Citation: Chenghao Liu, Xiaofeng Lin, Jing Liao, Min Yang, Min Jiang, Yue Huang, Zhizhi Du, Lina Chen, Sanjun Fan, Qitong Huang. Carbon dots-based dopamine sensors: Recent advances and challenges[J]. Chinese Chemical Letters, ;2024, 35(12): 109598. doi: 10.1016/j.cclet.2024.109598 shu

Carbon dots-based dopamine sensors: Recent advances and challenges

Chenghao Liu ^a ,
Xiaofeng Lin ^{a, *,} ,
Jing Liao ^a ,
Min Yang ^a ,
Min Jiang ^a ,
Yue Huang ^a ,
Zhizhi Du ^a ,
Lina Chen ^a ,
Sanjun Fan ^{b, *,} ,
Qitong Huang ^{a, *,}

a.
Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Key Laboratory of Biomaterials and Biofabrication in Tissue Engineering of Jiangxi Province, Key Laboratory of Biomedical Sensors of Ganzhou, School of Medical and Information Engineering, School of Pharmacy, Scientific Research Center, Gannan Medical University, Ganzhou 341000, China
b.
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, United States

Linxf@gmu.edu.cn

fan.1113@osu.edu

hqt@gmu.edu.cn

Received Date: 9 December 2023
Revised Date: 26 January 2024
Accepted Date: 29 January 2024
Available Online: 4 February 2024

Figures(3)

Dopamine, a pivotal excitatory neurotransmitter, plays a crucial role in metabolic, cardiovascular, renal, central nervous, and endocrine systems. Abnormal dopamine within the human body can cause various diseases. Therefore, the precise quantification of dopamine levels, both in vivo and in vitro, holds paramount significance for clinical applications and physiological investigations. Carbon dots (CDs) exhibit a plethora of remarkable properties, including a substantial specific surface area, robust electrical conductivity, commendable biocompatibility, minimal toxicity, and high photostability. Considering these unique characteristics, CDs demonstrate substantial potential for fluorescent sensors, colorimetric sensors, and electrochemical sensors for dopamine detection. This review systematically examined the challenges and prospects for the utilization of CDs-based fluorescent sensors, electrochemical biosensors, and colorimetric sensors for monitoring dopamine levels in recent years. These findings unveil promising avenues for further advancements in the field of dopamine detection.
- Dopamine,
- Carbon dots,
- Fluorescent sensors,
- Colorimetric sensors,
- Electrochemical sensors
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