Citation: Menglin Zhou, Lin Zhang, Xuefei Shan, Fengqin Chang, Wentong Chen, Xuguang An, Guangzhi Hu. Hydrangea-like B/N co-doped carbon-based electrochemical sensors for the efficient and sensitive detection of aristolochic acid in Aristolochia[J]. Chinese Chemical Letters, ;2025, 36(12): 111073. doi: 10.1016/j.cclet.2025.111073 shu

Hydrangea-like B/N co-doped carbon-based electrochemical sensors for the efficient and sensitive detection of aristolochic acid in Aristolochia

Menglin Zhou ^{a, 1} ,
Lin Zhang ^{a, 1} ,
Xuefei Shan ^a ,
Fengqin Chang ^a ,
Wentong Chen ^b ,
Xuguang An ^c ,
Guangzhi Hu ^{a, *,}

a.
Qilu Lake Field Scientific Observation and Research Station for Plateau Shallow Lake in Yunnan Province, Yunnan Key Laboratory of Ecological Protection and Resource Utilization of River-lake Networks, School of Ecology and Environmental Science, Yunnan University, Kunming 650504, China
b.
Key Laboratory of Coordination Chemistry of Jiangxi Province, School of Chemistry and Chemical Engineering, Jinggangshan University, Ji'an 343009, China
c.
School of Mechanical Engineering, Chengdu University, Chengdu 610106, China

guangzhihu@ynu.edu.cn

Received Date: 19 November 2024
Revised Date: 18 January 2025
Accepted Date: 11 March 2025
Available Online: 12 March 2025

Figures(5)

A novel hydrangea-like boron and nitrogen co-doped carbon material synthesised by the cross-linking reaction of spiny spherical polymers and co-doped with boron and nitrogen (B/N) via high-temperature calcination was used to construct an electrochemical sensor for the detection of aristolochic acid. Under optimal conditions, the sensor showed good electrochemical response to aristolochic acid, with a theoretical detection limit of 47.3 nmol/L and the sensitivity reaching 0.31 µA L µmol^-1 cm^-2. Moreover, the sensor was successfully applied to the detection of aristolochic acid in the extracts of Chinese herbal medicine samples, and the detection results were consistent with those of high-performance liquid chromatography. With a strong selectivity for substances to be measured in complex environments, this study provides a new and efficient method by which to detect aristolochic acid in Chinese herbal medicine, which greatly expands the application field of B/N heteroatom-doped carbon materials.
- Electrochemical sensors,
- Aristolochic acid,
- Electroanalysis,
- Hydrangea-like B/N co-doped carbon,
- Chinese herbal medicine detection
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