Citation: Haokun Yuan, Anjing Liao, Shunhong Chen, Yiming Tian, Yaming Liu, Jian Wu. Pyrimidine derivatives in discovery of pesticides: A review[J]. Chinese Chemical Letters, ;2026, 37(2): 111305. doi: 10.1016/j.cclet.2025.111305 shu

Pyrimidine derivatives in discovery of pesticides: A review

State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China

jwu6@gzu.edu.cn

Received Date: 17 January 2025
Revised Date: 30 April 2025
Accepted Date: 12 May 2025
Available Online: 12 May 2025

Figures(9)

Pyrimidine is a widely used compound in pesticides and medicine, with over 60 commercial pesticides containing a pyrimidine structure. Examples include the insecticide flufenerim, herbicide nicosulfuron, fungicide mepanipyrim, antiviral agent ningnanmycin, and plant growth regulator ancymidol. This paper reviews the characteristics from 2014 to 2024 of highly active pyrimidine-containing compounds and their biological activities, focusing on insecticidal, herbicidal, antibacterial, antiviral, and plant growth regulation properties. The goal is to provide insights for the design and synthesis of new pyrimidine-based pesticide candidates.
- Pyrimidine compounds,
- Insecticidal activity,
- Herbicidal activity,
- Antifungicidal activity,
- Antiviral activity,
- Plant growth regulator
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沈阳化工大学材料科学与工程学院沈阳 110142