Citation: Tao Li, Bin Wang, Nicole J. de Voogd, Xu-Li Tang, Qi Wang, Mei-Jun Chu, Ping-Lin Li, Guo-Qiang Li. Two new diterpene alkaloids from the South China Sea Sponge Agelas aff. Nemoechinata[J]. Chinese Chemical Letters, ;2016, 27(7): 1048-1051. doi: 10.1016/j.cclet.2016.05.017 shu

Two new diterpene alkaloids from the South China Sea Sponge Agelas aff. Nemoechinata

Tao Li ^a ,
Bin Wang ^b ,
Nicole J. de Voogd ^c ,
Xu-Li Tang ^d ,
Qi Wang ^d ,
Mei-Jun Chu ^d ,
Ping-Lin Li ^d,, ,
Guo-Qiang Li ^d,,

a.
Marine Science and Technology College, Zhejiang Ocean University, Zhoushan 316022, China
b.
School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China
c.
National Museum of Natural History, 2300 RA Leiden, Netherlands
d.
College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, China
e.
School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China

Corresponding author: Ping-Lin Li, lipinglin@ouc.edu.cn Guo-Qiang Li, liguoqiang@ouc.edu.cn
Received Date: 28 March 2016
Revised Date: 7 May 2016
Accepted Date: 12 May 2016
Available Online: 26 July 2016

Figures(4)

Two new N-methyladenine-containing diterpenes, nemoechines F (1) and G (2), were isolated from the South China Sea sponge Agelas aff. nemoechinata. The structures were assigned on the basis of spectroscopic date. Compound 2 showed weak activity against Jurkat cell lines with IC₅₀ of 17.1 μmol/L.
- South China Sea,
- Marine sponge,
- Agelas,
- Diterpene alkaloids,
- Cytotoxic
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