Citation: Basha Mai A., Abd El-Rahman Mohamed K., Bebawy Lories I., Salem Maissa Y.. Novel potentiometric application for the determination of amprolium HCl in its single and combined dosage form and in chicken liver[J]. Chinese Chemical Letters, ;2017, 28(3): 612-618. doi: 10.1016/j.cclet.2016.11.012 shu

Novel potentiometric application for the determination of amprolium HCl in its single and combined dosage form and in chicken liver

a.
National Organization of Drug Control and Research (NODCAR), Cairo 29, Egypt
b.
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt

Corresponding author: Basha Mai A., mamo1134@yahoo.com
Received Date: 27 July 2016
Revised Date: 19 October 2016
Accepted Date: 4 November 2016
Available Online: 19 March 2016

Figures(7)

Three novel amprolium HCl (AMP)-selective electrodes were investigated with 2-nitrophenyl octylether as a plasticiser in a polymeric matrix of polyvinyl chloride (PVC). Sensor Ⅰ was fabricated using potassium tetrakis (4-chlorophenyl) borate (TpClPB) as a cationic exchanger without incorporation of an ionophore. Sensor Ⅱ used 2-hydroxy propyl β-cyclodextrin as an ionophore while sensor Ⅲ used p-tert-butylcalix[8] arene as an ionophore. The three proposed sensors showed Nernestian response slopes of 29.2±0.8, 29.3±0.6 and 30.2±0.4 mV/decade over the concentration range from 10-6 to 10-2 mol L^-1, respectively. The proposed sensors displayed useful analytical characteristics for the determination of AMP in bulk powder, different pharmaceutical formulations, and chicken liver and in the presence of ethopabate. The proposed method was validated according to ICH guidelines for its linearity, accuracy, precision and robustness.
- Amprolium HCl,
- Cationic exchanger,
- Ionophore,
- Ion selective electrodes,
- Ethopabate,
- Chicken liver
1. [1]
  M.J. O'Neil, The Merck Index:An Encyclopedia of Chemicals, Drugs, and Biologicals, 14th ed., White House Station, NJ, USA, 2006.
2. [2]
  A. El Nagar, A. Ibrahim, Case study of the Egyptian poultry sector, (2016). http://www.fao.org/events/docs.part1.
3. [3]
  Veterinary Drug MRL Database, (2013) http://www.mrldatabase.com/results.cfm (Accessed 14.08.13).
4. [4]
  British Pharmacopoeia Commission, British Pharmacopoeia (Volume Veterinary), Stationary Office, London, 2013.
5. [5]
  Salama N.N., Fouad M.M., Rashed N.S.. Validated chromatographic methods for simultaneous determination of Amprolium hydrochloride and Ethopabate in veterinary preparation[J]. Int. J. Pharm. Biomed. Res., 2012,3:185-190.
6. [6]
  Martínez-Villalba A., Moyano E., Galceran M.T.. Analysis of amprolium by hydrophilic interaction liquid chromatography-tandem mass spectrometry[J]. J. Chromatogr. A, 2010,1217:5802-5807. doi: 10.1016/j.chroma.2010.07.041
7. [7]
  Hussein L.A., Magdy N., Abbas M.M.. Five different spectrophotometric methods for determination of Amprolium hydrochloride and Ethopabate binary mixture[J]. Spectrochim. Acta A, 2015,138:395-405. doi: 10.1016/j.saa.2014.11.073
8. [8]
  El-Hawary W.F.. Determination of lignocaine and amprolium in pharmaceutical formulations using AAS[J]. J. Pharm. Biomed. Anal., 2002,27:97-105. doi: 10.1016/S0731-7085(01)00514-3
9. [9]
  Issa Y.M., Rizk M.S., Shoukry A.F., Atia E.M.. Plastic membrane electrodes for amprolium[J]. Microchim. Acta, 1998,129:195-200. doi: 10.1007/BF01244741
10. [10]
  Tan H.S.I., Ramachandran P., Cacini W.. High performance liquid chromatographic assay of amprolium and ethopabate in chicken feed using solid-phase extraction[J]. J. Pharm. Biomed. Anal., 1996,15:259-265. doi: 10.1016/0731-7085(96)01829-8
11. [11]
  Hamamoto K., Koike R., Shirakura A., Sasaki A., Machida Y.. Rapid and sensitive determination of amprolium in chicken plasma by high-performance liquid chromatography with post-column reaction[J]. J. Chromatogr. B, 1997,693:489-492. doi: 10.1016/S0378-4347(97)00088-1
12. [12]
  Hormazabal V., Yndestad M.. Rapid assay for the determination of residues of amprolium and ethopabate in chicken meat by HPLC[J]. J. Liq. Chromatogr. Relat. Technol., 1996,19:2517-2525. doi: 10.1080/10826079608014034
13. [13]
  El-Kosasy A.M., Hussein L.A., Magdy N., Abbas M.M.. Sensitive spectrofluorimetric methods for determination of ethopabate and amprolium hydrochloride in chicken plasma and their residues in food samples[J]. Spectrochim. Acta A, 2015,150:430-439. doi: 10.1016/j.saa.2015.05.082
14. [14]
  Moloney M., Clarke L., O'Mahony J.. Determination of 20 coccidiostats in egg and avian muscle tissue using ultra high performance liquid chromatography-tandem mass spectrometry[J]. J. Chromatogr. A, 2012,1253:94-104. doi: 10.1016/j.chroma.2012.07.001
15. [15]
  Chiaochan C., Koesukwiwat U., Yudthavorasit S., Leepipatpiboon N.. Efficient hydrophilic interaction liquid chromatography-tandem mass spectrometry for the multiclass analysis of veterinary drugs in chicken muscle[J]. Anal. Chim. Acta, 2010,682:117-129. doi: 10.1016/j.aca.2010.09.048
16. [16]
  Squadrone S., Mauro C., Ferro G.L., Amato G., Abet M.C.. Determination of amprolium in feed by a liquid chromatography-mass spectrometry method[J]. J. Pharm. Biomed. Anal., 2008,48:1457-1461. doi: 10.1016/j.jpba.2008.09.024
17. [17]
  Song W.L., Huang M., Rumbeiha W., Li H.. Determination of amprolium carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry[J]. Rapid Commun. Mass Spectrom., 2007,21:1944-1950. doi: 10.1002/(ISSN)1097-0231
18. [18]
  Hormazábal V., Yndestad M., Ostensvik O.. Determination of amprolium ethopabate, lasalocid, monensin, narasin, and salinomycin in feed by liquid chromatography-mass spectrometry[J]. J. Liq. Chromtogr. Relat. Technol., 2002,25:2655-2663. doi: 10.1081/JLC-120014382
19. [19]
  Hormazábal V., Yndestad M.. Determination of amprolium ethopabate, lasalocid, monensin, narasin, and salinomycin in chicken tissues, plasma, and egg using liquid chromatography-mass spectrometry[J]. J. Liq. Chromtogr. Relat. Technol., 2000,23:1585-1598. doi: 10.1081/JLC-100100437
20. [20]
  Fink D.W., deFontenay G., Bonnefille P., Camarade M., Monier C.. Further studies on the spectrophotometric determination of amprolium[J]. J. AOAC Int., 2004,87:677-680.
21. [21]
  Martínez-Villalba A., Núñez O., Moyano E., Galceran M.T.. Field amplified sample injection-capillary zone electrophoresis for the analysis of amprolium in eggs[J]. Electrophoresis, 2013,34:870-876. doi: 10.1002/elps.201200579
22. [22]
  Gupta V.K., Jain R., Radhapyari K., Jadon N., Agarwal S.. Voltammetric techniques for the assay of pharmaceuticals-a review[J]. Anal. Biochem., 2011,408:179-196. doi: 10.1016/j.ab.2010.09.027
23. [23]
  El-Rahman M.K.A., Zaazaa H.E., Badr ElDin N., Moustafa A.A.. Novel strategy for online monitoring of the degradation kinetics of propantheline bromide via a calixarene-based ion-selective electrode[J]. Talanta, 2015,132:52-58. doi: 10.1016/j.talanta.2014.08.068
24. [24]
  El-Rahman M.K.A., Salem M.Y.. Ion selective electrode (in-line analyzer) versus UV-spectroscopy (at-line analyzer); which strategy offers more opportunities for real time monitoring of the degradation kinetics of pyridostigmine bromide[J]. Sens. Actuators B, 2015,220:255-262. doi: 10.1016/j.snb.2015.05.092
25. [25]
  El-Rahman M.K.A., Rezk M.R., Mahmoud A.M., Elghobashy M.R.. Design of a stable solid-contact ion-selective electrode based on polyaniline nanoparticles as ion-to-electron transducer for application in process analytical technology as a real-time analyzer[J]. Sens. Actuators. B, 2015,208:14-21. doi: 10.1016/j.snb.2014.11.009
26. [26]
  Mahmoud A.M., El-Rahman M.K.A., Elghobashy M.R., Rezk M.R.. Carbon nanotubes versus polyaniline nanoparticles; which transducer offers more opportunities for designing a stable solid contact ion-selective electrode[J]. J. Electroanal. Chem., 2015,755:122-126. doi: 10.1016/j.jelechem.2015.07.045
27. [27]
  Mittal S.K., Kumar A., Gupta N., Kaur S., Kumar S.. 8-Hydroxyquinoline based neutral tripodal ionophore as a copper (Ⅱ) selective electrode and the effect of remote substitutents on electrode properties[J]. Anal. Chim. Acta, 2007,585:161-170. doi: 10.1016/j.aca.2006.12.011
28. [28]
  Zanganeh A.R., Amini M.K.. Polypyrrole-modified electrodes with induced recognition sites for potentiometric and voltammetric detection of copper (Ⅱ) ion[J]. Sens. Actuators B, 2008,135:358-365. doi: 10.1016/j.snb.2008.09.005
29. [29]
  Górski L., Matusevich A., Parzuchowski P., Łuciuk I., Malinowska E.. Fluorideselective polymeric membrane electrodes based on Zr (Ⅳ)-and Al (Ⅲ)-salen ionophores of various structures[J]. Anal. Chim. Acta, 2010,665:39-46. doi: 10.1016/j.aca.2010.03.021
30. [30]
  Sideris E.E., Valsami G.N., Koupparis M.A., Macheras P.E.. Studies on the interaction of diflunisal ion with cyclodextrins using ion-selective electrode potentiometry[J]. Eur. J. Pharm. Sci., 1999,7:271-278. doi: 10.1016/S0928-0987(98)00035-9
31. [31]
  Flink S., van Veggel F.C.J.M., Reinhoudt D.N.. Sensor functionalities in selfassembled monolayers[J]. Adv. Mater., 2000,12:1315-1328. doi: 10.1002/(ISSN)1521-4095
32. [32]
  E. Bakker, Y. Qin, Electrochemical sensors, Anal. Chem. 78(2006) 3965-3984.
33. [33]
  El-Kosasy A.M., Nebsen M., El-Rahman M.K.A., Salem M.Y., El-Bardicy M.G.. Comparative study of 2-hydroxy propyl beta cyclodextrin and calixarene as ionophores in potentiometric ion-selective electrodes for neostigmine bromide[J]. Talanta, 2011,85:913-918. doi: 10.1016/j.talanta.2011.04.071
34. [34]
  Zareh M.M., Malinowska E.. Phosphorated calix6arene derivatives as an ionophore for atropine-selective membrane electrodes[J]. J. AOAC Int., 2007,90:147-152.
35. [35]
  Antoniadou-Vyza E., Buckton G., Michaleas S.G., Loukas Y.L., Efentakis M.. The formation of an inclusion complex of methocarbamol with hydroxypropyl-β-cyclodextrin:the effect on chemical stability, solubility and dissolution rate[J]. Int. J. Pharm., 1997,158:233-239. doi: 10.1016/S0378-5173(97)00258-5
36. [36]
  Lindner E., Umezawa Y.. Performance evaluation criteria for preparation and measurement of macro-and microfabricated ion-selective electrodes (IUPAC technical report)[J]. Pure Appl. Chem., 2008,80:85-104.
37. [37]
  Kaliappan R., Ling Y.H., Kaifer A.E., Ramamurthy V.. Sulfonatocalix[8] arene as a potential reaction cavity:photo-and electro-active dicationic guests arrest conformational equilibrium[J]. Langmuir, 2009,25:8982-8992. doi: 10.1021/la900659r
38. [38]
  International Conference on Harmonization (ICH), Q2B:Validation of Analytical Procedures:Methodology, The European Agency for the Evaluation of Medicinal Products, Geneva, Switzerland, 1996.
39. [39]
  Bakker E., Pretsch E.. Potentiometric sensors for trace-level analysis[J]. Trends Anal. Chem., 2005,24:199-207. doi: 10.1016/j.trac.2005.01.003
40. [40]
  Baumann E.W.. Trace fluoride determination with specific ion electrode[J]. Anal. Chim. Acta, 1968,42:127-132. doi: 10.1016/S0003-2670(01)80277-4
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