Erzhuo Cheng , Yunyi Li , Wei Yuan , Wei Gong , Yanjun Cai , Yuan Gu , Yong Jiang , Yu Chen , Jingxi Zhang , Guangquan Mo , Bin Yang . Galvanostatic method assembled ZIFs nanostructure as novel nanozyme for the glucose oxidation and biosensing. Chinese Chemical Letters, 2024, 35(9): 109386-. doi: 10.1016/j.cclet.2023.109386
Quanxin Ning , Yidan Zhang , Huayi Sun , Xin Zhao , Haodong Zhang , Feng Cui , Xiaochun Xie , Fangman Chen , Wen Sun , Hong Zhang . Light-harvesting pigment-binding protein-mimicking carbon dots for photodynamic therapy. Chinese Chemical Letters, 2025, 36(11): 111133-. doi: 10.1016/j.cclet.2025.111133
Ying Li , Long-Jie Wang , Yong-Kang Zhou , Jun Liang , Bin Xiao , Ji-Shen Zheng . An improved installation of 2-hydroxy-4-methoxybenzyl (iHmb) method for chemical protein synthesis. Chinese Chemical Letters, 2024, 35(5): 109033-. doi: 10.1016/j.cclet.2023.109033
Wu-Jian Long , Yang Yu , Chuang He . A novel and promising engineering application of carbon dots: Enhancing the chloride binding performance of cement. Chinese Chemical Letters, 2024, 35(6): 108943-. doi: 10.1016/j.cclet.2023.108943
Meiling Xu , Xinyang Li , Pengyuan Liu , Junjun Liu , Xiao Han , Guodong Chai , Shuangling Zhong , Bai Yang , Liying Cui . A novel and visible ratiometric fluorescence determination of carbaryl based on red emissive carbon dots by a solvent-free method. Chinese Chemical Letters, 2025, 36(2): 109860-. doi: 10.1016/j.cclet.2024.109860
Xia-Lin Dai , Yu-Hang Yao , Jian-Feng Zhen , Wei Gao , Jia-Mei Chen , Tong-Bu Lu . Reaction crystallization method based on deep eutectic solvents: A novel, green and efficient cocrystal synthesis approach. Chinese Chemical Letters, 2025, 36(11): 110413-. doi: 10.1016/j.cclet.2024.110413
Ting-Ting Huang , Jin-Fa Chen , Juan Liu , Tai-Bao Wei , Hong Yao , Bingbing Shi , Qi Lin . A novel fused bi-macrocyclic host for sensitive detection of Cr2O72− based on enrichment effect. Chinese Chemical Letters, 2024, 35(7): 109281-. doi: 10.1016/j.cclet.2023.109281
Ruikui YAN , Xiaoli CHEN , Miao CAI , Jing REN , Huali CUI , Hua YANG , Jijiang WANG . Design, synthesis, and fluorescence sensing performance of highly sensitive and multi-response lanthanide metal-organic frameworks. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 834-848. doi: 10.11862/CJIC.20230301
Xin Dong , Jing Liang , Zhijin Xu , Huajie Wu , Lei Wang , Shihai You , Junhua Luo , Lina Li . Exploring centimeter-sized crystals of bismuth-iodide perovskite toward highly sensitive X-ray detection. Chinese Chemical Letters, 2024, 35(6): 108708-. doi: 10.1016/j.cclet.2023.108708
Linfang Wang , Jing Liu , Minghao Ren , Wei Guo . A highly sensitive fluorescent HClO probe for discrimination between cancerous and normal cells/tissues. Chinese Chemical Letters, 2024, 35(6): 108945-. doi: 10.1016/j.cclet.2023.108945
Jing REN , Ruikui YAN , Xiaoli CHEN , Huali CUI , Hua YANG , Jijiang WANG . Synthesis and fluorescence sensing of a highly sensitive and multi-response cadmium coordination polymer. Chinese Journal of Inorganic Chemistry, 2025, 41(3): 574-586. doi: 10.11862/CJIC.20240287
Yuwan Lu , Xiaodan Zhang , Yuming Huang . Dual-site Se/NC specific peroxidase-like nanozyme for highly sensitive methimazole detection. Chinese Chemical Letters, 2025, 36(4): 110129-. doi: 10.1016/j.cclet.2024.110129
Feng Shi , Guiling Li , Haibing Zhu , Ling Li , Ming Chen , Juan Li , Huifang Shen , Hao Zeng , Lingfeng Min , Zhanjun Yang . Nanozyme-triggered polymerization amplification strategy for constructing highly sensitive surface plasmon resonance immunosensing. Chinese Chemical Letters, 2025, 36(6): 110333-. doi: 10.1016/j.cclet.2024.110333
Panpan Sun , Qian Li , Ningshuang Gao , Mingyue Luo , Wenzhuo Chang , Baodui Wang , Xiaoquan Lu , Zhonghua Xue . Solid state luminescent-enabled lateral flow immunoassay with highly fluorescence performance for rapid and quantitative detection of C-reactive protein. Chinese Chemical Letters, 2025, 36(10): 110801-. doi: 10.1016/j.cclet.2024.110801
Simin Wei , Yaqing Yang , Junjie Li , Jialin Wang , Jinlu Tang , Ningning Wang , Zhaohui Li . The Mn/Yb/Er triple-doped CeO2 nanozyme with enhanced oxidase-like activity for highly sensitive ratiometric detection of nitrite. Chinese Chemical Letters, 2024, 35(6): 109114-. doi: 10.1016/j.cclet.2023.109114
Dan Zhou , Liangjin Bao , Haoqi Long , Duo Zhou , Yuwei Xu , Bo Wang , Chuanqin Xia , Liang Xian , Chengbin Zheng . Capillary electrophoresis as sample introduction system for highly sensitive and interference-free determination of 99Tc by ICP-MS. Chinese Chemical Letters, 2025, 36(4): 110093-. doi: 10.1016/j.cclet.2024.110093
Bangdi GE , Xiaowei SONG , Zhiqiang LIANG . A bifunctional three-dimensional Eu-MOF fluorescent probe for highly sensitive detection of 2, 4, 6-trinitrophenol and tetracycline. Chinese Journal of Inorganic Chemistry, 2025, 41(10): 2165-2174. doi: 10.11862/CJIC.20250190
Yanwei Duan , Qing Yang . Molecular targets and their application examples for interrupting chitin biosynthesis. Chinese Chemical Letters, 2025, 36(4): 109905-. doi: 10.1016/j.cclet.2024.109905