Citation:
Meng Gao, Cui Fen Lu Gui Chun Yang, Zu Xing Chen. A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support[J]. Chinese Chemical Letters,
;2011, 22(7): 823-826.
doi:
10.1016/j.cclet.2010.12.055
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In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-ary 1-2,5-dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.
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Keywords:
- Onium salt,
- Support,
- Synthesis,
- Pyridazines
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