Citation: Zhao-Hua Yan, Huan Tian, Dong-Dong Zhao, Hong-Ai Jin, Wei-Sheng Tian. Perfluoroalkanosulfonyl fluoride:A useful reagent for dehydration of aldoximes to nitriles[J]. Chinese Chemical Letters, ;2016, 27(01): 96-98. doi: 10.1016/j.cclet.2015.11.004 shu

Perfluoroalkanosulfonyl fluoride:A useful reagent for dehydration of aldoximes to nitriles

1.
a College of Chemistry, Nanchang University, Nanchang 330031, China;
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b Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Corresponding author: Zhao-Hua Yan, Wei-Sheng Tian,
Received Date: 2 September 2015
Available Online: 3 October 2015
Fund Project: The authors thank the National Natural Science Foundation of China(No. 21362022) for financial support. (No. 21362022)

The reaction of a variety of aldoximes with perfluoroalkanosulfonyl fluoride in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene(DBU) in dichloromethane smoothly generated the corresponding nitriles in 70%-95% yields.
- Perfluoroalkanosulfonyl fluoride,
- Dehydration,
- Aldoximes,
- Nitriles,
- 1,8-Diazabicyclo[5.4.0]undec-7-ene
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