Citation: Qiu-Jin Peng, Jun-Jiao Yang. Preparation and chromatographic characteristics of a novel 2,6-dimethyl-β-CD bonded HPLC chiral stationary phase[J]. Chinese Chemical Letters, ;2014, 25(11): 1416-1418. doi: 10.1016/j.cclet.2014.05.052 shu

Preparation and chromatographic characteristics of a novel 2,6-dimethyl-β-CD bonded HPLC chiral stationary phase

Qiu-Jin Peng ,
Jun-Jiao Yang ^,

1.
Beijing Key Laboratory of Environmentally Harmful Chemical Analysis, Beijing University of Chemical Technology, Beijing 100029, China

Corresponding author: Jun-Jiao Yang,
Received Date: 24 March 2014
Available Online: 19 May 2014

A novel 2,6-dimethyl-β-CD bonded and silica based HPLC chiral stationary phase (CSP) was prepared. The diphenylmethane diisocyanate (MDI) was applied for the first time in the immobilization of 2, 6-dimethyl-β-CD onto the surface of aminized silica gel undermild conditions. The compositematerials obtained were used as the CSP for chiral separation processes and this kind of CSP exhibits good enantioselectivity for a variety of chiral compounds under reversed-phase conditions.
- 2,6-Dimethyl-β-cyclodextrin,
- Chiral stationary phase (CSP),
- Diphenylmethane diisocyanate (MDI),
- Chiral separation
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沈阳化工大学材料科学与工程学院沈阳 110142