Secondary metabolites from fungus Alternaria sp.CIB 108

Qian Feng Chen Min Zhou Tao Yang Xiao Zhen Chen Chun Wang Guo Lin Zhang Guo You Li

引用本文: Qian Feng Chen,  Min Zhou,  Tao Yang,  Xiao Zhen Chen,  Chun Wang,  Guo Lin Zhang,  Guo You Li. Secondary metabolites from fungus Alternaria sp.CIB 108[J]. Chinese Chemical Letters, 2011, 22(10): 1226-1228. doi: 10.1016/j.cclet.2011.05.036 shu
Citation:  Qian Feng Chen,  Min Zhou,  Tao Yang,  Xiao Zhen Chen,  Chun Wang,  Guo Lin Zhang,  Guo You Li. Secondary metabolites from fungus Alternaria sp.CIB 108[J]. Chinese Chemical Letters, 2011, 22(10): 1226-1228. doi: 10.1016/j.cclet.2011.05.036 shu

Secondary metabolites from fungus Alternaria sp.CIB 108

  • 基金项目:

    This work was supported financially by the NSFC (No.20902089 to G.Y.Li) and the Knowledge Innovation Program of the Chinese Academy of Sciences (No.KSCX2-EW-G-13-04).

摘要: A new compound, 3-butyryl-6-[rel-(1S, 2S)-1, 2-dihydroxypropyl]-4-hydroxy-2H-pyran-2-one (1), was isolated from the solid fermented rice culture of Alternaria sp. CIB 108, along with three known ones, deoxyradicinin (2), 3-epiradicinol (3), and 3-epideoxyradicinol (4). Their structures were elucidated on the basis of spectroscopic data. The single crystal X-ray diffraction was applied to further clarify the structure of 1. Furthermore, compounds 1-4 possessed no cytotoxicity against several cell lines (HeLa, HepG2, and Ros) and showed no antibacterial activity at 40 μmol/L.

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  • 收稿日期:  2011-02-22
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