Sulfamic acid as a cost-effective and recyclable solid acid catalyst for Friedel-Crafts alkylation of indole with α,β-unsaturated carbonyl compound and benzyl alcohol

Jing Yang ,  Juan Zhang ,  Tian Tian Chen ,  De Mei Sun ,  Ji Li ,  Xue Fen Wu

引用本文: Jing Yang,  Juan Zhang,  Tian Tian Chen,  De Mei Sun,  Ji Li,  Xue Fen Wu. Sulfamic acid as a cost-effective and recyclable solid acid catalyst for Friedel-Crafts alkylation of indole with α,β-unsaturated carbonyl compound and benzyl alcohol[J]. Chinese Chemical Letters, 2011, 22(12): 1391-1394. doi: 10.1016/j.cclet.2011.06.006 shu
Citation:  Jing Yang,  Juan Zhang,  Tian Tian Chen,  De Mei Sun,  Ji Li,  Xue Fen Wu. Sulfamic acid as a cost-effective and recyclable solid acid catalyst for Friedel-Crafts alkylation of indole with α,β-unsaturated carbonyl compound and benzyl alcohol[J]. Chinese Chemical Letters, 2011, 22(12): 1391-1394. doi: 10.1016/j.cclet.2011.06.006 shu

Sulfamic acid as a cost-effective and recyclable solid acid catalyst for Friedel-Crafts alkylation of indole with α,β-unsaturated carbonyl compound and benzyl alcohol

  • 基金项目:

    We gratefully acknowledge the financial support from the Doctoral Research Fund of Henan University of Traditional Chinese Medicine.

摘要: Sulfamic acid was proved to be a cost-effective and recyclable catalyst for Friedel-Crafts type reaction of indole with α, β-unsaturated carbonyl compound and benzyl alcohol. Various indoles, α, β-unsaturated carbonyl compounds and a benzyl alcohol were successfully used in this type of reaction, and the corresponding products were obtained in good to excellent yields.

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  • 收稿日期:  2011-04-25
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