Citation: Renyi Pang, Ruichao Yao, Shiyao Lu, Yicheng Zhou, Wenbo Chen. Synthesis of S-monofluoromethyl phosphorothioates from P^V-H compounds and PhSO₂SCH₂F[J]. Chinese Chemical Letters, ;2021, 32(1): 453-456. doi: 10.1016/j.cclet.2020.05.032 shu

Synthesis of S-monofluoromethyl phosphorothioates from P^V-H compounds and PhSO₂SCH₂F

Renyi Pang ^a ,
Ruichao Yao ^a ,
Shiyao Lu ^a ,
Yicheng Zhou ^a ,
Wenbo Chen ^{a, b, *}

a.
Shanghai Key Laboratory of Materials Protection and Advanced Materials in Electric Power, Shanghai University of Electric Power, Shanghai 200090, China
b.
CAS Key Laboratory of Energy Regulation Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

wenbochen@shiep.edu.cn

Received Date: 14 March 2020
Revised Date: 7 May 2020
Accepted Date: 21 May 2020
Available Online: 27 May 2020

Figures(4)

S-Monofluoromethyl phosphorothioates represent an important class of organofluorine compounds and are reported here for the first time. A series of S-monofluoromethyl phosphorothioates are conveniently synthesized from different P^V-H compounds and PhSO₂SCH₂F under mild conditions. The method is compatible with common functional groups and provides potential opportunities to synthesize new bioactive molecules for medicinal chemistry.
- Fluorine,
- Monofluoromethylthio,
- Phosphorothioates,
- P^V-H compounds,
- PhSO₂SCH₂F
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Synthesis of S-monofluoromethyl phosphorothioates from PV-H compounds and PhSO2SCH2F

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通讯作者: 陈斌, bchen63@163.com

Synthesis of S-monofluoromethyl phosphorothioates from P^V-H compounds and PhSO₂SCH₂F