Citation: Hui Wang, Jun-Qiu Li, Li-Shan Zhou, Jun Liu, Juan Li, Hong-Mei Qu. Palladium-catalyzed synthesis of 1,2,3,4-tetraalkyl-1,4-diarylbutadienes by cross-coupling of zirconacyclopentadienes with aryl iodides[J]. Chinese Chemical Letters, ;2015, 26(10): 1303-1306. doi: 10.1016/j.cclet.2015.06.012 shu

Palladium-catalyzed synthesis of 1,2,3,4-tetraalkyl-1,4-diarylbutadienes by cross-coupling of zirconacyclopentadienes with aryl iodides

Hui Wang ¹ ,
Jun-Qiu Li ¹ ,
Li-Shan Zhou ² ,
Jun Liu ¹ ,
Juan Li ¹ ,
Hong-Mei Qu ^1,,

1.
1 Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin Key Laboratory of Biological and Pharmaceutical Engineering, Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China;
2.
2 CNOOC Tianjin Chemical Research and Design Institute, Tianjin 300131, China

Corresponding author: Hong-Mei Qu,
Received Date: 7 April 2015
Available Online: 25 May 2015
Fund Project:

A novelmethod for the synthesis of 1, 2, 3, 4-tetraalkyl-1, 4-diarylbutadienes was developed via palladiumcatalyzed cross-coupling of zirconacyclopentadienes with aryl iodides. Equivalent of CuCl was introduced to promote the reaction. The desired products were obtained in good to excellent yields and several of them were reported for the first time.
- Zirconacyclopentadiene,
- Cross-coupling reaction,
- Palladium-catalyzed,
- CuCl,
- 1,2,3,4-Tetraalkyl-1,4-diarylbutadienes
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