Citation: Sai Zhang, Gaochen Xu, Huan Yan, Qinghuan Wu, Jingjing Meng, Jindian Duan, Kai Guo. Electrooxidative [3 + 2] annulation of amidines with alkenes for the synthesis of spiroimidazolines[J]. Chinese Chemical Letters, ;2022, 33(12): 5128-5131. doi: 10.1016/j.cclet.2022.04.006 shu

Electrooxidative [3 + 2] annulation of amidines with alkenes for the synthesis of spiroimidazolines

College of Biotechnology and Pharmaceutical Engineering, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211816, China

duanjd@njtech.edu.cn

guok@njtech.edu.cn

Received Date: 16 January 2022
Revised Date: 2 April 2022
Accepted Date: 3 April 2022
Available Online: 8 April 2022

Figures(7)

The electrooxidative [3 + 2] annulation of amidines with 2-arylideneindane-1,3-diones or 4-alkylidene pyrazolones is reported using NaI as a redox catalyst and electrolyte under constant current electrolysis in an undivided cell. The current strategy features excellent functional group tolerance, simple operation, and mild conditions, thus providing an environmentally benign and efficient access to spiroimidazolines in moderate to good yields.
- Electrooxidative,
- Amidines,
- Alkenes,
- Spiroimidazolines,
- Annulation
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