Citation: Hong Zhao, Lin Shi, Jia Qing Cao, Wei Li, Xia Wen, Yu Qing Zhao. A new triterpene saponin from Panax japonicus C.A.Meyer var major (Burk.) C.Y.Wu et K.M.Feng[J]. Chinese Chemical Letters, ;2010, 21(10): 1216-1218. doi: 10.1016/j.cclet.2010.06.010 shu

A new triterpene saponin from Panax japonicus C.A.Meyer var major (Burk.) C.Y.Wu et K.M.Feng

Hong Zhao ^a,b, ,
Lin Shi ^c ,
Jia Qing Cao ^c ,
Wei Li ^c ,
Xia Wen ^d ,
Yu Qing Zhao ^c

a Heilongjiang University of Traditional Chinese Medicine, Haerbin 150040, China;
b Dalian University, Dalian 116622, China;
c School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;
d No. 1 Hospital of Dalian Jinzhou, Dalian 116016, China

Received Date: 8 March 2010

Fund Project: We are grateful to Dr.Hao Miao for the evaluation of the anticancer activities of the new compound.This work was financially supported by Chinese Academy of Nutritional Sciences,Shanghai Institutes for Biological Sciences.

One new triterpene saponin was isolated from Panax japonicus C. A. Meyer var major(Burk.)C. Y. Wu et K. M. Feng, and established as oleanolic acid 3-O-[β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl-6'-O-n-butyl ester]which showed moderate antitumor activities against the A2780 cells and OVCAR-3 cells. Its structure was established by means of spectral data, particularly NMR, including HSQC and HMBC techniques.
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