引用本文:
Sandip N. Gavade, Ravi S. Balaskar, Madhav S. Mane, Pramod N. Pabrekar, Murlidhar S. Shingare, Dhananjay V. Mane. Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea[J]. Chinese Chemical Letters,
2011, 22(3): 292-295.
doi:
10.1016/j.cclet.2010.09.037
Citation: Sandip N. Gavade, Ravi S. Balaskar, Madhav S. Mane, Pramod N. Pabrekar, Murlidhar S. Shingare, Dhananjay V. Mane. Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea[J]. Chinese Chemical Letters, 2011, 22(3): 292-295. doi: 10.1016/j.cclet.2010.09.037
Citation: Sandip N. Gavade, Ravi S. Balaskar, Madhav S. Mane, Pramod N. Pabrekar, Murlidhar S. Shingare, Dhananjay V. Mane. Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea[J]. Chinese Chemical Letters, 2011, 22(3): 292-295. doi: 10.1016/j.cclet.2010.09.037
Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea
摘要:
The ligand free coupling reaction of phenyl urea with different functionalized aryl halides in the presence of air stable Cu2O and t-BuOK as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields. This method is milder than the palladium catalyzed arylation and avoids the use of toxic phosphine ligand.
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关键词:
- Microwave assisted
- / Ligand free
- / Copper catalyze
- / Phenyl urea
- / Aryl halides
English
Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea
Abstract:
The ligand free coupling reaction of phenyl urea with different functionalized aryl halides in the presence of air stable Cu2O and t-BuOK as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields. This method is milder than the palladium catalyzed arylation and avoids the use of toxic phosphine ligand.
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Key words:
- Microwave assisted
- / Ligand free
- / Copper catalyze
- / Phenyl urea
- / Aryl halides
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