Citation: Yuyao Guan, Baoting Yu, Jun Ding, Tingting Sun, Zhigang Xie. BODIPY photosensitizers for antibacterial photodynamic therapy[J]. Chinese Chemical Letters, ;2025, 36(8): 110645. doi: 10.1016/j.cclet.2024.110645 shu

BODIPY photosensitizers for antibacterial photodynamic therapy

Yuyao Guan ^a ,
Baoting Yu ^a ,
Jun Ding ^{a, *,} ,
Tingting Sun ^{b, *,} ,
Zhigang Xie ^b

a.
Department of Radiology, China−Japan Union Hospital of Jilin University, Changchun 130033, China
b.
Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

dingjun@jlu.edu.cn

suntt@ciac.ac.cn

Received Date: 6 September 2024
Revised Date: 4 November 2024
Accepted Date: 11 November 2024
Available Online: 12 November 2024

Figures(13)

Bacterial infections pose a significant threat to human health and entail substantial economic losses. Due to the broad-spectrum antibacterial effect and low susceptibility to drug resistance, photodynamic therapy (PDT), a nontraditional antibacterial approach, has garnered a lot of attention. In PDT, the selection of photosensitizer (PS) is crucial because it directly affects the efficiency and safety of the treatment. As a versatile fluorophore, the advantages of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) used as a PS for antibacterial PDT are mainly reflected in its high quantum yield of singlet oxygen, easy modification, and exceptional photostability. Through strategic chemical modifications of the BODIPY structures, it is possible to enhance their photodynamic antibacterial activity and refine their selectivity for bacterial killing. This review focuses on the application of BODIPY-based PSs for treating bacterial infections. According to the design strategies of photodynamic antibacterial materials incorporating BODIPY, a variety of representative therapeutic agents having emerged in recent years are classified and discussed, aiming to offer insights for future research and development in this field.
- BODIPY,
- Photodynamic therapy,
- Antibacterial,
- Antimicrobial,
- Reactive oxygen species
1. [1]
  Y.H. Yan, Y.Z. Li, Z.W. Zhang, et al., Colloids Surf. B: Biointerfaces 202 (2021) 111682.
2. [2]
  Y.W. Ren, H.P. Liu, X.M. Liu, et al., Cell Rep. Phys. Sci. 1 (2020) 100245.
3. [3]
  Y.C. Tian, R. Zhang, B.B. Guan, et al., Pharmaceutics 13 (2021) 1399.
4. [4]
  M. Blondel, C. Machet, B. Wildemann, Y. Abidine, P. Swider, J. Orthop. Res. 42 (2024) 1861–1869. doi: 10.1002/jor.25822
5. [5]
  D. Nicolotti, S. Grossi, V. Palermo, et al., Crit. Care 28 (2024) 44.
6. [6]
  R. Martin-Mateos, L. Martínez-Arenas, Á. Carvalho-Gomes, et al., J. Hepatol. 80 (2024) 904–912.
7. [7]
  G.H. Liu, R.C. Ma, P. Liu, K. Wang, K.Y. Cai, J. Colloid Interface Sci. 655 (2024) 809–821.
8. [8]
  X.Y. Li, D.D. Xing, Y.J. Bai, et al., Biomed. Mater. 19 (2024) 025028.
9. [9]
  P. Xue, R. Sang, N. Li, et al., Front. Cell. Infect. Microbiol. 13 (2023) 1119037.
10. [10]
  O.M. Abdallah, H.R. Shebl, E. Abdelsalam, S.I. Mehrez, World J. Microbiol. Biotechnol. 40 (2024) 72.
11. [11]
  W.T. Wang, Y.Z. Chen, Y.T. Chen, et al., Microbiol. Spectrum 12 (2024) e0127923.
12. [12]
  L.H. Zhou, Y.Y. Wu, X.Q. Meng, et al., Small 14 (2018) e1801008.
13. [13]
  V.N. Nguyen, Z. Zhao, B.Z. Tang, J. Yoon, Chem. Soc. Rev. 50 (2022) 3324–3340. doi: 10.1039/d1cs00647a
14. [14]
  Y. Liu, Y.H. Wang, S.Y. Song, H.J. Zhang, Natl. Sci. Rev. 9 (2022) nwab139.
15. [15]
  Q.Y. Zheng, X.M. Liu, Y.F. Zheng, et al., Chem. Soc. Rev. 50 (2021) 5086–5125. doi: 10.1039/d1cs00056j
16. [16]
  G.N. Zhang, Z.Z. Wu, Y.Q. Yang, et al., Chem. Eng. J. 428 (2022) 131155.
17. [17]
  J.P. Shi, J. Li, Y. Wang, C.Y. Zhang, Chem. Eng. J. 431 (2022) 133714.
18. [18]
  A. Maleki, J. He, S. Bochani, et al., ACS Nano 15 (2021) 18895–18930. doi: 10.1021/acsnano.1c08334
19. [19]
  C.Y. Mao, Y.M. Xiang, X.M. Liu, et al., ACS Appl. Mater. Interfaces 11 (2019) 17902–17914. doi: 10.1021/acsami.9b05787
20. [20]
  A. Alabugin, Photochem. Photobiol. 95 (2019) 722–732. doi: 10.1111/php.13068
21. [21]
  D.P. Chen, Q. Yu, X. Huang, et al., Small 16 (2020) 2001059.
22. [22]
  D.P. Chen, Q. Xu, W.J. Wang, et al., Small 17 (2021) e2006742.
23. [23]
  J.Y. Liu, Y. Tian, L. Dong, RSC Adv. 14 (2024) 8735–8739. doi: 10.1039/d4ra00041b
24. [24]
  R.Z. Zhang, K.K. Niu, Y.S. Bi, et al., Green Chem. 26 (2024) 2241–2247. doi: 10.1039/d3gc04412b
25. [25]
  R.Z. Dong, X.H. Shi, X.D. Wang, et al., Mol. Catal. 553 (2024) 113749.
26. [26]
  X.J. Cai, J. Tian, J.W. Zhu, et al., Chem. Eng. J. 426 (2021) 131919.
27. [27]
  H. Chen, S.L. Li, M. Wu, et al., Angew. Chem. Int. Ed. 59 (2020) 632–636. doi: 10.1002/anie.201907343
28. [28]
  X.L. Sun, J. Sun, Y. Sun, et al., Adv. Funct. Mater. 31 (2021) 2101040.
29. [29]
  L.G. Ding, S. Wang, B.J. Yao, et al., Adv. Healthc. Mater. 10 (2021) 2001821.
30. [30]
  A. Turksoy, D. Yildiz, E.U. Akkaya, Coord. Chem. Rev. 379 (2019) 47–64.
31. [31]
  J. Tian, B.X. Huang, M.H. Nawaz, W.A. Zhang, Coord. Chem. Rev. 420 (2020) 213410.
32. [32]
  A.K. Pujari, R. Kaur, Y.N. Reddy, et al., J. Med. Chem. 67 (2024) 2004–2018. doi: 10.1021/acs.jmedchem.3c01841
33. [33]
  X. Li, B.D. Zheng, X.H. Peng, et al., Coord. Chem. Rev. 379 (2019) 147–160.
34. [34]
  M. Wainwright, A. McLean, Dyes Pigm. 136 (2017) 590–600.
35. [35]
  K. Bilici, S. Cetin, E. Aydındogan, H.Y. Acar, S. Kolemen, Front. Chem. 9 (2021) 707876.
36. [36]
  M. Maia, D.I.S.P. Resende, F. Durães, M.M.M. Pinto, E. Sousa, Eur. J. Med. Chem. 210 (2021) 113085.
37. [37]
  J. Wang, C.J. Yu, E.H. Hao, L.J. Jiao, Coord. Chem. Rev. 470 (2022) 214709.
38. [38]
  N.A. Bumagina, E.V. Antina, A.A. Ksenofontov, et al., Coord. Chem. Rev. 469 (2022) 214684.
39. [39]
  Z.Y. Wang, X. Guo, Z.X. Kang, et al., Org. Lett. 25 (2023) 744–749.
40. [40]
  F. Lv, X. Guo, Z.Y. Li, et al., Dyes Pigm. 210 (2023) 111030.
41. [41]
  F. Lv, H. Li, Q.H. Wu, et al., Chem. Commun. 58 (2022) 3937–3940. doi: 10.1039/d2cc00297c
42. [42]
  R.B. Liu, Y. Qian, Spectrochim. Acta. A Mol. Biomol. Spectrosc. 304 (2024) 123387.
43. [43]
  C. Kim, D.K. Mai, W.J. Kim, et al., Biomater. Sci. 12 (2024) 1536–1548. doi: 10.1039/d3bm01520c
44. [44]
  X. Chen, B.B. Mendes, Y.H. Zhuang, et al., J. Am. Chem. Soc. 146 (2024) 1644–1656. doi: 10.1021/jacs.3c12416
45. [45]
  X. Guo, J.M. Yang, M. Li, et al., Angew. Chem. Int. Ed. 61 (2022) e202211081.
46. [46]
  Z.Q. Mao, J.H. Kim, J. Lee, et al., Coord. Chem. Rev. 476 (2023) 1–34.
47. [47]
  B.W. Lu, X. Lu, M.M. Mu, et al., Heliyon 10 (2024) e26907.
48. [48]
  T. Tao, X. Hu, D. Sun, et al., Dyes Pigm. 224 (2024) 111996.
49. [49]
  M. Hu, X.C. Dong, W.L. Zhao, Bioorg. Med. Chem. 99 (2024) 117583.
50. [50]
  P. Sen, A. Sindelo, N. Nnaji, J. Mack, T. Nyokong, Photochem. Photobiol. 99 (2022) 947–956.
51. [51]
  Q.H. Wu, H. Wen, W.H. Lin, T.T. Sun, Z.G. Xie, Chin. Chem. Lett. 35 (2024) 109692.
52. [52]
  O. Santoro, M.C. Malacarne, F. Sarcone, et al., Int. J. Mol. Sci. 24 (2023) 4340. doi: 10.3390/ijms24054340
53. [53]
  D. Navarro-Barreda, R. de Llanos, J.F. Miravet, et al., J. Photochem. Photobiol. B 235 (2022) 112543.
54. [54]
  S. Kirar, Y.N. Reddy, U. Chand Banerjee, J. Bhaumik, ChemPhotoChem 7 (2022) e202200172.
55. [55]
  J. Wang, Q.B. Gong, L.J. Jiao, E.H. Hao, Coord. Chem. Rev. 496 (2023) 215367.
56. [56]
  A.M. Durantini, D.A. Heredia, J.E. Durantini, E.N. Durantini, Eur. J. Med. Chem. 144 (2018) 651–661.
57. [57]
  M.L. Agazzi, M.B. Ballatore, A.M. Durantini, E.N. Durantini, A.C. Tomé, J. Photochem. Photobiol. C 40 (2019) 21–48.
58. [58]
  C.N. Li, Y.T. Li, Q.H. Wu, T.T. Sun, Z.G. Xie, Biomater. Sci. 9 (2021) 7648–7654. doi: 10.1039/d1bm01384j
59. [59]
  H. Wen, Q.H. Wu, L.Q. Liu, et al., Biomater. Sci. 11 (2023) 2870–2876. doi: 10.1039/d3bm00073g
60. [60]
  G.Y. Lin, M. Hu, R. Zhang, et al., J. Med. Chem. 64 (2021) 18143–18157. doi: 10.1021/acs.jmedchem.1c01643
61. [61]
  C.J. Mou, X.Y. Wang, Y.C. Liu, Z.G. Xie, M. Zheng, J. Mater. Chem. B 10 (2022) 8094–8099. doi: 10.1039/d2tb01539k
62. [62]
  X.N. Liang, L. Xia, Y.C. Zhu, et al., Biomater. Sci. 10 (2022) 4235–4242. doi: 10.1039/d2bm00780k
63. [63]
  Y.C. Liu, M. Zheng, Food Chem. 427 (2023) 136691.
64. [64]
  Z.Q. Shen, L.L. Qu, X.L. Kan, et al., Colloids Surf. A 644 (2022) 128835.
65. [65]
  S.S. Zhao, X.P. Guo, X.H. Pan, Y.B. Huang, R. Cao, Chem. Eng. J. 457 (2023) 141017.
66. [66]
  H. Wen, Q.H. Wu, C.N. Li, T.T. Sun, Z.G. Xie, ACS Appl. Nano Mater. 5 (2022) 1500–1507. doi: 10.1021/acsanm.1c04143
67. [67]
  B.K. Liu, J. Zheng, H. Wang, L.Y. Niu, Q.Z. Yang, Mater. Chem. Front. 7 (2023) 5879–5890. doi: 10.1039/d3qm00753g
68. [68]
  W.T. Lei, Q.H. Wu, H. Wen, et al., J. Mater. Chem. B 11 (2023) 6853–6858. doi: 10.1039/d3tb00684k
69. [69]
  J.K. Gao, H.F. Jiang, P.W. Chen, R.S. Zhang, N. Liu, Bioorg. Chem. 136 (2023) 106554.
70. [70]
  A.G. Robertson, L.M. Rendina, Chem. Soc. Rev. 50 (2021) 4231–4244. doi: 10.1039/d0cs01075h
71. [71]
  P. Bhutani, G. Joshi, N. Raja, et al., J. Med. Chem. 64 (2021) 2339–2381. doi: 10.1021/acs.jmedchem.0c01786
72. [72]
  Y.P. Wu, S.M. Li, Y.C. Chen, W.J. He, Z.J. Guo, Chem. Sci. 13 (2022) 5085–5106. doi: 10.1039/d1sc05478c
73. [73]
  N.M. Amal, M. Shiddiq, B. Armynah, D. Tahir, Luminescence 37 (2022) 2006–2017. doi: 10.1002/bio.4388
74. [74]
  M. Garren, P. Maffe, A. Melvin, et al., ACS Appl. Mater. Interfaces 13 (2021) 56931–56943. doi: 10.1021/acsami.1c17248
75. [75]
  R. Devine, M. Douglass, M. Ashcraft, N. Tayag, H. Handa, ACS Appl. Mater. Interfaces 13 (2021) 19613–19624. doi: 10.1021/acsami.1c01330
76. [76]
  H.J. Wang, Y. Wang, W.H. Xu, et al., ACS Appl. Mater. Interfaces 15 (2023) 54266–54279. doi: 10.1021/acsami.3c10862
77. [77]
  C.Y. Qi, J. Chen, Y. Zhuang, et al., Int. J. Pharm. 640 (2023) 123014.
78. [78]
  C. Farah, L.Y.M. Michel, J.L. Balligand, Nat. Rev. Cardiol. 15 (2018) 292–316. doi: 10.1038/nrcardio.2017.224
79. [79]
  Y.F. Zhao, C. Li, S. Zhang, et al., Front. Microbiol. 14 (2023) 1277552.
80. [80]
  M.Y. He, D.P. Wang, Y.M. Xu, et al., Pharmaceutics 14 (2022) 1345.
81. [81]
  A. Olah, B.A. Barta, M. Ruppert, et al., Eur. Heart J. 44 (2023) 1965 ehad655-.
82. [82]
  J.K. Jiang, J.L. Xie, L. Zhou, et al., Chem. Eng. J. 480 (2024) 147850.
83. [83]
  S.Y. Tao, J. Cheng, G. Su, et al., Angew. Chem. Int. Ed. 59 (2020) 21864–21869. doi: 10.1002/anie.202010009
84. [84]
  R. Ren, D.H. Bremner, W.L. Chen, et al., Int. J. Biol. Macromol. 238 (2023) 124087.
85. [85]
  D. Gao, S. Asghar, R.F. Hu, et al., Acta Pharm. Sin. B 13 (2023) 1498–1521.
86. [86]
  H.N. Tian, J.Y. Lin, F.K. Zhu, et al., Chin. Chem. Lett. 34 (2023) 107577.
87. [87]
  V.A. Zaborova, A.V. Butenko, A.B. Shekhter, et al., Med. Gas Res. 13 (2023) 128–132. doi: 10.4103/2045-9912.344983
88. [88]
  Y.T. Duan, K.W. He, G.Y. Zhang, J.M. Hu, Biomacromolecules 22 (2021) 2160–2170. doi: 10.1021/acs.biomac.1c00251
89. [89]
  M.M. Wan, H. Chen, Q. Wang, et al., Nat. Commun. 10 (2019) 966.
90. [90]
  L. Wang, S.X. Li, J.X. Yin, et al., Nano Lett. 20 (2020) 5036–5042. doi: 10.1021/acs.nanolett.0c01196
91. [91]
  A. Galstyan, R. Schiller, U. Dobrindt, Angew. Chem. Int. Ed. 56 (2017) 10362–10366. doi: 10.1002/anie.201703398
92. [92]
  S.S. Liu, B.N. Wang, Y.W. Yu, et al., ACS Nano 16 (2022) 9130–9141. doi: 10.1021/acsnano.2c01206
93. [93]
  L. Liu, X.Y. Wang, S.X. Zhu, et al., Chem. Mater. 32 (2019) 438–447.
94. [94]
  H.L. Zhou, D.S. Tang, X.X. Kang, et al., Adv. Sci. 9 (2022) 2200732.
95. [95]
  C. Zhao, X. Wang, L. Yu, et al., Acta Biomater. 138 (2022) 528–544.
96. [96]
  S.M. Wu, C. Xu, Y.W. Zhu, et al., Adv. Funct. Mater. 31 (2021) 2103591.
97. [97]
  D.K. Joshi, F. Betancourt, A. McAdorey, et al., J. Photochem. Photobiol. A 434 (2023) 114213.
98. [98]
  Q.X. Shi, C.J. Mou, Z.G. Xie, M. Zheng, Photodiagn. Photodyn. Ther. 39 (2022) 102901.
99. [99]
  V.T. Orlandi, E. Martegani, F. Bolognese, E. Caruso, Photochem. Photobiol. Sci. 21 (2022) 1233–1248. doi: 10.1007/s43630-022-00212-4
100. [100]
  H. Eserci Gürbüz, E. Öztürk Gündüz, M. Bat-Ozmatara, A. Şenocak, E. Okutan, J. Photochem. Photobiol. A 443 (2023) 114890.
101. [101]
  H. Eserci, M. Çetin, F. Aydınoğlu, E.T. Eçik, E. Okutan, J. Mol. Struct. 1265 (2022) 133440.
102. [102]
  C. Kromer, K. Schwibbert, S. Radunz, et al., Front. Microbiol. 14 (2023) 1274715.
103. [103]
  B.L. Carpenter, F. Scholle, H. Sadeghifar, et al., Biomacromolecules 16 (2015) 2482–2492. doi: 10.1021/acs.biomac.5b00758
104. [104]
  J. Piskorz, W. Porolnik, M. Kucinska, et al., ChemMedChem 16 (2021) 399–411. doi: 10.1002/cmdc.202000529
105. [105]
  Y.B. Palacios, S.C. Santamarina, J. Durantini, et al., J. Photochem. Photobiol. B 212 (2020) 112049.
106. [106]
  Y.Y. Bai, Y.Q. Hu, Y.C. Gao, et al., ACS Appl. Mater. Interfaces 13 (2021) 33790–33801. doi: 10.1021/acsami.1c04996
107. [107]
  S. Mansoor, O. Ali Wani, J.K. Lone, et al., Antioxidants 11 (2022) 225. doi: 10.3390/antiox11020225
108. [108]
  R. Singh, S. Singh, P. Parihar, et al., Front. Plant Sci. 7 (2016) 1299.
109. [109]
  M.S. Katarzyna, W. Natalia, N. Klaudia, et al., Antioxidants 9 (2020) 199.
110. [110]
  J.J. Zhang, Y.J. Li, M.L. Jiang, et al., ACS Biomater. Sci. Eng. 9 (2023) 821–830. doi: 10.1021/acsbiomaterials.2c01539
111. [111]
  S.M. Wu, W.Z. Zhang, C.R. Li, et al., Chem. Sci. 15 (2024) 5973–5979. doi: 10.1039/d3sc06976a
112. [112]
  Y.M. Zhang, S.C. Li, J. Wang, et al., J. Mater. Chem. B 12 (2024) 1372–1378. doi: 10.1039/d3tb02623j
113. [113]
  C. Liu, X. Ji, Z.l. Yu, et al., J. Med. Chem. 66 (2023) 7205–7220. doi: 10.1021/acs.jmedchem.2c01653
114. [114]
  Y.N. Sun, C.S. Dong, D.X. Zhang, et al., Dyes Pigm. 228 (2024) 112213.
115. [115]
  L.L. Cao, Y.K. Li, D.X. Zhang, et al., Chin. Chem. Lett. 35 (2024) 109735.
116. [116]
  Z.Z. Yong, B.X. Wen, Q.Q. Dou, et al., Dyes Pigm. 219 (2023) 111614.
117. [117]
  X.H. Ruan, M. Wei, X.Y. He, et al., Colloids Surf. B 231 (2023) 113547.
118. [118]
  D.P. Chen, Z.H. Zhong, Q.L. Ma, et al., ACS Appl. Mater. Interfaces 12 (2020) 26914–26925. doi: 10.1021/acsami.0c05021
119. [119]
  S. Song, G.C. Xu, N. Yang, et al., J. Mater. Sci. 57 (2022) 21206–21218. doi: 10.1007/s10853-022-07924-z
120. [120]
  Q. Yu, X. Huang, T. Zhang, et al., Chem. Res. Chin. Univ. 37 (2021) 951–959.
121. [121]
  X.Y. Wang, L.J. Chen, S.Y. Chong, et al., Nat. Chem. 10 (2018) 1180–1189. doi: 10.1038/s41557-018-0141-5
122. [122]
  D. Thakur, Q.T.H. Ta, J.S. Noh, ACS Appl. Nano Mater. 5 (2022) 1533–1541. doi: 10.1021/acsanm.1c04254
123. [123]
  G.F. Su, S.F. Qiu, J.Q. Lin, et al., Colloids Surf. A 640 (2022) 128414.
124. [124]
  G. Gupta, Y. Sun, A. Das, P.J. Stang, C.Y. Lee, Coord. Chem. Rev. 452 (2022) 214308.
125. [125]
  D.M. Chen, G.Q. He, Q.Y. Chen, et al., New J. Chem. 47 (2023) 8152–8160. doi: 10.1039/d3nj00397c
126. [126]
  X.L. Hu, L.Y. Chu, X.J. Dong, et al., Adv. Funct. Mater. 29 (2019) 1806981.
127. [127]
  Y.Q. Wang, Y.Y. Jin, W. Chen, et al., Chem. Eng. J. 358 (2019) 74–90. doi: 10.1364/dp.2019.74
128. [128]
  Q. Guan, L.L. Zhou, Y.A. Li, et al., ACS Nano 13 (2019) 13304–13316. doi: 10.1021/acsnano.9b06467
129. [129]
  X. Chang, M.B. Qarai, F.C. Spano, J. Chem. Phys. 157 (2022) 209901.
130. [130]
  J. Wang, X.M. Zhang, N. Wang, et al., ACS Appl. Nano Mater. 6 (2023) 16716–16729. doi: 10.1021/acsanm.3c02922
131. [131]
  T. Zhang, C. Ma, T.T. Sun, Z.G. Xie, Coord. Chem. Rev. 390 (2019) 76–85.
132. [132]
  F.F. An, J.Q. Xin, C.T. Deng, et al., J. Mater. Chem. B 9 (2021) 9308–9315. doi: 10.1039/d1tb01883c
133. [133]
  Q.X. Shi, X.Y. Wang, H.X. Liu, Z.G. Xie, M. Zheng, J. Photochem. Photobiol. B 241 (2023) 112674.
134. [134]
  H.Y. Wang, C.N. Li, Q.H. Wu, et al., J. Mater. Chem. B 10 (2022) 4967–4973. doi: 10.1039/d2tb00778a
135. [135]
  C.N. Li, W.H. Lin, S. Liu, T.T. Sun, Z.G. Xie, Mater. Chem. Front. 5 (2021) 284–292. doi: 10.1039/d0qm00624f
136. [136]
  S.W. Wang, W.B. Wu, P. Manghnani, et al., ACS Nano 13 (2019) 3095–3105. doi: 10.1021/acsnano.8b08398
137. [137]
  D.S. Zhang, L.Y. Peng, K.X. Teng, et al., ACS Mater. Lett. 5 (2023) 180–188.
138. [138]
  Y.F. Kang, W.K. Chen, K.X. Teng, et al., CCS Chem. 4 (2022) 3516–3528. doi: 10.31635/ccschem.021.202101600
139. [139]
  J.X. Zhang, S. Mukamel, J. Jiang, J. Phys. Chem. B. 124 (2020) 2238–2244. doi: 10.1021/acs.jpcb.0c00654
140. [140]
  X. Wang, B. Yang, L.X. Li, et al., Theranostics 11 (2021) 7896–7910. doi: 10.7150/thno.61337
141. [141]
  J. Lv, H. Wang, G.Y. Rong, Y.Y. Cheng, Acc. Chem. Res. 55 (2022) 722–733. doi: 10.1021/acs.accounts.1c00766
142. [142]
  B.W. Jiang, D.Y. Hao, C.N. Li, et al., J. Mater. Chem. B 9 (2021) 9971–9979. doi: 10.1039/d1tb02165f
143. [143]
  C. Zhang, T.Q. Liu, W.Q. Wang, et al., ACS Nano 14 (2020) 7425–7434. doi: 10.1021/acsnano.0c02954
144. [144]
  X.Y. Wang, B.W. Jiang, Z.G. Xie, M. Zheng, Colloids Surf. B 220 (2022) 112966.
1. [1]
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2. [2]
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3. [3]
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4. [4]
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5. [5]
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6. [6]
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7. [7]
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8. [8]
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9. [9]
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10. [10]
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11. [11]
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12. [12]
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13. [13]
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14. [14]
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15. [15]
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16. [16]
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17. [17]
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18. [18]
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19. [19]
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20. [20]
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沈阳化工大学材料科学与工程学院沈阳 110142