Citation: Robabeh Baharfar, Razieh Azimi. A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media[J]. Chinese Chemical Letters, ;2011, 22(10): 1183-1186. doi: 10.1016/j.cclet.2011.04.020 shu

A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media

Faculty of Chemistry, Mazandaran University, Babolsar, Iran

Received Date: 17 February 2011

Fund Project: Financial support of this work from the Research Council of Mazandran University is gratefully acknowledged.

A series of pyrido[2, 3-d]pyrimidine derivatives were easily constructed by cyclocondensation reactions of 6-aminouracils or 6-aminothiouracil with α, β-unsaturated carbonyl compounds (aldehyde, ketone and ester) possessing a leaving group on the β position, in H₂O under reflux conditions.
- Pyrido[2,3-d]pyrimidine,
- 6-Aminothiouracil,
- Diethyl ethoxymethylenemalonate,
- α,β-Unsaturated carbonyl compounds
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