Citation: Wang Xin-Rui, Cheng Hui-Min, Gao Xue-Wei, Zhou Wei, Li Shu-Jing, Cao Xue-Li, Yan Dongpeng. Intercalation assembly of kojic acid into Zn-Ti layered double hydroxide with antibacterial and whitening performances[J]. Chinese Chemical Letters, ;2019, 30(4): 919-923. doi: 10.1016/j.cclet.2019.03.050 shu

Intercalation assembly of kojic acid into Zn-Ti layered double hydroxide with antibacterial and whitening performances

a.
Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 100048, China
b.
Department of Chemistry, Beijing Normal University, Beijing 100875, China

caoxli@th.btbu.edu.cn

yandp@bnu.edu.cn

Received Date: 8 March 2019
Revised Date: 20 March 2019
Accepted Date: 23 March 2019
Available Online: 28 April 2019

Figures(8)

A melanin synthesis inhibitor and bacteriostatic agent, kojic acid (KA) has been intercalated into Zn-Ti layered double hydroxide (LDH) by an anion-exchange reaction. The structure and the thermal stability of the samples were characterized by XRD, FT-IR, TG-DTA and SEM. The study of KA release from ZnTi-KA-LDH in phosphate buffered solution (pH 5) implies that ZnTi-KA-LDH is a better controlled release system than pure KA. Meanwhile, the mechanisms of slow release were assessed by using four commonly kinetic models. The antimicrobial activity of ZnTi-KA-LDH was tested against three kinds of bacteria. The inhibition of L-dopa oxidation was tested to verify its skin whitening effect. The studies suggest that the kojic acid intercalated LDHs has the potential application as a safely functional composite in cosmetic.
- Layered double hydroxide,
- Kojic acid,
- Intercalation,
- Slow release,
- Antimicrobial,
- Tyrosinase
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