Citation: Dayang Xie, Qiannan Cao, Huapan Fang, Yanhui Li, Huayu Tian. Applications and challenges of biomedical polymer materials in pulmonary diseases[J]. Chinese Chemical Letters, ;2026, 37(2): 111032. doi: 10.1016/j.cclet.2025.111032 shu

Applications and challenges of biomedical polymer materials in pulmonary diseases

Dayang Xie ^{a, b, 1} ,
Qiannan Cao ^{b, 1} ,
Huapan Fang ^{b, c, *,} ,
Yanhui Li ^{a, *,} ,
Huayu Tian ^{b, *,}

a.
School of Materials Science and Engineering, Xiamen University of Technology, Xiamen 361024, China
b.
State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), Xiamen University, Xiamen 361005, China
c.
Shenzhen Research Institute of Xiamen University, Shenzhen 518000, China

hpfang@xmu.edu.cn

liyanhui@ciac.ac.cn

thy@xmu.edu.cn

Received Date: 18 November 2024
Revised Date: 2 March 2025
Accepted Date: 3 March 2025
Available Online: 4 March 2025

Figures(13)

Pulmonary diseases have long posed a severe threat to human life and health. The incidence and mortality rates of pulmonary diseases have shown a rising trend year by year, highlighting the urgency of developing safe and effective therapeutic approaches. In recent years, to address the challenges faced by traditional treatment strategies for pulmonary diseases, the interdisciplinary integration has greatly promoted the rapid development of biomedical polymer materials in the field of pulmonary disease treatment. This review provides a detailed description of the structural characteristics of lung tissue, types of pulmonary diseases, traditional treatment methods, the categories and properties of biomedical polymer materials applied to pulmonary diseases. We systematically elaborate on the applications of biomedical polymer materials in the treatment of different pulmonary diseases and thoroughly discuss their functional roles in pulmonary diseases, particularly in the delivery of therapeutic agents to diseased sites, the formation of pulmonary aerosol formulations, and the facilitation of the effective accumulation of therapeutic agents. The latest research progresses of biomedical polymer materials are also introduced in pulmonary disease treatment. We have highlighted the current challenges and development opportunities of biomedical polymer materials in the treatment of pulmonary diseases, and provide future research directions for biomedical polymer materials in this field. This review will provide valuable reference for the basic research and clinical application of biomedical polymer materials in pulmonary disease treatment.
- Pulmonary disease,
- Biomedical polymer materials,
- Lung structure,
- Drug delivery,
- Treatment methods
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沈阳化工大学材料科学与工程学院沈阳 110142