Citation: De-Lin Chen, Feng-Peng Wang, Xiao-Yu Liu. A convergent approach to the tetracyclic core of atisane diterpenes[J]. Chinese Chemical Letters, ;2016, 27(01): 59-62. doi: 10.1016/j.cclet.2015.09.005 shu

A convergent approach to the tetracyclic core of atisane diterpenes

1.
Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu 610041, China

Corresponding author: Feng-Peng Wang, Xiao-Yu Liu,
Received Date: 13 April 2015
Available Online: 9 May 2015
Fund Project: This research was supported by the National Natural Science Foundation of China(No. 81273387). (No. 81273387)

Atisane diterpenes are biologically interesting natural products. We report here a convergent approach to construct the tetracyclic core of the atisane skeleton. The two segments were assembled through a Wittig reaction, while an intramolecular Aldol condensation served as the key step to furnish the tetracyclic skeleton.
- Atisane diterpenes,
- Wittig,
- Intramolecular Aldol,
- Tetracycle
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