Citation: Lei-Xiao Yu, Yang Liu, Si-Chong Chen, Yue Guan, Yu-Zhong Wang. Reversible photoswitching aggregation and dissolution of spiropyranfunctionalized copolymer and light-responsive FRET process[J]. Chinese Chemical Letters, ;2014, 25(3): 389-396. doi: 10.1016/j.cclet.2013.12.014 shu

Reversible photoswitching aggregation and dissolution of spiropyranfunctionalized copolymer and light-responsive FRET process

1.
Center for Degradable and Flame-Retardant Polymeric Materials, State Key Laboratory of Polymer Materials Engineering, College of Chemistry, National Engineering Laboratory of Eco-Friendly Polymeric Materials (Sichuan), Sichuan University, Chengdu 610064, China

Corresponding author: Si-Chong Chen, Yu-Zhong Wang,
Received Date: 11 November 2013
Available Online: 6 December 2013
Fund Project:

Well-defined, reversibly light-responsive amphiphilic diblock copolymer grafted with spiropyran, was prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization. The copolymer self-assembles into polymeric micelles in water and exhibits reversible dissolution and re-aggregation characteristics upon ultraviolet (UV) and visible (Vis)-light irradiation. The fluorescence response of spiropyran immobilized onto the copolymer was light switchable. When nitrobenzoxadiazolyl derivative (NBD) dyes are encapsulated into the core of the micelles, a reversible, light-responsive, dual-color fluorescence resonance energy transfer (FRET) system is constructed and processed, which is well regulated by alternatively UV/vis irradiation. We anticipate these photoswitchable and FRET lighting up nanoparticles will be useful in drug delivery and cell imaging or tracking synchronously.
- RAFT polymerization,
- Spiropyran,
- Light-responsive,
- Self-assemble,
- Fluorescence resonance energy transfer,
- (FRET)
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