Citation: Gao-Sheng Zhu, Zhen-Hang Xu, Shao-Zhan Lan, Long Li, Yan-Ying Zheng, Lu Zhang, Qiao-Xia Shang, Bao-Yi Yu, Chong-Chen Wang. Sustainable fungicide delivery via imazalil-functionalized nano-coordination polymer carriers: Enhanced stability, environmental safety, and pH-responsive properties[J]. Chinese Chemical Letters, ;2026, 37(2): 111428. doi: 10.1016/j.cclet.2025.111428 shu

Sustainable fungicide delivery via imazalil-functionalized nano-coordination polymer carriers: Enhanced stability, environmental safety, and pH-responsive properties

Gao-Sheng Zhu ^a ,
Zhen-Hang Xu ^a ,
Shao-Zhan Lan ^a ,
Long Li ^a ,
Yan-Ying Zheng ^a ,
Lu Zhang ^b ,
Qiao-Xia Shang ^a ,
Bao-Yi Yu ^{a, *,} ,
Chong-Chen Wang ^{b, *,}

a.
Key Laboratory of Urban Agriculture in North China, Ministry of Agriculture and Rural Affairs, College of Bioscience and Resources Environment, Beijing University of Agriculture, Beijing 102206, China
b.
Institute of Advanced Materials/Beijing Key Laboratory of Functional Materials for Building Structure and Environment Remediation, Beijing University of Civil Engineering and Architecture, Beijing 100044, China

baoyi.yu@bua.edu.cn

wangchongchen@bucea.edu.cn

Received Date: 2 February 2025
Revised Date: 2 June 2025
Accepted Date: 8 June 2025
Available Online: 8 June 2025

Figures(5)

The preparation of a novel nanoscale imazalil (IMZ)-based coordination polymer [Zn(HBTC)(IMZ)₂]_n (PDCP1) (H₃BTC = 1,3,5-benzenetricarboxylic acid), and its antifungal application within a sustainable delivery system was reported. The intermolecular interactions presented in the structure, and their contributions to crystal packing were studied by Hirshfeld, Fingerprint plot and Mayer bond order. The obtained PDCP1 had a relatively high loading rate of IMZ (68.5%). PDCP1 exhibited notable antifungal activities against Colletotrichum gloeosporioides, Magnaporthe Oryzae, and Alternaria Nees strains, with EC₅₀ values of 0.72, 0.92, and 0.56 µg/mL, respectively. The key benefits of the application of PDCP1 as a control release pesticide include high fungicide loading and offer nearly complete release, pH-responsive release, enhanced UV stability, exhibits favorable biosafety profiles. The remarkable inhibition of C. gloeosporioides growth by PDCP1 underscores a promising strategy for agrochemical material development, high loading of active ingredients and readily delivery fosters more efficient pesticides utilization in agricultural processes.
- Nano-fungicide,
- Fungicide release,
- Antifungal activity,
- CP fungicide,
- Imazalil
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