Citation: Zhou Hui, Xiao Yuling, Hong Xuechuan. New NIR-Ⅱ dyes without a benzobisthiadiazole core[J]. Chinese Chemical Letters, ;2018, 29(10): 1425-1428. doi: 10.1016/j.cclet.2018.08.009 shu

New NIR-Ⅱ dyes without a benzobisthiadiazole core

a.
State Key Laboratory of Virology, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery(MOE) and Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China
b.
Medical College, Tibet University, Lasa 850000, China

Corresponding author: Hong Xuechuan, xhy78@whu.edu.cn
Received Date: 20 July 2018
Revised Date: 20 August 2018
Accepted Date: 22 August 2018
Available Online: 27 October 2018

Figures(5)

Fluorescent NIR-Ⅱ imaging has a wide range of benefits not offered by other imaging modalities for biomedical applications, derived from its combination of high spatial and temporal resolution due to reduced photon absorption, scattering and tissue auto-fluorescence. Compared to the well-studied NIR-Ⅰ small-molecule fluorophores, the structures of NIR-Ⅱ fluorophores are scarce. To date, the main fluorophore units are composed of conjugated π system with a benzobisthiadiazole (BBTD) core and donor-acceptor-donor (D-A-D) structure. Herein, researchers Yang et al. and Zhang et al. have reported new NIR-Ⅱ probes ECX and FD-1080 respectively without a BBTD core which are highlighted.
- NIR-Ⅱ dyes,
- Fluorescence imaging,
- D-A-D structure,
- 1064 nm excitation,
- In vivo imaging
1. [1]
  J.R. Hou, D. Jin, B. Chen, et al., Chin. Chem. Lett. 28(2017) 1681-1687. doi: 10.1016/j.cclet.2017.03.037
2. [2]
  F.L. Song, R. Liang, J.D. Deng, et al., Chin. Chem. Lett. 28(2017) 1997-2000. doi: 10.1016/j.cclet.2017.08.023
3. [3]
  G.S. Hong, A.L. Antaris, H.J. Dai, Nat. Biomed. Eng. 1(2017) 0010.
4. [4]
  A.L. Antaris, H. Chen, K. Cheng, et al., Nat. Mater. 15(2016) 235-242. doi: 10.1038/nmat4476
5. [5]
  J. Yang, Q. Xie, H. Zhou, et al., J. Proteome Res. 17(2018) 2428-2439. doi: 10.1021/acs.jproteome.8b00181
6. [6]
  A.L. Antaris, H. Chen, S. Diao, et al., Nat. Commun. 8(2017) 15269. doi: 10.1038/ncomms15269
7. [7]
  Y. Sun, C.R. Qu, H. Chen, et al., Chem. Sci. 7(2016) 6203-6207. doi: 10.1039/C6SC01561A
8. [8]
  Y. Sun, M.M. Ding, X.D. Zeng, et al., Chem. Sci. 8(2017) 3489-3493. doi: 10.1039/C7SC00251C
9. [9]
  Y. Sun, X.D. Zeng, Y.L. Xiao, et al., Chem. Sci. 9(2018) 2092-2097. doi: 10.1039/C7SC04774F
10. [10]
  Y. Xu, M. Tian, H. Zhang, et al., Chin. Chem. Lett. 29(2018) 1093-1097. doi: 10.1016/j.cclet.2018.03.032
11. [11]
  X.D. Zeng, Y.L. Xiao, J.C. Lin, et al., Adv. Healthcare Mater. 7(2018) 1800589. doi: 10.1002/adhm.v7.18
12. [12]
  D. Wu, Y.Z. Shen, J.H. Chen, et al., Chin. Chem. Lett. 28(2017) 1979-1982. doi: 10.1016/j.cclet.2017.07.004
13. [13]
  X. Li, R. Zhao, Y. Yang, et al., Chin. Chem. Lett. 28(2017) 1258-1261. doi: 10.1016/j.cclet.2016.12.029
14. [14]
  J. Wen, P. Xia, Z. Zheng, et al., Chin. Chem. Lett. 28(2017) 2005-2008. doi: 10.1016/j.cclet.2017.09.014
15. [15]
  M. Hong, A. Liu, Y. Xu, et al., Chin. Chem. Lett. 27(2016) 989-992. doi: 10.1016/j.cclet.2016.03.027
16. [16]
  Z.H. Lei, X.R. Li, X. Luo, et al., Angew. Chem. Int. Ed. 56(2017) 2979-2983. doi: 10.1002/anie.201612301
17. [17]
  B.H. Li, L.F. Lu, M.Y. Zhao, et al., Angew. Chem. Int. Ed. 57(2018) 7483-7487. doi: 10.1002/anie.201801226
1. [1]
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2. [2]
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3. [3]
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4. [4]
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13. [13]
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15. [15]
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沈阳化工大学材料科学与工程学院沈阳 110142