Citation: Wei-Mao Zhong, Zhao-Meng Cui, Zhi-Ke Liu, Yan Yang, Da-Rong Wu, Shao-Hua Liu, Hui Long, Han-Dong Sun, Yong-Jun Dang, Wei-Lie Xiao. Three minor new compounds from the aerial parts of Leonurus japonicus[J]. Chinese Chemical Letters, ;2015, 26(8): 1000-1003. doi: 10.1016/j.cclet.2015.05.004 shu

Three minor new compounds from the aerial parts of Leonurus japonicus

Wei-Mao Zhong ^a,d ,
Zhao-Meng Cui ^b ,
Zhi-Ke Liu ^a,d ,
Yan Yang ^a ,
Da-Rong Wu ^c ,
Shao-Hua Liu ^c ,
Hui Long ^a,d ,
Han-Dong Sun ^a ,
Yong-Jun Dang ^b,, ,
Wei-Lie Xiao ^a,,

1.
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
2.
b Key Laboratory of Molecular Medicine, Ministry of Education, and Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, Shanghai 200032, China;
c Chengdu No.
c Chengdu No. 1 Pharmaceutical Group Co., Ltd., Chengdu 610031, China;
4.
d University of Chinese Academy of Sciences, Beijing 100049, China

Corresponding author: Yong-Jun Dang, Wei-Lie Xiao,
Received Date: 25 January 2015
Available Online: 15 April 2015
Fund Project: the project sponsored by SRF for ROCS, SEM to W.L. Xiao. (No. 2013BAI11B02)

Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one new labdane diterpenoid, leojaponin D (1) and two new ionone derivatives, leojaponones A and B (2 and 3), together with seven known diterpenoids (4-10). Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and by comparison with data reported in the literature. Selected isolates were evaluated their effects on Jurkat IL2 secretion.
- Leonurus japonicus,
- Diterpenoid,
- Ionone derivative,
- Jurkat IL2 secretion
1. [1]
  [1] The Editorial Board of Flora of China, Flora of China, Science Press, Beijing, 1977, pp. 505-511.
2. [2]
  [2] S.Y. Hu, A contribution to our knowledge of Leonurus L., I-mu-ts'ao, the Chinese motherwort, Am. J. Chin. Med. 4 (1976) 219-237.
3. [3]
  [3] L.H. Shen, S.L. Wang, Research progress on Leonurus Heterophyllus Sweet, Med. Plant. 1 (2010) 48-51.
4. [4]
  [4] Z.K. Liu, D.R. Wu, Y.M. Shi, et al., Three new diterpenoids from Leonurus japonicus, Chin. Chem. Lett. 25 (2014) 677-679.
5. [5]
  [5] P.M. Giang, P.T. Son, K. Matsunami, H. Otsuka, New labdane-type diterpenoids from Leonurus heterophyllus Sw, Chem. Pharm. Bull. 53 (2005) 938-941.
6. [6]
  [6] A.A. Hussein, M.J.J. Meyer, B. Rodríguez, Complete ¹H and ¹³C NMR assignments of three labdane diterpenoids isolated from Leonotis ocymifolia and six other related compounds, Magn. Reson. Chem. 41 (2003) 147-151.
7. [7]
  [7] P.M. Hon, E.S. Wang, S.K.M. Lam, et al., Preleoheterin and leoheterin, two labdane diterpenes from Leonurus heterophyllus, Phytochemistry 33 (1993) 639-641.
8. [8]
  [8] H.Q. Gong, R. Wang, Y.P. Shi, New labdane-type diterpenoids from Leonurus heterophyllus, Helv. Chim. Acta 95 (2012) 618-625.
9. [9]
  [9] A.H. Zhao, R.T. Li, B. Jiang, et al., Three new compounds from Isodon melissoides, J. Asian Nat. Prod. Res. 7 (2005) 151-156.
10. [10]
  [10] J. Shitamoto, K. Matsunami, H. Otsuka, T. Shinzato, Y. Takeda, Crotlionsides A-C, three new megastigmane glucosides, two new pterocarpan glucosides and a chalcone C-glucoside from the whole plants of Crotalaria zanzibarica, Chem. Phar. Bull. 58 (2010) 1026-1032.
11. [11]
  [11] S.P. Ding, J.C. Li, J. Xu, L.G. Mao, Study on the mechanism of regulation on peritoneal lymphatic stomata with Chinese herbal medicine, World J. Gastroenterol. 8 (2002) 188-192.
12. [12]
  [12] Y.R. Ren, F. Pan, S. Parvez, et al., Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes, PLoS ONE 12 (2008) e4009.
1. [1]
  Luyan Shi , Ke Zhu , Yuting Yang , Qinrui Liang , Qimin Peng , Shuqing Zhou , Tayirjan Taylor Isimjan , Xiulin Yang . Phytic acid-derivative Co₂B-CoPO_x coralloidal structure with delicate boron vacancy for enhanced hydrogen generation from sodium borohydride. Chinese Chemical Letters, 2024, 35(4): 109222-. doi: 10.1016/j.cclet.2023.109222
2. [2]
  Junjun Huang , Ran Chen , Yajian Huang , Hang Zhang , Anran Zheng , Qing Xiao , Dan Wu , Ruxia Duan , Zhi Zhou , Fei He , Wei Yi . Discovery of an enantiopure N-[2-hydroxy-3-phenyl piperazine propyl]-aromatic carboxamide derivative as highly selective α_1D/1A-adrenoceptor antagonist and homology modelling. Chinese Chemical Letters, 2024, 35(11): 109594-. doi: 10.1016/j.cclet.2024.109594
3. [3]
  Yuanjiao Liu , Xiaoyang Zhao , Songyao Zhang , Yi Wang , Yutuo Zheng , Xinrui Miao , Wenli Deng . Site-selection and recognition of aromatic carboxylic acid in response to coronene and pyridine derivative. Chinese Chemical Letters, 2024, 35(8): 109404-. doi: 10.1016/j.cclet.2023.109404
4. [4]
  An Lu , Yuhao Guo , Yi Yan , Lin Zhai , Xiangyu Wang , Weiran Cao , Zijie Li , Zhixia Zhao , Yujie Shi , Yuanjun Zhu , Xiaoyan Liu , Huining He , Zhiyu Wang , Jian-Cheng Wang . Nanomedicine integrating the lipidic derivative of 5-fluorouracil, miriplatin and PD-L1 siRNA for enhancing tumor therapy. Chinese Chemical Letters, 2024, 35(6): 108928-. doi: 10.1016/j.cclet.2023.108928
5. [5]
  Junying Zhang , Ruochen Li , Haihua Wang , Wenbing Kang , Xing-Dong Xu . Photo-induced tunable luminescence from an aggregated amphiphilic ethylene-pyrene derivative in aqueous media. Chinese Chemical Letters, 2024, 35(6): 109216-. doi: 10.1016/j.cclet.2023.109216
6. [6]
  Lu-Lu He , Lan-Tu Xiong , Xin Wang , Yu-Zhen Li , Jia-Bao Li , Yu Shi , Xin Deng , Zi-Ning Cui . Application of inhibitors targeting the type III secretion system in phytopathogenic bacteria. Chinese Chemical Letters, 2025, 36(4): 110044-. doi: 10.1016/j.cclet.2024.110044
7. [7]
  Boyuan Hu , Jian Zhang , Yulin Yang , Yayu Dong , Jiaqi Wang , Wei Wang , Kaifeng Lin , Debin Xia . Dual-functional POM@IL complex modulate hole transport layer properties and interfacial charge dynamics for highly efficient and stable perovskite solar cells. Chinese Chemical Letters, 2024, 35(7): 108933-. doi: 10.1016/j.cclet.2023.108933
8. [8]
  Haojie Duan , Hejingying Niu , Lina Gan , Xiaodi Duan , Shuo Shi , Li Li . Reinterpret the heterogeneous reaction of α-Fe₂O₃ and NO₂ with 2D-COS: The role of SDS, UV and SO₂. Chinese Chemical Letters, 2024, 35(6): 109038-. doi: 10.1016/j.cclet.2023.109038
9. [9]
  Renshu Huang , Jinli Chen , Xingfa Chen , Tianqi Yu , Huyi Yu , Kaien Li , Bin Li , Shibin Yin . Synergized oxygen vacancies with Mn2O3@CeO2 heterojunction as high current density catalysts for Li–O2 batteries. Chinese Journal of Structural Chemistry, 2023, 42(11): 100171-100171. doi: 10.1016/j.cjsc.2023.100171
10. [10]
  Shengwen Guan , Zhaotong Wei , Ningxu Han , Yude Wei , Bin Xu , Ming Wang , Junjuan Shi . Construction of metallo-complexes with 2,2′:6′,2″-terpyridine substituted triphenylamine in different modified positions and their photophysical properties. Chinese Chemical Letters, 2024, 35(7): 109348-. doi: 10.1016/j.cclet.2023.109348
11. [11]
  Maomao Liu , Guizeng Liang , Ningce Zhang , Tao Li , Lipeng Diao , Ping Lu , Xiaoliang Zhao , Daohao Li , Dongjiang Yang . Electron-rich Ni2+ in Ni3S2 boosting electrocatalytic CO2 reduction to formate and syngas. Chinese Journal of Structural Chemistry, 2024, 43(8): 100359-100359. doi: 10.1016/j.cjsc.2024.100359
12. [12]
  Yongheng Ren , Yang Chen , Hongwei Chen , Lu Zhang , Jiangfeng Yang , Qi Shi , Lin-Bing Sun , Jinping Li , Libo Li . Electrostatically driven kinetic Inverse CO2/C2H2 separation in LTA-type zeolites. Chinese Journal of Structural Chemistry, 2024, 43(10): 100394-100394. doi: 10.1016/j.cjsc.2024.100394
13. [13]
  Huirong Chen , Yingzhi He , Yan Han , Jianbo Hu , Jiantang Li , Yunjia Jiang , Basem Keshta , Lingyao Wang , Yuanbin Zhang . A new SIFSIX anion pillared cage MOF with crs topological structure for efficient C2H2/CO2 separation. Chinese Journal of Structural Chemistry, 2025, 44(2): 100508-100508. doi: 10.1016/j.cjsc.2024.100508
14. [14]
  Cailiang Yue , Nan Sun , Yixing Qiu , Linlin Zhu , Zhiling Du , Fuqiang Liu . A direct Z-scheme 0D α-Fe₂O₃/TiO₂ heterojunction for enhanced photo-Fenton activity with low H₂O₂ consumption. Chinese Chemical Letters, 2024, 35(12): 109698-. doi: 10.1016/j.cclet.2024.109698
15. [15]
  Liyong Ding , Zhenhua Pan , Qian Wang . 2D photocatalysts for hydrogen peroxide synthesis. Chinese Chemical Letters, 2024, 35(12): 110125-. doi: 10.1016/j.cclet.2024.110125
16. [16]
  Wenlong LI , Xinyu JIA , Jie LING , Mengdan MA , Anning ZHOU . Photothermal catalytic CO₂ hydrogenation over a Mg-doped In₂O_3-x catalyst. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 919-929. doi: 10.11862/CJIC.20230421
17. [17]
  Xiangyuan Zhao , Jinjin Wang , Jinzhao Kang , Xiaomei Wang , Hong Yu , Cheng-Feng Du . Ni nanoparticles anchoring on vacuum treated Mo2TiC2Tx MXene for enhanced hydrogen evolution activity. Chinese Journal of Structural Chemistry, 2023, 42(10): 100159-100159. doi: 10.1016/j.cjsc.2023.100159
18. [18]
  Zizhuo Liang , Fuming Du , Ning Zhao , Xiangxin Guo . Revealing the reason for the unsuccessful fabrication of Li3Zr2Si2PO12 by solid state reaction. Chinese Journal of Structural Chemistry, 2023, 42(11): 100108-100108. doi: 10.1016/j.cjsc.2023.100108
19. [19]
  Anqiu LIU , Long LIN , Dezhi ZHANG , Junyu LEI , Kefeng WANG , Wei ZHANG , Junpeng ZHUANG , Haijun HAO . Synthesis, structures, and catalytic activity of aluminum and zinc complexes chelated by 2-((2,6-dimethylphenyl)amino)ethanolate. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 791-798. doi: 10.11862/CJIC.20230424
20. [20]
  Yubang Li , Xixi Hu , Daiqian Xie . The microscopic formation mechanism of O + H2 products from photodissociation of H2O. Chinese Journal of Structural Chemistry, 2024, 43(5): 100274-100274. doi: 10.1016/j.cjsc.2024.100274

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(686)
HTML views(5)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142