Citation: Xiao-Dong Xia, Hao-Wen Huang. Using unmodifi ed Au nanoparticles as colorimetric probes for TNT based on their competitive reactions with melamine[J]. Chinese Chemical Letters, ;2014, 25(9): 1271-1274. doi: 10.1016/j.cclet.2014.03.008 shu

Using unmodifi ed Au nanoparticles as colorimetric probes for TNT based on their competitive reactions with melamine

Xiao-Dong Xia ^, ,
Hao-Wen Huang

1.
Key Laboratory of Theoretical Chemistry and Molecular Simulation, Minister of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China

Corresponding author: Xiao-Dong Xia,
Received Date: 14 January 2014
Available Online: 28 February 2014
Fund Project: This work is supported by National Natural Science Foundation of China (No. 21375036) (No. 21375036)

Gold nanoparticles (Au NPs) can serve as visualized colorimetric probes for various targets and modification-free sensing strategies are preferred. The donor-acceptor interaction between the electron-rich melamine (MA) and the electron-deficient trinitrotoluene (TNT) allows formation of a supramolecule in aqueous solution. Melamine alone makes the initially individual reddish Au NPs aggregate into gray/blue Au NP assemblies due tomelamine forming multiple ligand sites toward the Au NPs. Interestingly, the preformed supramolecule of MA-TNT disenables aggregation of the Au NPs. Therefore the unmodified Au NPs provide facile colorimetric probes for TNT detection in aqueous solution. Rapid identification of TNT is established by naked eye inspection. By using spectrophotometer tools, quantification of TNT is accomplished with a linear range of 80 μmol L^-1 to 1.2 μmol L^-1 and a limit of detection (LOD) of 27 μmol L^-1. In contrast to previous strategy with surface-modified Au NPs, here a modification-free sensing strategy for TNT assay has been developed with greater convenience, rapidity, and cost-effectiveness.
- Electron donor-acceptor interaction,
- Gold nanoparticles,
- Melamine,
- Trinitrotoluene,
- Colorimetry
1. [1]
  [1] D.G. Gehring, J.E. Shirk, Separation and determination of trinitrotoluene isomers by gas chromatography, Anal. Chem. 39 (1967) 1315-1318.
2. [2]
  [2] P. Sulzer, F. Petersson, B. Agarwal, et al., Proton transfer reaction mass spectrometry and the unambiguous real-time detection of 2,4,6 trinitrotoluene, Anal. Chem. 84 (2012) 4161-4166.
3. [3]
  [3] J. Yinon, H.G. Boettger, W.P. Weber, Negative ion mass spectrometry. New analytical method for detection of trinitrotoluene, Anal. Chem. 44 (1972) 2235-2237.
4. [4]
  [4] Y. Xia, L. Song, C. Zhu, Turn-on and near-infrared fluorescent sensing for 2,4,6-trinitrotoluene based on hybrid (gold nanorod)-(quantum dots) assembly, Anal. Chem. 83 (2011) 1401-1407.
5. [5]
  [5] H. Zhou, Z. Zhang, C. Jiang, et al., Trinitrotoluene explosive lights up ultrahigh raman scattering of nonresonant molecule on a top-closed silver nanotube array, Anal. Chem. 83 (2011) 6913-6917.
6. [6]
  [6] W.S. Zou, D. Sheng, X. Ge, J.Q. Qiao, H.Z. Lian, Room-temperature phosphorescence chemosensor and rayleigh scattering chemodosimeter dual-recognition probe for 2,4,6-trinitrotoluene based on manganese-doped ZnS quantum dots, Anal. Chem. 83 (2011) 30-37.
7. [7]
  [7] Y.Q. Wang, W.S. Zou, 3-Aminopropyltriethoxysilane-functionalized manganese doped ZnS quantum dots for room-temperature phosphorescence sensing ultratrace 2,4,6-trinitrotoluene in aqueous solution, Talanta 85 (2011) 469-475.
8. [8]
  [8] L. Fan, Y. Hu, X. Wang, et al., Fluorescence resonance energy transfer quenching at the surface of graphene quantum dots for ultrasensitive detection of TNT, Talanta 101 (2012) 192-197.
9. [9]
  [9] S.S.R. Dasary, A.K. Singh, D. Senapati, H. Yu, P.C. Ray, Gold nanoparticle based label-free SERS probe for ultrasensitive and selective detection of trinitrotoluene, J. Am. Chem. Soc. 131 (2009) 13806-13812.
10. [10]
  [10] L. Feng, H. Li, Y. Qu, C. Lu, Detection of TNT based on conjugated polymer encapsulated in mesoporous silica nanoparticles through FRET, Chem. Commun. 48 (2012) 4633-4635.
11. [11]
  [11] A. Mathew, P.R. Sajanlal, T. Pradeep, Selective visual detection of TNT at the subzeptomole level, Angew. Chem. Int. Ed. 51 (2012) 9596-9600.
12. [12]
  [12] E.R. Goldman, I.L. Medintz, J.L. Whitley, et al., A hybrid quantum dot-antibody fragment fluorescence resonance energy transfer-based TNT sensor, J. Am. Chem. Soc. 127 (2005) 6744-6751.
13. [13]
  [13] J.J. Feng, H. Guo, Y.F. Li, et al., Single molecular functionalized gold nanoparticles for hydrogen-bonding recognition and colorimetric detection of dopamine with high sensitivity and selectivity, ACS Appl. Mater. Interfaces 5 (2013) 1226-1231.
14. [14]
  [14] T. Lou, Z. Chen, Y. Wang, L. Chen, Blue-to-red colorimetric sensing strategy for Hg²⁺ and Ag⁺¹ via redox-regulated surface chemistry of gold nanoparticles, ACS Appl. Mater. Interfaces 3 (2011) 1568-1573.
15. [15]
  [15] J.H. Lin, C.W. Chang, Z.H. Wu, W.L. Tseng, Colorimetric assay for S-adenosylhomocysteine hydrolase activity and inhibition using fluorosurfactant-capped gold nanoparticles, Anal. Chem. 82 (2010) 8775-8779.
16. [16]
  [16] Z. Zeng, S. Mizukami, K. Kikuchi, Simple and real-time colorimetric assay for glycosidases activity using functionalized gold nanoparticles and its application for inhibitor screening, Anal. Chem. 84 (2012) 9089-9095.
17. [17]
  [17] Y. Jiang, H. Zhao, N. Zhu, et al., A simple assay for direct colorimetric visualization of trinitrotoluene at picomolar levels using gold nanoparticles, Angew. Chem. Int. Ed. 47 (2008) 8601-8604.
18. [18]
  [18] D. Lin, H. Liu, K. Qian, et al., Ultrasensitive optical detection of trinitrotoluene by ethylenediamine-capped gold nanoparticles, Anal. Chim. Acta 744 (2012) 92-98.
19. [19]
  [19] S. Link, M.A. El-Sayed, Spectral properties and relaxation dynamics of surface plasmon electronic oscillations in gold and silver nanodots and nanorods, J. Phys. Chem. B 103 (1999) 8410-8426.
20. [20]
  [20] B. Mukherjee, A.J. Pal, Write-once-read-many-times (WORM) memory applications in a monolayer of donor/acceptor supramolecule, Chem. Mater. 19 (2007) 1382-1387.
21. [21]
  [21] J. Rosenthal, J.M. Hodgkiss, E.R. Young, D.G. Nocera, Spectroscopic determination of proton position in the proton-coupled electron transfer pathways of donor-acceptor supramolecule assemblies, J. Am. Chem. Soc. 128 (2006) 10474-10483.
22. [22]
  [22] K.B. Landenberger, A.J. Matzger, Cocrystal engineering of a prototype energetic material: supramolecular chemistry of 2,4,6-trinitrotoluene, Cryst. Growth Des. 10 (2010) 5341-5347.
23. [23]
  [23] P.V. Kamat, Photophysical, photochemical and photocatalytic aspects of metal nanoparticles, J. Phys. Chem. B 106 (2002) 7729-7744.
24. [24]
  [24] W. Chen, H.H. Deng, L. Hong, et al., Bare gold nanoparticles as facile and sensitive colorimetric probe for melamine detection, Analyst 137 (2012) 5382-5386.
25. [25]
  [25] H. Chi, B. Liu, G. Guan, Z. Zhang, M.Y. Han, A simple, reliable and sensitive colorimetric visualization of melamine in milk by unmodified gold nanoparticles, Analyst 135 (2010) 1070-1075.
26. [26]
  [26] L. Li, B. Li, D. Cheng, L. Mao, Visual detection of melamine in raw milk using gold nanoparticles as colorimetric probe, Food Chem. 122 (2010) 895-900.
27. [27]
  [27] X. Su, R. Kanjanawarut, Control of metal nanoparticles aggregation and dispersion by PNA and PNA-DNA complexes, and its application for colorimetric DNA detection, ACS Nano 3 (2009) 2751-2759.
28. [28]
  [28] S. Hong, I. Choi, S. Lee, et al., Sensitive and colorimetric detection of the structural evolution of superoxide dismutase with gold nanoparticles, Anal. Chem. 81 (2009) 1378-1382.
29. [29]
  [29] R. Kanjanawarut, X. Su, Colorimetric detection of DNA using unmodified metallic nanoparticles and peptide nucleic acid probes, Anal. Chem. 81 (2009) 6122-6129.
30. [30]
  [30] S.H. Wu, Y.S. Wu, C.H. Chen, Colorimetric sensitivity of gold nanoparticles: minimizing interparticular repulsion as a general approach, Anal. Chem. 80 (2008) 6560-6566.
31. [31]
  [31] Z. Wang, R. Lévy, D.G. Fernig, M. Brust, Kinase-catalyzed modification of gold nanoparticles: a new approach to colorimetric kinase activity screening, J. Am. Chem. Soc. 128 (2006) 2214-2215.
32. [32]
  [32] M. Wang, X. Gu, G. Zhang, D. Zhang, D. Zhu, Continuous colorimetric assay for acetylcholinesterase and inhibitor screening with gold nanoparticles, Langmuir 25 (2009) 2504-2507.
1. [1]
  Xiangqian Cao , Chenkai Yang , Xiaodong Zhu , Mengxin Zhao , Yilin Yan , Zhengnan Huang , Jinming Cai , Jingming Zhuang , Shengzhou Li , Wei Li , Bing Shen . Synergistic enhancement of chemotherapy for bladder cancer by photothermal dual-sensitive nanosystem with gold nanoparticles and PNIPAM. Chinese Chemical Letters, 2024, 35(8): 109199-. doi: 10.1016/j.cclet.2023.109199
2. [2]
  Caixia Zhu , Qing Hong , Kaiyuan Wang , Yanfei Shen , Songqin Liu , Yuanjian Zhang . Single nanozyme-based colorimetric biosensor for dopamine with enhanced selectivity via reactivity of oxidation intermediates. Chinese Chemical Letters, 2024, 35(10): 109560-. doi: 10.1016/j.cclet.2024.109560
3. [3]
  Yiyang Shen , Zhen Zhang , Ruyi Liang , Tongbo Wu . Unraveling the interplay of DNAzyme and interfacial factors for enhanced biosensing. Chinese Chemical Letters, 2024, 35(12): 109638-. doi: 10.1016/j.cclet.2024.109638
4. [4]
  Rong-Nan Yi , Wei-Min He . Electron donor-acceptor complex enabled arylation of dithiocarbamate anions with thianthrenium salts under aqueous micellar conditions. Chinese Chemical Letters, 2024, 35(11): 110194-. doi: 10.1016/j.cclet.2024.110194
5. [5]
  Hongping Zhao , Weiming Yuan . Merging catalytic electron donor-acceptor complex and copper catalysis: Enantioselective radical carbocyanation of alkenes. Chinese Chemical Letters, 2025, 36(10): 110894-. doi: 10.1016/j.cclet.2025.110894
6. [6]
  Shuqi Chen , Cankun Zhang , Xiaonuo Dong , Hui-Jun Zhang , Jianbin Lin . Synthesis and photophysical properties of alternating donor-acceptor conjugated nanorings. Chinese Chemical Letters, 2025, 36(6): 110354-. doi: 10.1016/j.cclet.2024.110354
7. [7]
  Shaonan Tian , Yu Zhang , Qing Zeng , Junyu Zhong , Hui Liu , Lin Xu , Jun Yang . Core-shell gold-copper nanoparticles: Evolution of copper shells on gold cores at different gold/copper precursor ratios. Chinese Journal of Structural Chemistry, 2023, 42(11): 100160-100160. doi: 10.1016/j.cjsc.2023.100160
8. [8]
  Zhi Li , Wenpei Li , Shaoping Jiang , Chuan Hu , Yuanyu Huang , Maxim Shevtsov , Huile Gao , Shaobo Ruan . Legumain-triggered aggregable gold nanoparticles for enhanced intratumoral retention. Chinese Chemical Letters, 2024, 35(7): 109150-. doi: 10.1016/j.cclet.2023.109150
9. [9]
  Zhaoyue Lü , Tiantian Chai , Yichao Jin , Xiao Wang , Ye Zou , Lijiang Zhang , Jiankang Feng , Mengtong Zhang , Shuo Wang , Chichong Lu , Guofan Jin . Asymmetrical carbazole-benzonitrile-based TADF emitters designed by alternate donor-acceptor strategy. Chinese Chemical Letters, 2025, 36(6): 110817-. doi: 10.1016/j.cclet.2025.110817
10. [10]
  Xinyi Zhao , Yuai Duan , Zihan Liu , Hua Geng , Yaping Li , Zhongfeng Li , Tianyu Han . Mapping sweat pores for biometric identification based on a donor-acceptor hydrophilic fluorescent probe. Chinese Chemical Letters, 2025, 36(8): 110617-. doi: 10.1016/j.cclet.2024.110617
11. [11]
  Jiawei Li , Cheng Chen , Mingyan Wu . Donor-acceptor type organic cocrystals for deep-red circularly polarized luminescence and two-photon excited emission. Chinese Journal of Structural Chemistry, 2025, 44(3): 100513-100513. doi: 10.1016/j.cjsc.2025.100513
12. [12]
  Zhijuan Niu , Peizhe Sun , Kwangnak Koh , Changping Li . Ultrasensitive electrochemical sensor based on para-sulfonatocalix[4]arene functionalized gold nanoparticles for sulfamethazine detection. Chinese Chemical Letters, 2025, 36(11): 110844-. doi: 10.1016/j.cclet.2025.110844
13. [13]
  Rong-Nan Yi , Zi-Jian Zhao , Wei-Min He . Photoinduced gold-catalyzed cross-couplings. Chinese Chemical Letters, 2025, 36(7): 111070-. doi: 10.1016/j.cclet.2025.111070
14. [14]
  Guixu Pan , Zhiling Xia , Ning Wang , Hejia Sun , Zhaoqi Guo , Yunfeng Li , Xin Li . Preparation of high-efficient donor-π-acceptor system with crystalline g-C3N4 as charge transfer module for enhanced photocatalytic hydrogen evolution. Chinese Journal of Structural Chemistry, 2024, 43(12): 100463-100463. doi: 10.1016/j.cjsc.2024.100463
15. [15]
  Bharathi Natarajan , Palanisamy Kannan , Longhua Guo . Metallic nanoparticles for visual sensing: Design, mechanism, and application. Chinese Journal of Structural Chemistry, 2024, 43(9): 100349-100349. doi: 10.1016/j.cjsc.2024.100349
16. [16]
  Jialin Guo , Mingrui Gu , Yahui Chen , Tao Xiong , Yiyang Zhang , Simin Chen , Mingle Li , Xiaoqiang Chen , Xiaojun Peng . Nucleic acid delivery by lipid nanoparticles for organ targeting. Chinese Chemical Letters, 2025, 36(11): 110849-. doi: 10.1016/j.cclet.2025.110849
17. [17]
  Min Huang , Ru Cheng , Shuai Wen , Liangtong Li , Jie Gao , Xiaohui Zhao , Chunmei Li , Hongyan Zou , Jian Wang . Ultrasensitive detection of microRNA-21 in human serum based on the confinement effect enhanced chemical etching of gold nanorods. Chinese Chemical Letters, 2024, 35(9): 109379-. doi: 10.1016/j.cclet.2023.109379
18. [18]
  Ji Liu , Dongsheng He , Tianjiao Hao , Yumin Hu , Yan Zhao , Zhen Li , Chang Liu , Daquan Chen , Qiyue Wang , Xiaofei Xin , Yan Shen . Gold mineralized "hybrid nanozyme bomb" for NIR-II triggered tumor effective permeation and cocktail therapy. Chinese Chemical Letters, 2024, 35(9): 109296-. doi: 10.1016/j.cclet.2023.109296
19. [19]
  Ya-Wen Zhang , Ming-Ming Gan , Li-Ying Sun , Ying-Feng Han . Supramolecular dinuclear silver(I) and gold(I) tetracarbene metallacycles and fluorescence sensing of penicillamine. Chinese Journal of Structural Chemistry, 2024, 43(9): 100356-100356. doi: 10.1016/j.cjsc.2024.100356
20. [20]
  Chong-Yang Shi , Jian-Xing Gong , Zhen Li , Chao Shu , Long-Wu Ye , Qing Sun , Bo Zhou , Xin-Qi Zhu . Gold-catalyzed intermolecular amination of allyl azides with ynamides: Efficient construction of 3-azabicyclo[3.1.0] scaffold. Chinese Chemical Letters, 2025, 36(2): 109895-. doi: 10.1016/j.cclet.2024.109895

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(1169)
HTML views(16)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142