Citation: Shuang-Yong Lin, Hui-Jun Zhu, Wen-Jian Xu, Gui-Mei Wang, Nan-Yan Fu. A squaraine based fl uorescent probe for mercury ion via coordination induced deaggregation signaling[J]. Chinese Chemical Letters, ;2014, 25(9): 1291-1295. doi: 10.1016/j.cclet.2014.04.027 shu

A squaraine based fl uorescent probe for mercury ion via coordination induced deaggregation signaling

1.
Key Laboratory of Analysis and Detection for Food Safety, Ministry of Education & Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry and Chemical Engineering, and Department of Chemistry, Fuzhou University, Fuzhou 350108, China

Corresponding author: Nan-Yan Fu,
Received Date: 3 January 2014
Available Online: 9 April 2014
Fund Project: This work was financially supported by the National Science Foundation for Fostering Talents in Basic Research of the National Natural Science Foundation of China (No. J1103303) (No. J1103303) the National Natural Science Foundation of China (No. 20702005) (No. 20702005) Funding (Type A) from Fujian Education Department, PR China (Nos. JA12038 and JA13043) (No. 2013Y0062)the Science and Technology Development Fund of Fuzhou University, China (No. 600902). (Type A)

Due to the high affinity between dithiocarbamate (DTC) and Hg²⁺, a fluorescent probe based on squaraine chromophore with DTC side arm for Hg²⁺ via coordination induced deaggregation signaling has been designed and synthesized. Squaraine has a high tendency to aggregate in aqueous solution, and such self-aggregation usually results in a dramatic absorption spectral broadening with fluorescence emission quenching. The combination of the DTC side arm of the probe with Hg²⁺ induces steric hindrance, leading to the deaggregation of the dye complex, companying with a fluorescence emission restoration. In EtOH-H₂O (20:80, v/v) solution, this "turn on" fluorescent probe has high selectivity and sensitivity toward Hg²⁺ over other metal ions, and the limit of detection for Hg²⁺ was estimated as 2.19×10^-8mol/L by 3σ/k.
- Squaraine dye,
- Fluorescent probe,
- Coordination induced deaggregation,
- Mercury ion detection
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