引用本文:
A. Kuraitheerthakumaran, S. Pazhamalai, M. Gopalakrishnan. An efficient and solvent-free one-pot synthesis of 1,4-dihydropyridines under microwave irradiation[J]. Chinese Chemical Letters,
2011, 22(10): 1199-1202.
doi:
10.1016/j.cclet.2011.05.003
Citation: A. Kuraitheerthakumaran, S. Pazhamalai, M. Gopalakrishnan. An efficient and solvent-free one-pot synthesis of 1,4-dihydropyridines under microwave irradiation[J]. Chinese Chemical Letters, 2011, 22(10): 1199-1202. doi: 10.1016/j.cclet.2011.05.003
Citation: A. Kuraitheerthakumaran, S. Pazhamalai, M. Gopalakrishnan. An efficient and solvent-free one-pot synthesis of 1,4-dihydropyridines under microwave irradiation[J]. Chinese Chemical Letters, 2011, 22(10): 1199-1202. doi: 10.1016/j.cclet.2011.05.003
An efficient and solvent-free one-pot synthesis of 1,4-dihydropyridines under microwave irradiation
摘要:
An efficient synthesis of 1, 4-dihydropyridines using lanthanum oxide as a catalyst from aldehydes, β-ketoester and ammonium acetate without solvent under the irradiation of microwave is described. Compared with the classical Hantzsch reaction, this new method has the advantage of good yield (90-98%) and short reaction time (40-80 s).
English
An efficient and solvent-free one-pot synthesis of 1,4-dihydropyridines under microwave irradiation
Abstract:
An efficient synthesis of 1, 4-dihydropyridines using lanthanum oxide as a catalyst from aldehydes, β-ketoester and ammonium acetate without solvent under the irradiation of microwave is described. Compared with the classical Hantzsch reaction, this new method has the advantage of good yield (90-98%) and short reaction time (40-80 s).
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Key words:
- Hantzsch reaction
- / 1,4-Dihydropyridine
- / Microwave
- / Solvent free
- / Lanthanum oxide
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