Citation: Cai Sheng Wu, Jin Lan Zhang, Yan Ling Qiao, Yi Lin Wang, Zhi Rong Chen. Simultaneous determination of 14 β-lactam antibiotics in cosmetic products by liquid chromatography tandem mass spectrometry method[J]. Chinese Chemical Letters, ;2011, 22(3): 334-337. doi: 10.1016/j.cclet.2010.09.035 shu

Simultaneous determination of 14 β-lactam antibiotics in cosmetic products by liquid chromatography tandem mass spectrometry method

Institute of Materia Medico, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China

Received Date: 13 June 2010

Fund Project: We thank the Ministry of Public Health of the People’s Republic of China (No. 200802005) for financial support of this work.

In this study, a simple and rapid high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was established and validated to determine the 14 β-lactam antibiotics in cosmetic products, including 1 (ceftazidime), 2 (cefaclor), 3 (cefdinir), 4 (ampicillin), 5 (cefalexin), 6 (ceftezole), 7 (cefotaxim), 8 (cefradine), 9 (cefuroxime), 10 (cephazoline), 11 (cefathiamidine), 12 (cefoperazone), 13 (cafalotin), 14 (piperacillin).
- High-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS),
- Cosmetic,
- β-Lactam antibiotics
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