Citation: Li Li, Chen Yisha, Chen Weijie, Tan Ying, Chen Haiyan, Yin Jun. Photodynamic therapy based on organic small molecular fluorescent dyes[J]. Chinese Chemical Letters, ;2019, 30(10): 1689-1703. doi: 10.1016/j.cclet.2019.04.017 shu

Photodynamic therapy based on organic small molecular fluorescent dyes

Li Li ^a ,
Chen Yisha ^a ,
Chen Weijie ^b ,
Tan Ying ^c ,
Chen Haiyan ^a,**, ,
Yin Jun ^b,c,*,

a.
Department of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China
b.
Key Laboratory of Pesticide and Chemical Biology, Ministry of Education; Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis; International Joint Research Center for Intelligent BiosensingTechnology and Health; College of Chemistry, Central China Normal University, Wuhan 430079, China
c.
State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China

^**

1020092093@cpu.edu.cn

yinj@mail.ccnu.edu.cn

Received Date: 16 February 2019
Revised Date: 8 April 2019
Accepted Date: 8 April 2019
Available Online: 9 October 2019

Figures(9)

Photodynamic therapy (PDT) has shown promise as an effective treatment modality for cancer and other localized diseases due to its noninvasive properties and spatiotemporal selectivity. Near-infrared (NIR) fluorescent dyes based on organic small molecules are characterized with low cytotoxicity, good biocompatibility and excellent phototoxicity, which are widely used in PDT. In this review, we attempt to summarize the development of imaging-induced PDT based on organic small molecules and classify it according to the structures of dyes including cyanines, 4, 4-difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) analogues, phthalocyanine and other agents such as rhodamine analogues.
1. [1]
  K.R. Rong, Z.Y. Hou, J. Lin, et al., Small 13(2017) 1702299. doi: 10.1002/smll.201702299
2. [2]
  X. Li, Z. Liu, J. Yoon, et al., Angew. Chem. Int. Ed. 57(2018) 11522. doi: 10.1002/anie.201805138
3. [3]
  F. Bolze, S. Jenni, V. Heitz, et al., Chem. Commun. 53(2017) 12857-12877. doi: 10.1039/C7CC06133A
4. [4]
  J. Zhang, C.S. Jiang, H. Zhang, et al., Acta Pharmacol. Sin. B 8(2018) 137-146. doi: 10.1016/j.apsb.2017.09.003
5. [5]
  Z.Y. Sun, L.P. Zhang, F.P. Wu, et al., Adv. Funct. Mater. 27(2017) 1704079. doi: 10.1002/adfm.201704079
6. [6]
  X.S. Li, S.Y. Lee, J. Yoon, Chem. Soc. Rev. 47(2018) 1174-1188. doi: 10.1039/C7CS00594F
7. [7]
  B. Pucelik, R. Paczynski, G. Dubin, et al., PLoS One 12(2017) e0185984. doi: 10.1371/journal.pone.0185984
8. [8]
  A. Wiehe, H. SGtollberg, S. Runge, et al., J. Porphyrins Phthalocyanines 5(2001) 853-860. doi: 10.1002/jpp.553
9. [9]
  J. Matsumoto, K. Suzuki, M. Yasuda, et al., Bioorg. Med. Chem. 25(2017) 6536-6541. doi: 10.1016/j.bmc.2017.10.031
10. [10]
  Y.H. Chen, T.W. Wei, Z.J. Zhang, et al., Chin. Chem. Lett. 28(2017) 1957-1960. doi: 10.1016/j.cclet.2017.05.010
11. [11]
  X.X. Ma, L.L. Hu, X. Han, et al., Chin. Chem. Lett. 29(2018) 1489-1492. doi: 10.1016/j.cclet.2018.06.022
12. [12]
  C.J. Reinhardt, E.Y. Zhou, M.D. Jorgensen, et al., J. Am. Chem. Soc. 140(2018) 1011-1018. doi: 10.1021/jacs.7b10783
13. [13]
  W.J. Chen, Y.L. Pan, J.H. Chen, et al., Chin. Chem. Lett. 29(2018) 1435-1439.
14. [14]
  P.Z. Zhang, Z.Q. Guo, C.X. Yan, et al., Chin. Chem. Lett. 28(2017) 1952-1956. doi: 10.1016/j.cclet.2017.08.038
15. [15]
  Y. Zhao, M.M. Cerda, M.D. Pluth, Chem. Sci. 10(2019) 1873-1878. doi: 10.1039/C8SC05200J
16. [16]
  S.L. Leng, Q.L. Qiao, Y. Gao, et al., Chin. Chem. Lett. 28(2017) 1911-1915. doi: 10.1016/j.cclet.2017.03.034
17. [17]
  Y. Kang, J.L. Fan, Q. Jin, et al., Chin. Chem. Lett. 28(2017) 1991-1993. doi: 10.1016/j.cclet.2017.08.054
18. [18]
  Z.W. Yuan, L.J. Gui, H.Y. Chen, et al., ACS Appl. Mater. Interfaces 10(2018) 30994-31007. doi: 10.1021/acsami.8b09841
19. [19]
  J.R. Zheng, Y.Z. Shen, Z.Q. Xu, et al., Biosens. Bioelectron. 119(2018) 141-148. doi: 10.1016/j.bios.2018.08.014
20. [20]
  L.J. Gui, Z.W. Yuan, H.Y. Chen, et al., Chem. Commun. 54(2018) 9675-9678. doi: 10.1039/C8CC04246B
21. [21]
  Z.Q. Xu, X.T. Huang, X. Han, et al., Chemistry 7(2018) 1609-1628.
22. [22]
  D. Wu, L.Y. Chen, W. Lee, et al., Coord. Chem. Rev. 354(2018) 74-97. doi: 10.1016/j.ccr.2017.06.011
23. [23]
  X. Han, F. Hu, S.H. Liu, et al., Sens. Actuators B-Chem. 277(2018) 55-61. doi: 10.1016/j.snb.2018.08.109
24. [24]
  B. Ciubini, S. Visentin, L. Serpe, et al., Dyes Pigm. 160(2019) 806-813. doi: 10.1016/j.dyepig.2018.09.009
25. [25]
  L. Jiao, F.S. Long, J.N. Cui, et al., Chem. Commun. 54(2018) 9198-9201. doi: 10.1039/C8CC04582H
26. [26]
  J. Atchison, S. Kamila, H. Nesbitt, et al., Chem. Commun. 53(2017) 2009-2012. doi: 10.1039/C6CC09624G
27. [27]
  C. Shirata, J. Kaneko, Y. Inagaki, et al., Sci. Rep. 7(2017) 13958. doi: 10.1038/s41598-017-14401-0
28. [28]
  J. Chen, X. Tan, S.L. Luo, et al., J. Innov. Opt. Health Sci. 11(2018) 1850016. doi: 10.1142/S1793545818500165
29. [29]
  S.L. Luo, X. Tan, S.T. Fang, et al., Adv. Funct. Mater. 26(2016) 2826-2835. doi: 10.1002/adfm.201600159
30. [30]
  X.Q. Meng, J.L. Zhang, Z.H. Sun, et al., Theranostics 8(2018) 6025-6034. doi: 10.7150/thno.26607
31. [31]
  X.Q. Meng, Y.T. Yang, L.H. Zhou, et al., Theranostics 7(2017) 1781-1794. doi: 10.7150/thno.18437
32. [32]
  A. Turksoy, D. Yildiz, E.U. Akkaya, Coord. Chem. Rev. 379(2019) 47-64. doi: 10.1016/j.ccr.2017.09.029
33. [33]
  C.J. Reinhardt, E.Y. Zhou, M.D. Jorgensen, et al., J. Am. Chem. Soc. 140(2018) 1011-1018. doi: 10.1021/jacs.7b10783
34. [34]
  J.A. Peterson, C. Wijesooriya, E.J. Gehrmann, et al., J. Am. Chem. Soc. 140(2018) 7343-7346. doi: 10.1021/jacs.8b04040
35. [35]
  B.S. Kim, B.L. Sui, X.L. Yue, et al., Eur. J. Org. Chem. 2017(2017) 25-28. doi: 10.1002/ejoc.201601054
36. [36]
  M.L. Li, R.S. Tian, J.L. Fan, et al., Dyes Pigm. 147(2017) 99-105. doi: 10.1016/j.dyepig.2017.07.048
37. [37]
  F.F. Xue, P. Wei, X.T. Ge, et al., Dyes Pigm. 156(2018) 285-290. doi: 10.1016/j.dyepig.2018.04.008
38. [38]
  H.S. Jung, J.Y. Han, H. Shi, et al., J. Am. Chem. Soc. 139(2017) 7595-7602. doi: 10.1021/jacs.7b02396
39. [39]
  C.S. Kue, A. Kamkaew, H.B. Lee, et al., Mol. Pharm. 12(2015) 212-222. doi: 10.1021/mp5005564
40. [40]
  M. Li, S. Long, Y. Kang, et al., J. Am. Chem. Soc. 140(2018) 15820-15826. doi: 10.1021/jacs.8b09117
41. [41]
  R.L. Watley, S.G. Awuah, M. Bio, et al., Chem.-Asian J. 10(2015) 1335-1343. doi: 10.1002/asia.201500140
42. [42]
  N. Shivran, M. Tyagi, S. Mula, et al., Eur. J. Med. Chem. 122(2016) 352-365. doi: 10.1016/j.ejmech.2016.06.050
43. [43]
  R. Ridhi, G.S.S. Saini, S.K. Tripathi, Sens. Actuators B-Chem. 255(2018) 1849-1868. doi: 10.1016/j.snb.2017.08.213
44. [44]
  G. Avsar, F.A. Sari, A.G. Yuzer, et al., Int. J. Pharm. 505(2016) 369-375. doi: 10.1016/j.ijpharm.2016.04.023
45. [45]
  F.Y. Lambrecht, K. Ocakoglu, O. Er, et al., J. Label Compd. Radiopharm. 59(2016) 221-227. doi: 10.1002/jlcr.3395
46. [46]
  Z.X. Zhao, P.S. Chan, H.G. Li, et al., Inorg. Chem. 51(2012) 812-821. doi: 10.1021/ic201178e
47. [47]
  K. Li, L. Qiu, Q.Z. Liu, et al., J. Photochem. Photobiol. B 174(2017) 243-250. doi: 10.1016/j.jphotobiol.2017.08.003
48. [48]
  A.D. Gülmez, M. Göksel, M. Durmus, et al., J. Porphyrins Phthalocyanines 21(2017) 1-8. doi: 10.1142/S1088424616501273
49. [49]
  B.Y. Zheng, X.Q. Yang, Y. Zhao, et al., Eur. J. Med. Chem. 155(2018) 24-33. doi: 10.1016/j.ejmech.2018.05.039
50. [50]
  J.J. Wu, Z. Ye, F. Meng, et al., Talanta 181(2018) 239-247. doi: 10.1016/j.talanta.2018.01.028
51. [51]
  D.Y. Lee, K.M.K. Swamy, J.H. Hong, et al., Sens. Actuators B-Chem. 266(2018) 416-421. doi: 10.1016/j.snb.2018.03.133
52. [52]
  S.L. Shen, X.F. Zhang, Y.Q. Ge, et al., Sens. Actuators B-Chem. 256(2018) 261-267. doi: 10.1016/j.snb.2017.10.103
53. [53]
  W.Piao, K.J.Hanaoka, T.Fujisawa, etal., J.Am.Chem.Soc.139(2017)13713-13719. doi: 10.1021/jacs.7b05019
54. [54]
  M. Chiba, Y. Ichikawa, M. Kamayi, et al., Angew. Chem. Int. Ed. 56(2017) 10418-10422. doi: 10.1002/anie.201704793
55. [55]
  Y.S. Chou, C.C. Chang, T.C. Chang, et al., Biomed Res. Int. 2013(2012) 930281.
56. [56]
  J. Mei, Y.H. Huang, H. Tian, ACS Appl. Mater. Interfaces 10(2018) 12217-12261. doi: 10.1021/acsami.7b14343
57. [57]
  X.G. Gu, X.Y. Zhan, H.L. Ma, et al., Adv. Mater. 30(2018) 1801065. doi: 10.1002/adma.201801065
58. [58]
  D.D. La, S.V. Bhosale, L.A. Jones, et al., ACS Appl. Mater. Interfaces 10(2018) 12189-12216. doi: 10.1021/acsami.7b12320
59. [59]
  C.J. Zhang, Q.L. Hu, G.X. Feng, et al., Chem. Sci. 6(2015) 4580-4586. doi: 10.1039/C5SC00826C
60. [60]
  Y.Y. Yuan, C.J. Zhang, S.D. Xu, et al., Chem. Sci. 7(2016) 1862-1866. doi: 10.1039/C5SC03583J
61. [61]
  D. Wang, H.F. Su, R.T.K. Kwok, et al., Chem. Sci. 9(2018) 3685-3693. doi: 10.1039/C7SC04963C
62. [62]
  J.L. Zou, H.G. Lu, X.W. Zhao, et al., Dyes Pigm. 151(2018) 45-53. doi: 10.1016/j.dyepig.2017.12.044
63. [63]
  Y. Li, K.N. Wang, B. Liu, et al., Sens. Actuators B-Chem. 255(2018) 193-202. doi: 10.1016/j.snb.2017.08.041
64. [64]
  Y.L. Lv, M. Liu, Y. Zhang, et al., ACS Nano 12(2018) 1350-1358. doi: 10.1021/acsnano.7b07716
65. [65]
  J. Qi, C.W. Sun, H.Q. Zhang, et al., ACS Nano 12(2018) 7936-7945. doi: 10.1021/acsnano.8b02452
66. [66]
  H.D. Li, X. Zhou, J.L. Fan, et al., Sens. Actuators B-Chem. 254(2018) 709-718. doi: 10.1016/j.snb.2017.07.082
67. [67]
  W.B. Hu, M. Xie, H. Zhao, et al., Chem. Sci. 9(2018) 999-1005. doi: 10.1039/C7SC04044J
68. [68]
  Z. Zheng, T.F. Zhang, H.X. Liu, et al., ACS Nano 12(2018) 8145-8159. doi: 10.1021/acsnano.8b03138
69. [69]
  Y. Liu, X.X. Hu, L.L. Wang, et al., Dyes Pigm. 145(2017) 168-173. doi: 10.1016/j.dyepig.2017.06.003
70. [70]
  M. Li, J. Xia, R.S. Tian, et al., J. Am. Chem. Soc. 140(2018) 14851-14859. doi: 10.1021/jacs.8b08658
71. [71]
  X.Y. Yang, D.Y. Wang, Y.H. Shi, et al., ACS Appl. Mater. Interfaces 10(2018) 12431-12440. doi: 10.1021/acsami.8b00276
72. [72]
  Z. Lv, L. Zou, H.J. Wei, et al., ACS Appl. Mater. Interfaces 10(2018) 19523-19533. doi: 10.1021/acsami.8b05944
73. [73]
  W.J. Hou, Y. Liu, Y. Jiang, et al., Nanoscale 10(2018) 10986-10990. doi: 10.1039/C8NR01096J
74. [74]
  L.L. Rui, H.L. Cao, Y.D. Xue, et al., Chin. Chem. Lett. 27(2016) 1412-1420. doi: 10.1016/j.cclet.2016.07.011
75. [75]
  Y. Zhu, W.H. Lin, W. Zhang, et al., Chin. Chem. Lett. 28(2017) 1875-1877. doi: 10.1016/j.cclet.2017.06.017
76. [76]
  J. Mou, T.Q. Lin, F.Q. Huang, et al., Biomaterials 84(2016) 13-24. doi: 10.1016/j.biomaterials.2016.01.009
77. [77]
  Z.Q. Xu, J.H. Chen, L.L. Hu, et al., Chin. Chem. Lett. 28(2017) 1935-1942. doi: 10.1016/j.cclet.2017.07.018
78. [78]
  C.B. Huang, L. Xu, J.L. Zhu, et al., J. Am. Chem. Soc. 139(2017) 9459-9462. doi: 10.1021/jacs.7b04659
79. [79]
  J.C. Xu, H.Q. Yuan, L.T. Zeng, et al., Chin. Chem. Lett. 29(2018) 1456-1464. doi: 10.1016/j.cclet.2018.08.012
80. [80]
  H.J. Lee, Y.G. Lee, J. Kang, et al., Chem. Sci. 10(2019) 1000-1007. doi: 10.1039/C8SC04943B
81. [81]
  J.L. Zhu, P.P. Jia, N. Li, et al., Chin. Chem. Lett. 29(2018) 1445-1450. doi: 10.1016/j.cclet.2018.09.002
82. [82]
  D.F. Yue, M.L. Wang, F. Deng, et al., Chin. Chem. Lett. 29(2018) 648-656. doi: 10.1016/j.cclet.2018.01.046
83. [83]
  W.J. Qin, C.C. Xu, Y.F. Zhao, et al., Chin. Chem. Lett. 29(2018) 1451-1455. doi: 10.1016/j.cclet.2018.04.007
84. [84]
  H.L. Un, S. Wu, C.B. Huang, et al., Chem. Commun. 51(2015) 3143-3146. doi: 10.1039/C4CC09488C
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