Citation: Chang-Lei Liu, Gang Wu, Si-Chong Chen, Jiao You, Yu-Zhong Wang. Crystallization induced micellization of poly(p-dioxanone)-block-polyethylene glycol diblock copolymer functionalized with pyrene moiety[J]. Chinese Chemical Letters, ;2014, 25(10): 1311-1317. doi: 10.1016/j.cclet.2014.07.009 shu

Crystallization induced micellization of poly(p-dioxanone)-block-polyethylene glycol diblock copolymer functionalized with pyrene moiety

1.
Center for Degradable and Flame-Retardant Polymeric Materials, State Key Laboratory of Polymer Materials Engineering, College of Chemistry, National Engineering Laboratory of Eco-Friendly Polymeric Materials (Sichuan), Sichuan University, Chengdu 610064, China

Corresponding author: Si-Chong Chen, Yu-Zhong Wang,
Received Date: 20 May 2014
Available Online: 10 July 2014
Fund Project:

Poly(p-dioxanone)-block-polyethylene glycol diblock copolymers functionalized with pyrene moieties (Py-PPDO-b-PEG) at the chain ends of PPDO blocks were synthesized for preparing anisotropic micelles with improved stability. The micellization and crystallization of the copolymers were investigated by nano differential scanning calorimetry (Nano DSC), transmission electron microscopy (TEM), UV-vis spectrophotometery, fluorophotometer, and dynamic light scattering (DLS), respectively. The results indicated that the aggregation of pyrene induced by intermolecular interaction lead to micellization of Py-PPDO-b-PEG at much lower concentrations than those of PPDO-b-PEG copolymers without pyrene moieties. The aggregation of pyrene moieties may also serve as nucleation agent and therefore enhance the crystallization rate of PPDO blocks. Fluorescence measurements by using Nile Red as the fluorescent agent indicated that the micelles of Py-PPDO-b-PEG have high stability and load capacity for hydrophobic molecules.
- Crystallization induced micellization,
- Micelle stability,
- Pyrene moiety,
- Poly(p-dioxanone)
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沈阳化工大学材料科学与工程学院沈阳 110142