Citation: Yang Song, Wei Yuan, Yu Luo, Wei Lu. A new synthetic approach to phosphatidylethanolamine[J]. Chinese Chemical Letters, ;2012, 23(2): 154-156. doi: 10.1016/j.cclet.2011.10.020 shu

A new synthetic approach to phosphatidylethanolamine

Yang Song ^a, ,
Wei Yuan ^a ,
Yu Luo ^a ,
Wei Lu ^b

a Department of Chemistry, East China Normal University, Shanghai 200062, China;
b Institute of Drug Discovery and Development, East China Normal University, Shanghai 200062, China

Received Date: 23 August 2011

Fund Project: We gratefully acknowledge the financial support from the National Natural Science Foundation of China (No. 305722321) and Shanghai Municipal Natural Science Foundation (No. 10ZR1409600). We also thank Lab of Organic Functional Molecules, the Sino-French Institute of ECNU for supports.

A new synthetic method for phosphatidylethanolamine head group was developed via ring-opening of cyclic dioxaphospholane 2 with sodium azide and subsequent hydrogenation. The advantage of this strategy included short reaction steps, readily available materials and good yields.
- Phosphatidylethanolamine,
- Synthesis
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