Citation: Cheng-Xiao Zhao, Tian Liu, Manyi Xu, Hao Lin, Chong-Jing Zhang. A fundamental study on the fluorescence-quenching effect of nitro groups in tetraphenylethene AIE dyes with electron-withdrawing groups[J]. Chinese Chemical Letters, ;2021, 32(6): 1925-1928. doi: 10.1016/j.cclet.2021.02.008 shu

A fundamental study on the fluorescence-quenching effect of nitro groups in tetraphenylethene AIE dyes with electron-withdrawing groups

Cheng-Xiao Zhao ^{a, b, 1} ,
Tian Liu ^{a, 1} ,
Manyi Xu ^a ,
Hao Lin ^a ,
Chong-Jing Zhang ^{a, *,}

a.
State Key Laboratory of Bioactive Substance and Functions of Natural Medicines and Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China
b.
School of Pharmaceutical Science, Shanxi Medical University, Taiyuan 030001, China

zhangchongjing@imm.ac.cn

Received Date: 5 December 2020
Revised Date: 31 January 2021
Accepted Date: 2 February 2021
Available Online: 4 February 2021

Figures(7)

A nitro group is a common fluorescence quencher, but its quenching efficiency can be easily affected by the surrounding environment. To date, there has been no systematic study on the effects of electron-withdrawing groups on the quenching efficiency of nitro groups. Herein, by virtue of experimental validation and theoretical calculations, we found that strong electron-withdrawing groups, such as pyridinium and dicyanovinyl groups, are detrimental to the quenching effect of nitro groups. Decreasing the electron-withdrawing ability could restore the nitro group's quenching effect.
- Fluorescence,
- Aggregation-induced emission,
- Quenching effect,
- Nitro group
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