Citation: Han Jinliang, Yue Xiuxiu, Wang Jingpei, Zhang Yun, Wang Benhua, Song Xiangzhi. A ratiometric merocyanine-based fluorescent probe for detecting hydrazine in living cells and zebra fish[J]. Chinese Chemical Letters, ;2020, 31(6): 1508-1510. doi: 10.1016/j.cclet.2020.01.029 shu

A ratiometric merocyanine-based fluorescent probe for detecting hydrazine in living cells and zebra fish

Han Jinliang ^a ,
Yue Xiuxiu ^a ,
Wang Jingpei ^a ,
Zhang Yun ^a ,
Wang Benhua ^a,*, ,
Song Xiangzhi ^a,b,*,

a.
College of Chemistry & Chemical Engineering, Central South University, Changsha 410083, China
b.
Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha 410083, China

benhuawang@csu.edu.cn

song@rowland.harvard.edu

Received Date: 5 November 2019
Revised Date: 9 January 2020
Accepted Date: 10 January 2020
Available Online: 14 January 2020

Figures(5)

We developed a merocyanine-based fluorescent probe, NEPB, for tracing hydrazine (N₂H₄) in a ratiometric manner with large Stokes shifts and long emission wavelength. The fluorescence color of probe NEPB changed from green to yellow upon addition of hydrazine. Probe NEPB displayed high selectivity and sensitivity to hydrazine in solution, and could ratiometrically monitor N₂H₄ in living cells and zebrafish with low cytotoxicity.
- Fluorescent probe,
- Hydrazine,
- Merocyanine,
- Ratiometric,
- Cell imaging
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