Citation: Sheng Wanle, Lv Fan, Tang Bing, Hao Erhong, Jiao Lijuan. Toward the most versatile fluorophore: Direct functionalization of BODIPY dyes via regioselective C-H bond activation[J]. Chinese Chemical Letters, ;2019, 30(10): 1825-1833. doi: 10.1016/j.cclet.2019.08.004 shu

Toward the most versatile fluorophore: Direct functionalization of BODIPY dyes via regioselective C-H bond activation

Sheng Wanle ^a,b ,
Lv Fan ^a ,
Tang Bing ^a ,
Hao Erhong ^a,*, ,
Jiao Lijuan ^a,*,

a.
The Key Laboratory of Functional Molecular Solids, Ministry of Education, School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, China
b.
Department of Chemistry, Bengbu Medical College, Bengbu 233030, China

Author Bio:

Prof. Lijuan Jiao received her Bachelor’s degree (2000) from Shandong University, China, and obtained her Master’s degree (2003) under the supervision of Prof. Guanwu Wang at University of Science and Technology of China (USTC). She then moved to Louisiana State University, U. S. A., and obtained her Ph.D. (2007) under the supervision of Prof. Kevin M. Smith. She joined Anhui Normal University in 2008, and became a full professor (2010) at College of Chemistry and Materials Science. Her researchfocuses on the developmentof novel BODIPYand porphyrin related dyes, understanding their photophysical properties and studying their optoelectrical and biological applications. She received a SPP/JPP Young Investigator Award for her research in BODIPY chemistry in 2016

haoehong@ahnu.edu.cn

jiao421@ahnu.edu.cn

Received Date: 3 July 2019
Revised Date: 5 August 2019
Accepted Date: 5 August 2019
Available Online: 6 October 2019

Figures(31)

Fluorescent dyes are heavily sought for their potentials applications in bioimaging, sensing, theranostic, and optoelectronic materials. Among them, BODIPY dyes are privileged fluorophores that are now widely used in highly diverse research fields. The increasing success of BODIPY dyes is closely associated with their excellent and tunable photophysical properties due to their rich functionalization chemistry. Recently, growing research efforts have been devoted to the direct functionalization of the BODIPY core, because it allows the facile installation of desired functional groups in a single atom economical step. The challenges of this direct C-H derivation come from the difficulties in finding suitable functionalization agents and proper control of the regioselectivity of the functionalization. The aim of this work is to provide an overview of BODIPY dyes and a summarization of the different synthetic methodologies reported for direct C-H functionalization of the BODIPY framework.
- Dyes,
- Pigments,
- BODIPY,
- C-H activation,
- Radical substitution,
- Oxidative nucleophilic substitution
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