Citation: Jiaxu Wang, Jinxie Zhang, Xiuping Wang, Jingying Wang, Lina Chen, Jiahui Cao, Wei Cao, Siyu Liang, Ping Luan, Ke Zheng, Xiao-Kun Ouyang, Li Gao, Xiaowen Ou, Fan Zhang, Meitong Ou, Lin Mei. CaCO₃-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release[J]. Chinese Chemical Letters, ;2024, 35(12): 109697. doi: 10.1016/j.cclet.2024.109697 shu

CaCO₃-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release

Jiaxu Wang ^{a, b, 1} ,
Jinxie Zhang ^{a, 1} ,
Xiuping Wang ^{b, 1} ,
Jingying Wang ^{a, b} ,
Lina Chen ^b ,
Jiahui Cao ^a ,
Wei Cao ^a ,
Siyu Liang ^c ,
Ping Luan ^d ,
Ke Zheng ^e ,
Xiao-Kun Ouyang ^f ,
Li Gao ^g ,
Xiaowen Ou ^a ,
Fan Zhang ^{a, *,} ,
Meitong Ou ^{a, *,} ,
Lin Mei ^{a, *,}

a.
State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Biomedical Materials, Key Laboratory of Biomaterials and Nanotechnology for Cancer Immunotherapy, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China
b.
Hebei Key Laboratory of Crop Stress Biology, College of Agronomy and Biotechnology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China
c.
University of Edinburgh, Old College, South Bridge, Edinburgh EH89YL, Scotland, United Kingdom
d.
School of Basic Medical Sciences, Shenzhen University, Shenzhen 518060, China
e.
School of Materials Science and Engineering, Dongguan University of Technology, Dongguan 523808, China
f.
School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China
g.
The Second Affiliated Hospital of Guilin Medical College, Guilin 541199, China

zhangfan@bme.pumc.edu.cn

oumt@bme.pumc.edu.cn

meilin@bme.pumc.edu.cn

Received Date: 26 December 2023
Revised Date: 23 February 2024
Accepted Date: 25 February 2024
Available Online: 2 March 2024

Figures(4)

The utilization of fungicides in plants is very low, emphasizing the need to improve their utilization rates. In this study, the fungicide dimethachlon (Dim) was encapsulated within hollow mesoporous silica (HMSNs), and a coating was formed on the HMSNs surface through the reaction of Na₂CO₃ and CaCl₂, resulting in a pH-responsive delivery system named D/H@CaCO₃, proven valuable in preventing sclerotinia diseases in romaine lettuce. When disease-infested romaine lettuce was treated with D/H@CaCO₃, it degraded in the acidic microenvironment of Sclerotinia sclerotiorum (S. sclerotiorum), allowing for the pH-responsive release of Dim and effectively killing S. sclerotiorum. Moreover, the degraded CaCO₃ coating releases CO₂, which enhances the photosynthetic pigment contents, such as chlorophyll a, chlorophyll b, and carotenoids, in turn promoting plant growth. D/H@CaCO₃ is biologically safe for plants and is environmentally friendly, as confirmed by assessments involving zebrafish and earthworms. Given their antifungal capabilities, the controlled release of fungicides offers potential for plant protection.
- Nanopesticide,
- pH-responsive,
- Controlled release,
- Mesoporous silica nanoparticles,
- Sclerotinia sclerotiorum,
- Dimethachlon
1. [1]
  Y.H. Gao, Y.A. Xiao, K.K. Mao, et al., Chem. Eng. J. 383 (2020) 123169. doi: 10.1016/j.cej.2019.123169
2. [2]
  R. Bagchi, R.E. Gallery, S. Gripenberg, et al., Nature 506 (2014) 85–88. doi: 10.1038/nature12911
3. [3]
  W.J. Zhang, C.H. Hong, R.Y. Wang, et al. Int. J. Biol. Macromol. 219 (2022) 1112–1121. doi: 10.1016/j.ijbiomac.2022.08.168
4. [4]
  C.L. Xu, L.D. Cao, C. Cao, et al., Chem. Eng. J. 452 (2023) 139195. doi: 10.1016/j.cej.2022.139195
5. [5]
  A. Shelar, S.H. Nile, A.V. Singh, et al., Nano Micro Lett. 15 (2023) 153–189. doi: 10.1007/s40820-023-01099-1
6. [6]
  K. Wang, Y. Wang, Y.Y. Wu, et al., Chem. Eng. J. 474 (2023) 146012. doi: 10.1016/j.cej.2023.146012
7. [7]
  M.M. Hossain, F. Sultana, W.Q. Li, L.S.P. Tran, M.G. Mostofa, Cells 12 (2023) 1063. doi: 10.3390/cells12071063
8. [8]
  Z.A. Xie, W.L. Liang, Q.Y. Xiong, et al., Carbohydr. Polym. 291 (2022) 119576. doi: 10.1016/j.carbpol.2022.119576
9. [9]
  W. Wei, L.S. Xu, H. Peng, et al., Nat. Commun. 13 (2022) 2213. doi: 10.1038/s41467-022-29788-2
10. [10]
  C. Zhang, X.M. Wu, Y.Y. Wu, et al., J. Hazard. Mater. 403 (2021) 123888. doi: 10.1016/j.jhazmat.2020.123888
11. [11]
  L.H. Zheng, J.P. Wu, H. Hu, et al., J. Control. Release 361 (2023) 427–442. doi: 10.1016/j.jconrel.2023.07.037
12. [12]
  M. Dong, R. Tang, J. Li, et al., Chin. Chem. Lett. 35 (2024) 108539. doi: 10.1016/j.cclet.2023.108539
13. [13]
  J. Wang, H. Pan, J.Y. Li, et al., Chin. Chem. Lett. 34 (2023) 107828. doi: 10.1016/j.cclet.2022.107828
14. [14]
  C. Xu, H.E. Dobson, M.J. Yu, et al., J. Control. Release 357 (2023) 84–93. doi: 10.1016/j.jconrel.2023.03.036
15. [15]
  L.J. Ju, Z.X. Huang, Q. Shen, et al., Chin. Chem. Lett. 35 (2024) 109450. doi: 10.1016/j.cclet.2023.109450
16. [16]
  R. Tan, X.Y. Qiu, W.Y. Mu, et al., Chin. Chem. Lett. 35 (2024) 108343. doi: 10.1016/j.cclet.2023.108343
17. [17]
  W.C. Li, H.J. Zhou, X.Y. Zhang, et al., ACS Nano 17 (2023) 15199–15215. doi: 10.1021/acsnano.3c05120
18. [18]
  Y. Ding, Z.G. Xiao, F.R. Chen, et al., Sci. Total Environ. 863 (2023) 160900. doi: 10.1016/j.scitotenv.2022.160900
19. [19]
  Z.Q. Shi, Q.Q. Li, L. Mei, Chin. Chem. Lett. 31 (2020) 1345–1356. doi: 10.1016/j.cclet.2020.03.001
20. [20]
  Y.H. Gao, Y.H. Zhang, S. He, et al., Chem. Eng. J. 364 (2019) 361–369. doi: 10.1016/j.cej.2019.01.105
21. [21]
  C.L. Xu, Y.P. Shan, M. Bilal, et al., Chem. Eng. J. 395 (2020) 125093. doi: 10.1016/j.cej.2020.125093
22. [22]
  Y.H. Gao, Y. Liang, H.Q. Dong, et al., ACS Sustain. Chem. Eng. 8 (2020) 5716–5723. doi: 10.1021/acssuschemeng.0c00649
23. [23]
  P. Huang, D.Z. Lian, H.L. Ma, et al., Chin. Chem. Lett. 32 (2021) 3696–3704. doi: 10.1016/j.cclet.2021.06.034
24. [24]
  X.D. Yang, S.M. Ying, S. Zhang, et al., Chin. Chem. Lett. 35 (2024) 108674. doi: 10.1016/j.cclet.2023.108674
25. [25]
  S.J. Song, Y.L. Wang, J. Xie, et al., ACS Appl. Mater. Interfaces 11 (2019) 34258–34267. doi: 10.1021/acsami.9b12564
26. [26]
  L. Boufeldja, F. Boudard, K. Portet, et al., Int. J. Mol. Sci. 24 (2023) 12815. doi: 10.3390/ijms241612815
27. [27]
  L. Loladze, J.M. Nolan, L.H. Ziska, A.R. Knobbe, Mol. Nutr. Food Res. 63 (2019) 1801047. doi: 10.1002/mnfr.201801047
28. [28]
  J.Y. Tang, G. Tang, J.F. Niu, et al., J. Agric. Food Chem. 69 (2021) 2382–2391. doi: 10.1021/acs.jafc.0c06487
29. [29]
  Y.X. Gao, X. Zhang, X.N. Song, et al., Pest Manage. Sci. 80 (2024) 1981–1990. doi: 10.1002/ps.7930
30. [30]
  Q.Q. Li, Z.Q. Shi, M.T. Ou, et al., J. Control. Release 352 (2022) 450–458. doi: 10.1016/j.jconrel.2022.10.042
31. [31]
  R. Mohammadpour, D.L. Cheney, J.W. Grunberger, et al., J. Control. Release 324 (2020) 471–481. doi: 10.1016/j.jconrel.2020.05.027
32. [32]
  Y.X. Wang, L. Zhao, Y.B. Dai, et al., Adv. Mater. 35 (2023) 2307900. doi: 10.1002/adma.202307900
33. [33]
  Y.D. Deng, X.D. Zhang, X.S. Yang, et al., J. Hazard. Mater. 409 (2021) 124502. doi: 10.1016/j.jhazmat.2020.124502
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CaCO3-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release

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CaCO₃-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release