引用本文:
Jing Duan, Zhi Yong Guo. Development of a test strip based on DNA-functionalized gold nanoparticles for rapid detection of mercury(Ⅱ) ions[J]. Chinese Chemical Letters,
2012, 23(2): 225-228.
doi:
10.1016/j.cclet.2011.09.025
Citation: Jing Duan, Zhi Yong Guo. Development of a test strip based on DNA-functionalized gold nanoparticles for rapid detection of mercury(Ⅱ) ions[J]. Chinese Chemical Letters, 2012, 23(2): 225-228. doi: 10.1016/j.cclet.2011.09.025
Citation: Jing Duan, Zhi Yong Guo. Development of a test strip based on DNA-functionalized gold nanoparticles for rapid detection of mercury(Ⅱ) ions[J]. Chinese Chemical Letters, 2012, 23(2): 225-228. doi: 10.1016/j.cclet.2011.09.025
Development of a test strip based on DNA-functionalized gold nanoparticles for rapid detection of mercury(Ⅱ) ions
摘要:
A rapid, sensitive, selective and reliable strip assay based on DNA-functionalized gold nanoparticles for Hg2+ detection has been developed, with a detection limit 5 nmol/L. The measurement principle was based on thymine-Hg2+-thymine (T-Hg2+-T) coordination chemistry and streptavidin-biotin interaction. The major advantages of this assay are that results can be read visually without any instrument in less than 10 min and that it does not require any sample pretreatment.
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关键词:
- Mercury (Ⅱ) ion
- / Test strip
- / Gold nanoparticles
- / DNA
English
Development of a test strip based on DNA-functionalized gold nanoparticles for rapid detection of mercury(Ⅱ) ions
Abstract:
A rapid, sensitive, selective and reliable strip assay based on DNA-functionalized gold nanoparticles for Hg2+ detection has been developed, with a detection limit 5 nmol/L. The measurement principle was based on thymine-Hg2+-thymine (T-Hg2+-T) coordination chemistry and streptavidin-biotin interaction. The major advantages of this assay are that results can be read visually without any instrument in less than 10 min and that it does not require any sample pretreatment.
-
Key words:
- Mercury (Ⅱ) ion
- / Test strip
- / Gold nanoparticles
- / DNA
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