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Citation: Simone Véronique Fannang, Victor Kuete, Céline Mbazoa Djama, Marlise Diane J. Dongfack, Jean Duplex Wansi, François Tillequin, Elisabeth Seguin, Elizabeth Chosson, Jean Wandji. A new friedelane triterpenoid and saponin with moderate antimicrobial activity from the stems of Drypetes laciniata[J]. Chinese Chemical Letters, ;2011, 22(2): 171-174. doi: 10.1016/j.cclet.2010.09.022 shu

A new friedelane triterpenoid and saponin with moderate antimicrobial activity from the stems of Drypetes laciniata

a Laboratoire de Syntheèse et de Produits Naturels, Département de Chimie Organique de l'Université de Yaoundé-1, Faculté des Sciences, P.O. Box 812 Yaoundé, Cameroon;
b Department of Biochemistry, University of Dschang, Faculty of Science, P.O. Box 67 Dschang, Cameroon;
c Laboratoire de Pharmacognosie de l'Université Paris Descartes, UMR/CNRS No. 8638, Faculté des Sciences Biologiques et Pharmaceutiques, 4-Avenue de l'Observatoire, 75006 Paris, France;
d Department of Chemistry, University of Douala, Faculty of Science, P.O. Box 24157 Douala, Cameroon;
e Laboratoire de Pharmacognosie, UFR de Médecine Pharmacie Rouen, 22-Bld Gambetta, 76183 Rouen Cedex 1, France

Received Date: 6 May 2010

Fund Project: Paris Descartes, France" during his multiple research visits in the "Laboratoire de Pharmacognosie, Faculté des Sciences Biologiques et Pharmaceutiques de Paris".One of the authors (J. Wandji) is grateful for grant (No. F/2624-3F) from the International Foundation for Science (Sweden), and to the sponsorship of the "Université

A new friedelane-type triterpene named 3β-hydroxyfriedelane-7,12,22-trione, as well as nine known compounds were isolated from the whole stems of Drypetes laciniata Hutch. (Euphorbiaceae). Their structures were established on the basis of spectroscopic methods. The new triterpene derivative and a known saponin were tested for antimicrobial and antifungal activities and they appeared to be moderate active.
- Drypetes laciniata,
- Euphorbiaceae,
- Stem,
- Friedelane-type triterpenoid,
- Antimicrobial activity
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