Citation: Xiong Wei, Zhou Hantao, Zhang Chong, Lu Hua. An amino acid-based gelator for injectable and multi-responsive hydrogel[J]. Chinese Chemical Letters, ;2017, 28(11): 2125-2128. doi: 10.1016/j.cclet.2017.09.019 shu

An amino acid-based gelator for injectable and multi-responsive hydrogel

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

Corresponding author: Lu Hua, chemhualu@pku.edu.cn
Received Date: 24 June 2017
Revised Date: 5 September 2017
Accepted Date: 5 September 2017
Available Online: 6 November 2017

Figures(5)

Hydrogels formed by gelators have attracted growing attention for their promising application in biomaterials and biotechnology. We describe in this paper the generation and characterization of a novel photo-, thermal-and pH-responsive hydrogel based on an amino acid gelator AA-Azo-EG₆. Specifically, the gelator bears an amino acid head, an azobenzene (Azo) linker, and a short oligoethylene glycol tail (EG₆). The resulting AA-Azo-EG₆ hydrogel is injectable and exhibits interesting helical self-assembled structures. Meanwhile, the hydrogel is able to experience a gel-sol or gel-precipitate phase transition responding to external stimuli. Thus, this AA-Azo-EG₆ gelator is a promising building block for intelligent materials and drug delivery.
- Multi-responsive,
- Injectable,
- Amino acid,
- Gelator,
- Hydrogel
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