Citation: Yuan Zhu, Yuanmei Hu, Juanmei Zeng, Chaoxiang Chen, Shunhua Li, Yunbao Jiang. Rapidly SO₂-responsive vesicles with intrinsic fluorescent indicators for membrane structure evolution[J]. Chinese Chemical Letters, ;2022, 33(12): 5180-5183. doi: 10.1016/j.cclet.2022.02.005 shu

Rapidly SO₂-responsive vesicles with intrinsic fluorescent indicators for membrane structure evolution

Yuan Zhu ^{a, b} ,
Yuanmei Hu ^{a, b} ,
Juanmei Zeng ^{a, b} ,
Chaoxiang Chen ^{a, b} ,
Shunhua Li ^{a, b, *,} ,
Yunbao Jiang ^{a, b}

a.
Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
b.
Xiamen Key Laboratory of Analytical Molecular Nanotechnology, Xiamen University, Xiamen 361005, China

lishua@xmu.edu.cn

Received Date: 26 September 2021
Revised Date: 9 January 2022
Accepted Date: 2 February 2022
Available Online: 6 February 2022

Figures(4)

Stimuli-responsive vesicles (SRVs) have been widely exploited as smart nanocarriers for biomedical applications. Herein, high-performance SO₂-responsive nanovesicles were reported to exemplify a new mode of SRVs. Structurally, the sensory vesicles were based on amphiphilic hydrogen-bonded (HB) polymers which can be facilely fabricated via modular self-assembly. The HB polymers are designed to consist of a melamine-barbituric acid HB skeleton with pendant anthracene fluorophores and amphiphilic side chains. Upon stimulation with increasing amount of SO₂, the vesicles in aqueous solution undergo an unusual morphology evolution including rapid fission into small ones, swelling and final collapse of the offspring vesicles. During this process, the intrinsic fluorescence response of the vesicles allows intuitive tracking of the hierarchical structural evolution of the self-assembled membranes and straightforward quantitation of the stimuli. This work exemplifies a rational design of auto-recording stimuli-responsive nanovesicles.
- Sulfur dioxide,
- Vesicles,
- Fluorescence,
- Self-assembly,
- Membrane probes
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通讯作者: 陈斌, bchen63@163.com

Rapidly SO₂-responsive vesicles with intrinsic fluorescent indicators for membrane structure evolution